Keratin 13 (or cytokeratin 13) is a protein that in humans is encoded by the KRT13gene.[1][2]
Keratin 13 is a type I cytokeratin, it is paired with keratin 4 and found in the suprabasal layers of non-cornified stratified epithelia. Mutations in the gene encoding this protein and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus.[3]
References
↑Romano V, Raimondi E, Bosco P, Feo S, Di Pietro C, Leube RE, Troyanovsky SM, Ceratto N (October 1992). "Chromosomal mapping of human cytokeratin 13 gene (KRT13)". Genomics. 14 (2): 495–7. doi:10.1016/S0888-7543(05)80250-2. PMID1385306.
↑Richard G, De Laurenzi V, Didona B, Bale SJ, Compton JG (December 1995). "Keratin 13 point mutation underlies the hereditary mucosal epithelial disorder white sponge nevus". Nat. Genet. 11 (4): 453–5. doi:10.1038/ng1295-453. PMID7493031.
Further reading
Jacques CM, Pereira AL, Maia V, et al. (2009). "Expression of cytokeratins 10, 13, 14 and 19 in oral lichen planus". J Oral Sci. 51 (3): 355–65. doi:10.2334/josnusd.51.355. PMID19776502.
Lu DP, Xing RD, Tatemoto Y, Osaki T (2006). "[Cytokeratin18, 13 and their gene expression in post-operative maxillary cyst linings with metaplastic epithelium]". Zhonghua Kou Qiang Yi Xue Za Zhi. 41 (6): 376–9. PMID16836912.
Ceratto N, Dobkin C, Carter M, et al. (1997). "Human type I cytokeratin genes are a compact cluster". Cytogenet. Cell Genet. 77 (3–4): 169–74. doi:10.1159/000134566. PMID9284906.
Olson GE, Winfrey VP, Blaeuer GL, et al. (2002). "Stage-specific expression of the intermediate filament protein cytokeratin 13 in luminal epithelial cells of secretory phase human endometrium and peri-implantation stage rabbit endometrium". Biol. Reprod. 66 (4): 1006–15. doi:10.1095/biolreprod66.4.1006. PMID11906920.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID9373149.
Rugg E, Magee G, Wilson N, et al. (1999). "Identification of two novel mutations in keratin 13 as the cause of white sponge naevus". Oral Dis. 5 (4): 321–4. doi:10.1111/j.1601-0825.1999.tb00097.x. PMID10561721.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID17081983.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID14702039.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID8125298.
Shibuya Y, Zhang J, Yokoo S, et al. (2003). "Constitutional mutation of keratin 13 gene in familial white sponge nevus". Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 96 (5): 561–5. doi:10.1016/s1079-2104(03)00372-x. PMID14600690.
Terrinoni A, Rugg EL, Lane EB, et al. (2001). "A novel mutation in the keratin 13 gene causing oral white sponge nevus". J. Dent. Res. 80 (3): 919–23. doi:10.1177/00220345010800031401. PMID11379896.
Waseem A, Alam Y, Dogan B, et al. (1998). "Isolation, sequence and expression of the gene encoding human keratin 13". Gene. 215 (2): 269–79. doi:10.1016/S0378-1119(98)00297-2. PMID9714826.
Raspollini MR, Fambrini M, Marchionni M, et al. (2007). "In situ adenocarcinoma and squamous carcinoma of uterine cervix. Pathological and immunohistochemical analysis with cytokeratin 13". Eur. J. Obstet. Gynecol. Reprod. Biol. 134 (2): 249–53. doi:10.1016/j.ejogrb.2006.07.047. PMID16949723.
