GNAI1

Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
PDB rendering based on 1agr.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1agr​, 1as0​, 1as2​, 1as3​, 1bh2​, 1bof​, 1cip​, 1gdd​, 1gfi​, 1gg2​, 1gia​, 1gil​, 1git​, 1gp2​, 1kjy​, 1svk​, 1svs​, 1y3a​, 2g83​, 2gtp​, 2hlb​, 2ihb​, 2ik8​, 2ode​
Identifiers
Symbols	GNAI1 ; Gi
External IDs	Template:OMIM5 Template:MGI HomoloGene: 74417
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1, also known as GNAI1, is a human gene.

Further reading

• Sidhu A, Niznik HB (2000). "Coupling of dopamine receptor subtypes to multiple and diverse G proteins". Int. J. Dev. Neurosci. 18 (7): 669–77. PMID 10978845.
• Brown EJ, Frazier WA (2001). "Integrin-associated protein (CD47) and its ligands". Trends Cell Biol. 11 (3): 130–5. PMID 11306274.
• Raymond JR, Mukhin YV, Gelasco A; et al. (2002). "Multiplicity of mechanisms of serotonin receptor signal transduction". Pharmacol. Ther. 92 (2–3): 179–212. PMID 11916537.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jiang M, Pandey S, Tran VT, Fong HK (1991). "Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells". Proc. Natl. Acad. Sci. U.S.A. 88 (9): 3907–11. PMID 1902575.CS1 maint: Multiple names: authors list (link)
• Gennity JM, Siess W (1991). "Thrombin inhibits the pertussis-toxin-dependent ADP-ribosylation of a novel soluble Gi-protein in human platelets". Biochem. J. 279 ( Pt 3): 643–50. PMID 1953657.
• Itoh H, Toyama R, Kozasa T; et al. (1988). "Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs". J. Biol. Chem. 263 (14): 6656–64. PMID 2834384.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bray P, Carter A, Guo V; et al. (1987). "Human cDNA clones for an alpha subunit of Gi signal-transduction protein". Proc. Natl. Acad. Sci. U.S.A. 84 (15): 5115–9. PMID 3110783.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bloch DB, Bloch KD, Iannuzzi M; et al. (1988). "The gene for the alpha i1 subunit of human guanine nucleotide binding protein maps near the cystic fibrosis locus". Am. J. Hum. Genet. 42 (6): 884–8. PMID 3130752.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nagata K, Katada T, Tohkin M; et al. (1988). "GTP-binding proteins in human platelet membranes serving as the specific substrate of islet-activating protein, pertussis toxin". FEBS Lett. 237 (1–2): 113–7. PMID 3139448.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kagimoto S, Yamada Y, Kubota A; et al. (1994). "Human somatostatin receptor, SSTR2, is coupled to adenylyl cyclase in the presence of Gi alpha 1 protein". Biochem. Biophys. Res. Commun. 202 (2): 1188–95. doi:10.1006/bbrc.1994.2054. PMID 7914078.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nitta K, Uchida K, Kawashima A; et al. (1994). "Identification of GTP-binding proteins in human glomeruli". Nippon Jinzo Gakkai shi. 36 (1): 9–12. PMID 8107314.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Law SF, Zaina S, Sweet R; et al. (1994). "Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation". Mol. Pharmacol. 45 (4): 587–90. PMID 8183236.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Europe-Finner GN, Phaneuf S, Watson SP, López Bernal A (1993). "Identification and expression of G-proteins in human myometrium: up-regulation of G alpha s in pregnancy". Endocrinology. 132 (6): 2484–90. PMID 8504751.CS1 maint: Multiple names: authors list (link)
• Laugwitz KL, Allgeier A, Offermanns S; et al. (1996). "The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families". Proc. Natl. Acad. Sci. U.S.A. 93 (1): 116–20. PMID 8552586.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Andersson B, Wentland MA, Ricafrente JY; et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lee MJ, Evans M, Hla T (1996). "The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway". J. Biol. Chem. 271 (19): 11272–9. PMID 8626678.CS1 maint: Multiple names: authors list (link)
• De Vries L, Elenko E, Hubler L; et al. (1997). "GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits". Proc. Natl. Acad. Sci. U.S.A. 93 (26): 15203–8. PMID 8986788.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yu W, Andersson B, Worley KC; et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. PMID 9110174.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Popov S, Yu K, Kozasa T, Wilkie TM (1997). "The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitro". Proc. Natl. Acad. Sci. U.S.A. 94 (14): 7216–20. PMID 9207071.CS1 maint: Multiple names: authors list (link)
• Shuey DJ, Betty M, Jones PG; et al. (1998). "RGS7 attenuates signal transduction through the G(alpha q) family of heterotrimeric G proteins in mammalian cells". J. Neurochem. 70 (5): 1964–72. PMID 9572280.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)