Aplastic anemia history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Aplastic anemia is seen secondary to a hypoplastic bone marrow causing pancytopenia (anemia, neutropenia, thrombocytopenia). The history and symptoms seen are secondary to these abnormalities.

Symptoms

• Anemia with malaise, fatigue pallor and associated symptoms
• Thrombocytopenia (low platelet counts), leading to increased risk of hemorrhage and bruising, menorrhagia in premenstural female.
• Leukopenia (low white blood cell count), leading to increased risk of infection