Spina bifida history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
Early symptoms of patients with spina bifida include: Weakness or paralysis in the legs, Urinary incontinence, Bowel incontinence, Sensation problems in the lower extremity, Motor problems in the lower extrimity, Headache, orthopedic abnormalities, difficulties with executive functions, academic skills problems, learning disability and allergy to latex.
History and Symptoms
- Early symptoms of spina bifida include:[1][2][3][4][5][6][7][8][9]
- Weakness or paralysis in the legs.
- Urinary incontinence
- Bowel incontinence
- Sensation problems in the lower extremity
- Motor problems in the lower extrimity
- Headache
- Orthopedic abnormalities:
- Difficulties with executive functions including:
- Planning
- Organizing
- Initiating
- Memory
- Problem solving
- Abstraction
- Visual planning
- Attention problems
- Academic skills problems include problem in:
- Methematics
- Reading
- Writing
- Learning disability: 60% of children with spina bifida were diagnosed with a learning disability.
- Patients with spina bifida have an increased rate of allergy to latex, ranging from mild to life-threatening. Approximately 68% of newborns with spina bifida have allergy to latex. Avoidance of use of latex-containing products such as examination gloves and condoms is critical in all patients with spina bifida since born.[10][11][12][13]
References
- ↑ Edwards RJ, Witchell C, Pople IK (December 2003). "Chronic headaches in adults with spina bifida and associated hydrocephalus". Eur J Pediatr Surg. 13 Suppl 1: S13–7. doi:10.1055/s-2003-44751. PMID 14758561.
- ↑ Duncan BK (November 1985). "Isolation of insertion, deletion, and nonsense mutations of the uracil-DNA glycosylase (ung) gene of Escherichia coli K-12". J. Bacteriol. 164 (2): 689–95. PMID 2997126.
- ↑ Flenley DC (December 1985). "Disordered breathing during sleep: discussion paper". J R Soc Med. 78 (12): 1031–3. doi:10.1177/014107688507801211. PMID 4067977.
- ↑ Mitchell LE, Adzick NS, Melchionne J, Pasquariello PS, Sutton LN, Whitehead AS (2004). "Spina bifida". Lancet. 364 (9448): 1885–95. doi:10.1016/S0140-6736(04)17445-X. PMID 15555669.
- ↑ Lord RA, Smith GA, Nightingale MJ, Boulton FE (September 1992). "Platelet counting using plasma platelet concentrate samples". Transfus Med. 2 (3): 201–5. PMID 1308831.
- ↑ Burmeister R, Hannay HJ, Copeland K, Fletcher JM, Boudousquie A, Dennis M (June 2005). "Attention problems and executive functions in children with spina bifida and hydrocephalus". Child Neuropsychol. 11 (3): 265–83. doi:10.1080/092970490911324. PMID 16036451.
- ↑ Tarazi RA, Zabel TA, Mahone EM (July 2008). "Age-related differences in executive function among children with spina bifida/hydrocephalus based on parent behavior ratings". Clin Neuropsychol. 22 (4): 585–602. doi:10.1080/13854040701425940. PMID 17853154.
- ↑ Rose BM, Holmbeck GN (September 2007). "Attention and executive functions in adolescents with spina bifida". J Pediatr Psychol. 32 (8): 983–94. doi:10.1093/jpepsy/jsm042. PMID 17556398.
- ↑ Verhoef M, Lurvink M, Barf HA, Post MW, van Asbeck FW, Gooskens RH, Prevo AJ (June 2005). "High prevalence of incontinence among young adults with spina bifida: description, prediction and problem perception". Spinal Cord. 43 (6): 331–40. doi:10.1038/sj.sc.3101705. PMID 15685262.
- ↑ Engibous PJ, Kittle PE, Jones HL, Vance BJ (1993). "Latex allergy in patients with spina bifida". Pediatr Dent. 15 (5): 364–6. PMID 8302676.
- ↑ Bernardini R, Novembre E, Lombardi E, Mezzetti P, Cianferoni A, Danti DA, Mercurella A, Vierucci A (May 1999). "Risk factors for latex allergy in patients with spina bifida and latex sensitization". Clin. Exp. Allergy. 29 (5): 681–6. PMID 10231329.
- ↑ Wu LC, Morley BJ, Campbell RD (January 1987). "Cell-specific expression of the human complement protein factor B gene: evidence for the role of two distinct 5'-flanking elements". Cell. 48 (2): 331–42. PMID 3643061.
- ↑ Pittman T, Kiburz J, Gabriel K, Steinhardt G, Williams D, Slater J (1995). "Latex allergy in children with spina bifida". Pediatr Neurosurg. 22 (2): 96–100. doi:10.1159/000120883. PMID 7710979.