CRTC1

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CREB regulated transcription coactivator 1
Identifiers
Symbols CRTC1 ; FLJ14027; KIAA0616; MECT1; TORC1; WAMTP1
External IDs Template:OMIM5 Template:MGI HomoloGene41607
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

CREB regulated transcription coactivator 1, also known as CRTC1, is a human gene.[1]


See also

References

  1. "Entrez Gene: CRTC1 CREB regulated transcription coactivator 1".

Further reading

  • Takemori H, Kajimura J, Okamoto M (2007). "TORC-SIK cascade regulates CREB activity through the basic leucine zipper domain". FEBS J. 274 (13): 3202–9. doi:10.1111/j.1742-4658.2007.05889.x. PMID 17565599.
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548.
  • Ishikawa K, Nagase T, Suyama M; et al. (1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. PMID 9734811.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Tonon G, Modi S, Wu L; et al. (2003). "t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway". Nat. Genet. 33 (2): 208–13. doi:10.1038/ng1083. PMID 12539049.
  • Iourgenko V, Zhang W, Mickanin C; et al. (2003). "Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells". Proc. Natl. Acad. Sci. U.S.A. 100 (21): 12147–52. doi:10.1073/pnas.1932773100. PMID 14506290.
  • Conkright MD, Canettieri G, Screaton R; et al. (2003). "TORCs: transducers of regulated CREB activity". Mol. Cell. 12 (2): 413–23. PMID 14536081.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Enlund F, Behboudi A, Andrén Y; et al. (2004). "Altered Notch signaling resulting from expression of a WAMTP1-MAML2 gene fusion in mucoepidermoid carcinomas and benign Warthin's tumors". Exp. Cell Res. 292 (1): 21–8. PMID 14720503.
  • Grimwood J, Gordon LA, Olsen A; et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
  • Jin J, Smith FD, Stark C; et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
  • Screaton RA, Conkright MD, Katoh Y; et al. (2004). "The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector". Cell. 119 (1): 61–74. doi:10.1016/j.cell.2004.09.015. PMID 15454081.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Bittinger MA, McWhinnie E, Meltzer J; et al. (2005). "Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins". Curr. Biol. 14 (23): 2156–61. doi:10.1016/j.cub.2004.11.002. PMID 15589160.
  • Behboudi A, Winnes M, Gorunova L; et al. (2005). "Clear cell hidradenoma of the skin-a third tumor type with a t(11;19)--associated TORC1-MAML2 gene fusion". Genes Chromosomes Cancer. 43 (2): 202–5. doi:10.1002/gcc.20168. PMID 15729701.
  • Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
  • Komiya T, Park Y, Modi S; et al. (2006). "Sustained expression of Mect1-Maml2 is essential for tumor cell growth in salivary gland cancers carrying the t(11;19) translocation". Oncogene. 25 (45): 6128–32. doi:10.1038/sj.onc.1209627. PMID 16652146.
  • Siu YT, Chin KT, Siu KL; et al. (2006). "TORC1 and TORC2 coactivators are required for tax activation of the human T-cell leukemia virus type 1 long terminal repeats". J. Virol. 80 (14): 7052–9. doi:10.1128/JVI.00103-06. PMID 16809310.
  • Katoh Y, Takemori H, Lin XZ; et al. (2006). "Silencing the constitutive active transcription factor CREB by the LKB1-SIK signaling cascade". FEBS J. 273 (12): 2730–48. doi:10.1111/j.1742-4658.2006.05291.x. PMID 16817901.
  • Okabe M, Miyabe S, Nagatsuka H; et al. (2007). "MECT1-MAML2 fusion transcript defines a favorable subset of mucoepidermoid carcinoma". Clin. Cancer Res. 12 (13): 3902–7. doi:10.1158/1078-0432.CCR-05-2376. PMID 16818685.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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