Interleukin 28

Interleukin 28A
Identifiers
Symbol	IL28A
Alt. symbols	, IFNL2
Entrez	282616
HUGO	18364
OMIM	607401
RefSeq	NM_172138
UniProt	Q8IZJ0
Other data
Locus	Chr. 19 q13.13

Interleukin 28B
Identifiers
Symbol	IL28B
Alt. symbols	, IFNL3
Entrez	282617
HUGO	18365
OMIM	607402
RefSeq	NM_172139
UniProt	Q8IZI9
Other data
Locus	Chr. 19 q13.13

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Interleukin-28 (IL-28) is a cytokine that comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses. IL-28A and IL-28B belong to the type III interferon family of cytokines and are highly similar (in amino acid sequence) to IL-29.

IL-28 genes are located near IL-29 on chromosome 19 in humans.