Small cell carcinoma of the lung history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-In-Chief: Guillermo Rodriguez Nava, M.D. [2]
Overview
Small cell lung cancer comprises 15% to 25% of bronchogenic carcinomas and it is the cancer most commnoly associated with a plethora of paraneoplastic syndromes.[1] It usually develops in the upper airways and involves the hilum and mediastinum. Most of the times, evidence of regional or distant metastases is found at the time patients present with small cell lung carcinoma. [2]
History
Symptoms
Early small cell carcinoma of the lung does not have any symptoms. Initial presenting symptoms may be airways related, but are often constitutional and attributable to metastases:[3][4]
- Cough 75%
- Weight loss 68%
- Dyspnea 60%
- Chest pain 49%
- Hemoptysis 35%
- Bone pain 25%
- Clubbing 20%
- Fever 20%
- Weakness 10%
- Superior vena cava syndrome 4%
- Dysphagia 2%
- New onset of wheezing and stridor 2%
Other health problems may also cause these symptoms. Only a doctor can tell for sure. A person with any of these symptoms should tell the doctor so that the problems can be diagnosed and treated as early as possible.
References
- ↑ Sher T, Dy GK, Adjei AA (2008). "Small cell lung cancer". Mayo Clin Proc. 83 (3): 355–67. doi:10.4065/83.3.355. PMID 18316005.
- ↑ Spiro SG, Gould MK, Colice GL, American College of Chest Physicians (2007). "Initial evaluation of the patient with lung cancer: symptoms, signs, laboratory tests, and paraneoplastic syndromes: ACCP evidenced-based clinical practice guidelines (2nd edition)". Chest. 132 (3 Suppl): 149S–160S. doi:10.1378/chest.07-1358. PMID 17873166.
- ↑ Grippi MA (1990). "Clinical aspects of lung cancer". Semin Roentgenol. 25 (1): 12–24. PMID 2181676.
- ↑ Hyde L, Hyde CI (1974). "Clinical manifestations of lung cancer". Chest. 65 (3): 299–306. PMID 4813837.