Small intestine cancer primary prevention
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2]
Overview
There are no established preventive measures to prohibit developing small intestinal cancers. However, limiting tobacco and alcohol use, moderate healthy diet consumption and treatment of gastroenteritis and other intestinal pathology with increased risk of carcinomatos changes in polyps, can decrease the incidence of small intestinal cancers.
Primary Prevention
There are no established primary preventive measures to prohibit developing small intestinal cancers. However, some measures for primary prevention of small intestine cancer include life style changes for modifiable risk factors. These are as follows:
- Treatment of celiac disease, Crohns disease can prevent progression to adenocarcinoma of small intestine.
- Smoking is a major risk factor for various cancers. Quitting smoking plays a major role in decreasing the risk of small intestine cancer. [1]
- People with genetic predisposition such as Peutz-Jeghers syndrome and adenomatous polyposis coli (APC) may undergo screening for early diagnosis.
- Limiting alcohol consumption may also decrease the risk of getting small intestine cancer.[2]
- Moderate diet and maintaining weight are life style modifications to decrease the risk of small intestine cancer, as obesity and unhealthy eating habits are associated with increased risk of small intestine cancer.[3]
- Biliary tract diseases such as cholecystitis and gallstones prevention and their early treatment may play a role in preventing small intestine cancer.[4]
- Eradication of Helicobacter pylori and prevention of peptic ulcer disease (PUD) are other important life style modifications for prevention of small intestine cancer.[5]
References
- ↑ Wu AH, Yu MC, Mack TM (March 1997). "Smoking, alcohol use, dietary factors and risk of small intestinal adenocarcinoma". Int. J. Cancer. 70 (5): 512–7. PMID 9052748.
- ↑ Lowenfels AB, Sonni A (July 1977). "Distribution of small bowel tumors". Cancer Lett. 3 (1–2): 83–6. PMID 890689.
- ↑ Schottenfeld D, Beebe-Dimmer JL, Vigneau FD (January 2009). "The epidemiology and pathogenesis of neoplasia in the small intestine". Ann Epidemiol. 19 (1): 58–69. doi:10.1016/j.annepidem.2008.10.004. PMC 3792582. PMID 19064190.
- ↑ Johansen C, Chow WH, Jørgensen T, Mellemkjaer L, Engholm G, Olsen JH (September 1996). "Risk of colorectal cancer and other cancers in patients with gall stones". Gut. 39 (3): 439–43. PMC 1383353. PMID 8949651.
- ↑ Amieva MR, El-Omar EM (January 2008). "Host-bacterial interactions in Helicobacter pylori infection". Gastroenterology. 134 (1): 306–23. doi:10.1053/j.gastro.2007.11.009. PMID 18166359.