Interleukin 9
| interleukin 9 | |
|---|---|
| Identifiers | |
| Symbol | IL9 |
| Entrez | 3578 |
| HUGO | 6029 |
| OMIM | 146931 |
| RefSeq | NM_000590 |
| UniProt | P15248 |
| Other data | |
| Locus | Chr. 5 q31-q35 |
Overview
Interleukin 9 (IL-9) is a cytokine produced by T-cells and specifically by CD4+ helper cells. IL-9 elicits many functions on lymphoid cells and mast cell lineages. The gene encoding this cytokine has been thought to have a role in asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.