Monoclonal gammopathy of undetermined significance epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: - Omer Kamal, M.D.[2]
Overview
The incidence of Monoclonal gammopathy of undetermined significance is approximately 120 per 100,000 in men at age 50, and goes to 530 per 1000 by the age 90. Women however have 60 cases per 1000 at age 50 which goes upto 370 pwe 1000 at age 90.
Epidemiology and Demographics
Incidence
- The incidence of Monoclonal gammopathy of undetermined significance is approximately 120 per 100,000 in men at age 50, and goes to 530 per 1000 by the age 90. Women however have 60 cases per 1000 at age 50 which goes upto 370 pwe 1000 at age 90.[1]
- The incidence of Monoclonal gammopathy of undetermined significance was estimated to be higher per 100,000 in men than women worldwide.[2]
Prevalence
- The prevalence of [disease name] is different in different populations[2]
Age Prevalence[2] ≥50 3.2 ≥70 5.3 ≥85 7.5
Case-fatality rate/Mortality rate
- In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
- The case-fatality rate/mortality rate of [disease name] is approximately [number range].
Age
- Patients of all age groups may develop [disease name].
- The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
- [Disease name] commonly affects individuals younger than/older than [number of years] years of age.
- [Chronic disease name] is usually first diagnosed among [age group].
- [Acute disease name] commonly affects [age group].
Race
- There is no racial predilection to [disease name].
- [Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
Gender
- [Men] are more commonly affected by Monoclonal gammopathy of undetermined significance than [women]. The [men] to [women] ratio is approximately [2] to 1.[1]
Region
- The majority of [disease name] cases are reported in [geographical region].
- [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
Developed Countries
Developing Countries
References
- ↑ 1.0 1.1 Therneau TM, Kyle RA, Melton LJ, Larson DR, Benson JT, Colby CL, Dispenzieri A, Kumar S, Katzmann JA, Cerhan JR, Rajkumar SV (November 2012). "Incidence of monoclonal gammopathy of undetermined significance and estimation of duration before first clinical recognition". Mayo Clin. Proc. 87 (11): 1071–9. doi:10.1016/j.mayocp.2012.06.014. PMC 3541934. PMID 22883742.
- ↑ 2.0 2.1 2.2 Kyle RA, Therneau TM, Rajkumar SV, Larson DR, Plevak MF, Offord JR, Dispenzieri A, Katzmann JA, Melton LJ (March 2006). "Prevalence of monoclonal gammopathy of undetermined significance". N. Engl. J. Med. 354 (13): 1362–9. doi:10.1056/NEJMoa054494. PMID 16571879.
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