Microangiopathic hemolytic anemia pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
In all causes, the mechanism of MAHA is the formation of a fibrin mesh due to increased activity of the system of coagulation.
Microscopic Pathology
The red blood cells are physically cut by these protein networks, and the fragments are identical to the schistocytes seen on light microscopy.