Cryptogenic organizing pneumonia laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]
Overview
Laboratory Findings
- There are no specific laboratory findings associated with cryptogenic organizing pneumonia.
- If there is the history of cryptogenic organizing pneumonia and patients present with a cough, fever, and dyspnea then following laboratory test has to be done:[1]
- Complete blood count with differentials- leukocytosis is found in most of the patients.[2]
- Blood urea nitrogen
- Creatinine
- Urinalysis
- ESR
- C-reactive protein
- To find the etiology of cryptogenic organizing pneumonia following tests are done:
- Test for antibodies to rule out connective tissue disorder.
- Antinuclear antibody
- Rheumatoid factor
- Anti-topoisomerase [anti-Scl70] antibodies
- Anti-centromere antibodies
- Anti-double-stranded DNA antibodies
- Anti-J01 antibodies
- To rule out pneumonia, following tests are done:[3]
- Blood cultures
- Sputum gram stain
- Sputum enzyme immunoassay (EIA)
- Immunofluorescence
- Polymerase chain reaction (PCR) for respiratory viruses
- Urinary studies for pneumococcal and Legionella antigen
- HIV testing
- Test for antibodies to rule out connective tissue disorder.
References
- ↑ Davison AG, Heard BE, McAllister WA, Turner-Warwick ME (1983). "Cryptogenic organizing pneumonitis". Q. J. Med. 52 (207): 382–94. PMID 6647749.
- ↑ Cordier JF (December 1993). "Cryptogenic organizing pneumonitis. Bronchiolitis obliterans organizing pneumonia". Clin. Chest Med. 14 (4): 677–92. PMID 8313672.
- ↑ Disayabutr S, Calfee CS, Collard HR, Wolters PJ (September 2015). "Interstitial lung diseases in the hospitalized patient". BMC Med. 13: 245. doi:10.1186/s12916-015-0487-0. PMC 4584017. PMID 26407727.