POEMS syndrome history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Patients suffering from POEMS syndrome may have variable presentation and can present a diagnostic challenge for the clinician due to non-specific symtoms. Common symtoms of POEMS syndrome include numbness, tingling and weakness affecting extremities, fatigue, generalized pain in the body, foot drop, blurred vision, peripheral edema, dyspnea and hyperpigmentation. Less common symptoms include muscle weakness, diplopia, ocular pain and ascites.
History
Symptoms
Patients suffering from POEMS syndrome may have variable presentation and can present a diagnostic challenge for the clinician.
Common Symptoms
Common symptoms of POEMS syndrome include the following:
- Numbness, tingling and weakness in the feet, later affecting the legs and hands
- Fatigue
- Generalized pain
- Foot drop
- Blurred vision
- Peripheral edema
- Dyspnea
- Hyperpigmentation
Less Common Symptoms
Less common symtoms of POEMS syndrome include the following:
- Muscle weakness
- Diplopia
- Ocular pain
- Ascites