Goodpasture syndrome epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]
Overview
The prevalence of Goodpasture syndrome worldwide affects an estimated 1 per million persons, with high prevalence in Caucasians. The peak incidence of the disease occurs between the ages of 20 and 30 and again at 60 and 70. [1]
Epidemiology and Demographics
Incidence
- The incidence of Goodpasture syndrome is approximately 0.18 cases per 100,000 individuals worldwide.[2]
- The annual incidence of Goodpasture syndrome in Europe is estimated to range from 0.5 to 1 per 1 million persons.[3]
- The incidence of Goodpasture syndrome is around 1 per 2 million persons per year.
Prevalence
- The prevalence of Goodpasture syndrome is estimated to be 1 per million individuals annually.[4]
Age
- Goodpasture syndrome occurs in two age peaks.[1]
- The early onset Goodpasture syndrome is seen with individuals in the age group of 20 and 30.
- The late onset Goodpasture syndrome is seen with individuals in the age group of 60 to 70.
Gender
- Goodpasture syndrome affects men and women equally.[1]
- Males are at increased risk of developing Goodpasture syndrome in the second and third decade.
- Females are at an increased risk of developing the syndrome in the sixth to seventh decade.
Race
- Goodpasture syndrome usually affects individuals of the white race. Black individuals are less likely to develop Goodpasture syndrome.
- In European populations between 0.5-1 case per million individuals are seen every year. It is rarer in non-European populations.
Region
- The majority of Goodpasture syndrome cases are reported in ethnic groups of New Zealand.
References
- ↑ 1.0 1.1 1.2 Cui Z, Zhao MH (2011). "Advances in human antiglomerular basement membrane disease". Nat Rev Nephrol. 7 (12): 697–705. doi:10.1038/nrneph.2011.89. PMID 21769105.
- ↑ Kluth DC, Rees AJ (1999). "Anti-glomerular basement membrane disease". J Am Soc Nephrol. 10 (11): 2446–53. PMID 10541306.
- ↑ Fomegné G, Dratwa M, Wens R, Mesquita M, Van der Straaten M, Vanden Haute K; et al. (2006). "[Goodpasture disease]". Rev Med Brux. 27 (3): 162–6. PMID 16894954.
- ↑ Tang W, McDonald SP, Hawley CM, Badve SV, Boudville NC, Brown FG, Clayton PA, Campbell SB, de Zoysa JR, Johnson DW (March 2013). "Anti-glomerular basement membrane antibody disease is an uncommon cause of end-stage renal disease". Kidney Int. 83 (3): 503–10. doi:10.1038/ki.2012.375. PMID 23254902.