POEMS syndrome physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Physical Examination

Appearance

• Anasarca or ascites may be present.

Skin

• Hyperpigmentation
• Nail clubbing
• Leuconychia
• Thickening of the skin
• Excess hair or hair in unusual places (hypertrichosis)
• Skin angiomas or haemangiomas
• There may be changes reminiscent of scleroderma

Eye

• Papilloedema
• Uveitis and preretinal haemorrhage may be present.

Abdomen

• Hepatomegaly
• Splenomegaly