Atopic dermatitis epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ogechukwu Hannah Nnabude, MD
Overview
Atopic dermatitis affects 10-20% of children and 1-3% of adults in industrialized countries. Its prevalence has doubled in the past thirty years. Atopic dermatitis is significantly associated with African-American individuals and tends to affect metropolitan populations as compared to rural populations.
Epidemiology and Demographics
Prevalence
- The prevalence of atopic dermatitis is approximately 5,000-20,000 cases per 100,000 children, worldwide.[1][2]
- In 2003, the prevalence of atopic dermatitis was estimated to be 10,700 cases per 100,000 children in the United States.[3]
Age
- The prevalence of atopic dermatitis is up to 20% in children and up to 3% in adults.[4][5][6]
- The majority of atopic dermatitis patients have onset <5 years of age.
- Atopic dermatitis incidence is highest during infancy and early childhood.
Race
- Higher prevalence of atopic dermatitis was significantly associated with African-American individuals.[7][8][6]
- Of note, patients in different racial groups tend to manifest various clinical presentations. For example, trunk lesions of atopic dermatitis may affect all races, but tend to be more clear and have obvious margins in Asians.
Gender
- Atopic dermatitis affects men and women equally.
Region
- Atopic dermatitis is a common disease that tends to affect metropolitan populations as compared to rural populations.[7]
- Higher exposure to air pollution and household hygiene products in metropolitan and developed cities are potential explanations of this observation.
References
- ↑ Williams H, Robertson C, Stewart A, Aït-Khaled N, Anabwani G, Anderson R, Asher I, Beasley R, Björkstén B, Burr M, Clayton T, Crane J, Ellwood P, Keil U, Lai C, Mallol J, Martinez F, Mitchell E, Montefort S, Pearce N, Shah J, Sibbald B, Strachan D, von Mutius E, Weiland SK (January 1999). "Worldwide variations in the prevalence of symptoms of atopic eczema in the International Study of Asthma and Allergies in Childhood". J. Allergy Clin. Immunol. 103 (1 Pt 1): 125–38. PMID 9893196.
- ↑ Saito, Hirohisa. Much Atopy about the Skin: Genome-Wide Molecular Analysis of Atopic Eczema. International Archives of Allergy and Immunology 2005;137:319-325.
- ↑ Shaw TE, Currie GP, Koudelka CW, Simpson EL (January 2011). "Eczema prevalence in the United States: data from the 2003 National Survey of Children's Health". J. Invest. Dermatol. 131 (1): 67–73. doi:10.1038/jid.2010.251. PMC 3130508. PMID 20739951.
- ↑ Nutten S (2015). "Atopic dermatitis: global epidemiology and risk factors". Ann. Nutr. Metab. 66 Suppl 1: 8–16. doi:10.1159/000370220. PMID 25925336.
- ↑ Wang X, Shi XD, Li LF, Zhou P, Shen YW, Song QK (March 2017). "Prevalence and clinical features of adult atopic dermatitis in tertiary hospitals of China". Medicine (Baltimore). 96 (11): e6317. doi:10.1097/MD.0000000000006317. PMC 5369901. PMID 28296746.
- ↑ 6.0 6.1 Ständer, Sonja; Ropper, Allan H. (2021). "Atopic Dermatitis". New England Journal of Medicine. 384 (12): 1136–1143. doi:10.1056/NEJMra2023911. ISSN 0028-4793.
- ↑ 7.0 7.1 Shaw TE, Currie GP, Koudelka CW, Simpson EL (January 2011). "Eczema prevalence in the United States: data from the 2003 National Survey of Children's Health". J. Invest. Dermatol. 131 (1): 67–73. doi:10.1038/jid.2010.251. PMC 3130508. PMID 20739951.
- ↑ Williams HC, Pembroke AC, Forsdyke H, Boodoo G, Hay RJ, Burney PG (February 1995). "London-born black Caribbean children are at increased risk of atopic dermatitis". J. Am. Acad. Dermatol. 32 (2 Pt 1): 212–7. PMID 7829705.