Peutz-Jeghers syndrome surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]
Overview
Surgery is the mainstay of treatment for Peutz-Jeghers syndrome. Surgical options include polypectomy, laparotomy in case of intussusception, and laser cosmetic therapy may be considered for mucocutaneous pigmentation.
Indications
Indications for surgery are as follows:[1][2]
- Copious rectal bleeding
- Intussusception
- Polyps greater than 1-1.5 cm in size
- Rapidly growing polyps The types of surgical procedures are as follows:
Surgery
The surgical procedures are as follows:[3]
- Polypectomy:
- Endoscopic mucosal resection
- Endoscopic submucosal resection
- Laparotomy and desvagination of intestinal loops may be needed in case of intussusception.
- Laser cosmetic therapy may be considered for mucocutaneous pigmentation.
References
- ↑ Giardiello, F; Trimbath, J (2006). "Peutz-Jeghers Syndrome and Management Recommendations". Clinical Gastroenterology and Hepatology. 4 (4): 408–415. doi:10.1016/j.cgh.2005.11.005. ISSN 1542-3565.
- ↑ Hofmann S, Barth TF, Kornmann M, Henne-Bruns D (2014). "Appendix carcinoid associated with the Peutz-Jeghers syndrome". Int J Surg Case Rep. 5 (12): 964–7. doi:10.1016/j.ijscr.2014.06.024. PMC 4276270. PMID 25460448.
- ↑ Repici, Alessandro; Anderloni, Andrea; Jovani, Manol; Hassan, Cesare (2014). "Advances, problems, and complications of polypectomy". Clinical and Experimental Gastroenterology: 285. doi:10.2147/CEG.S43084. ISSN 1178-7023.