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{{Infobox_gene}}
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'''SNF-related serine/threonine-protein kinase''' is an [[enzyme]] that in humans is encoded by the ''SNRK'' [[gene]].<ref name="pmid8654423">{{cite journal | vauthors = Becker W, Heukelbach J, Kentrup H, Joost HG | title = Molecular cloning and characterization of a novel mammalian protein kinase harboring a homology domain that defines a subfamily of serine/threonine kinases | journal = Eur J Biochem | volume = 235 | issue = 3 | pages = 736–43 | date = Jul 1996 | pmid = 8654423 | pmc =  | doi = 10.1111/j.1432-1033.1996.00736.x }}</ref><ref name="pmid7788527">{{cite journal | vauthors = Nagase T, Miyajima N, Tanaka A, Sazuka T, Seki N, Sato S, Tabata S, Ishikawa K, Kawarabayasi Y, Kotani H | title = Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1 | journal = DNA Res | volume = 2 | issue = 1 | pages = 37–43 | date = Jul 1995 | pmid = 7788527 | pmc = | doi = 10.1093/dnares/2.1.37 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SNRK SNF related kinase| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54861| accessdate = }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== References ==
{{GNF_Protein_box
{{reflist}}
| image = 
| image_source = 
| PDB =
| Name = SNF related kinase
| HGNCid = 30598
| Symbol = SNRK
| AltSymbols =; DKFZp779A1866; FLJ20224; HSNFRK; KIAA0096
| OMIM = 
| ECnumber = 
| Homologene = 9797
| MGIid = 108104
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0000287 |text = magnesium ion binding}} {{GNF_GO|id=GO:0004674 |text = protein serine/threonine kinase activity}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0016740 |text = transferase activity}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006468 |text = protein amino acid phosphorylation}} {{GNF_GO|id=GO:0030099 |text = myeloid cell differentiation}} {{GNF_GO|id=GO:0043523 |text = regulation of neuron apoptosis}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 54861
    | Hs_Ensembl = ENSG00000163788
    | Hs_RefseqProtein = NP_060189
    | Hs_RefseqmRNA = NM_017719
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 3
    | Hs_GenLoc_start = 43303034
    | Hs_GenLoc_end = 43367631
    | Hs_Uniprot = Q9NRH2
    | Mm_EntrezGene = 20623
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = NM_133741
    | Mm_RefseqProtein = NP_598502
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
    | Mm_Uniprot = 
  }}
}}
'''SNF related kinase''', also known as '''SNRK''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SNRK SNF related kinase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54861| accessdate = }}</ref>


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== Further reading ==
{{PBB_Summary
| section_title =
| summary_text =
}}
 
==References==
{{reflist|2}}
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T | title = Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones | journal = DNA Res. | volume = 9 | issue = 3 | pages = 99–106 | year = 2003 | pmid = 12168954 | doi = 10.1093/dnares/9.3.99 }}
| citations =
* {{cite journal | vauthors = Iacobelli M, Wachsman W, McGuire KL | title = Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein | journal = J. Immunol. | volume = 165 | issue = 2 | pages = 860–8 | year = 2000 | pmid = 10878360 | doi = 10.4049/jimmunol.165.2.860 }}
*{{cite journal | author=Nakajima D, Okazaki N, Yamakawa H, ''et al.'' |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99-106 |year= 2003 |pmid= 12168954 |doi= }}
* {{cite journal | vauthors = Yoshida K, Yamada M, Nishio C, Konishi A, Hatanaka H | title = SNRK, a member of the SNF1 family, is related to low K(+)-induced apoptosis of cultured rat cerebellar granule neurons | journal = Brain Res. | volume = 873 | issue = 2 | pages = 274–82 | year = 2000 | pmid = 10930554 | doi = 10.1016/S0006-8993(00)02548-8 }}
*{{cite journal  | author=Nagase T, Miyajima N, Tanaka A, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. |journal=DNA Res. |volume=2 |issue= 1 |pages= 37-43 |year= 1995 |pmid= 7788527 |doi=  }}
* {{cite journal | vauthors = Bower KE, Zeller RW, Wachsman W, Martinez T, McGuire KL | title = Correlation of transcriptional repression by p21(SNFT) with changes in DNA.NF-AT complex interactions | journal = J. Biol. Chem. | volume = 277 | issue = 38 | pages = 34967–77 | year = 2002 | pmid = 12087103 | doi = 10.1074/jbc.M205048200 }}
*{{cite journal  | author=Becker W, Heukelbach J, Kentrup H, Joost HG |title=Molecular cloning and characterization of a novel mammalian protein kinase harboring a homology domain that defines a subfamily of serine/threonine kinases. |journal=Eur. J. Biochem. |volume=235 |issue= 3 |pages= 736-43 |year= 1996 |pmid= 8654423 |doi=  }}
* {{cite journal | vauthors = Kertesz N, Samson J, Debacker C, Wu H, Labastie MC | title = Cloning and characterization of human and mouse SNRK sucrose non-fermenting protein (SNF-1)-related kinases | journal = Gene | volume = 294 | issue = 1–2 | pages = 13–24 | year = 2003 | pmid = 12234663 | doi = 10.1016/S0378-1119(02)00829-6 }}
*{{cite journal | author=Iacobelli M, Wachsman W, McGuire KL |title=Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein. |journal=J. Immunol. |volume=165 |issue= 2 |pages= 860-8 |year= 2000 |pmid= 10878360 |doi= }}
* {{cite journal | vauthors = Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S | title = Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions | journal = Genome Res. | volume = 14 | issue = 9 | pages = 1711–8 | year = 2004 | pmid = 15342556 | pmc = 515316 | doi = 10.1101/gr.2435604 }}
*{{cite journal | author=Yoshida K, Yamada M, Nishio C, ''et al.'' |title=SNRK, a member of the SNF1 family, is related to low K(+)-induced apoptosis of cultured rat cerebellar granule neurons. |journal=Brain Res. |volume=873 |issue= 2 |pages= 274-82 |year= 2000 |pmid= 10930554 |doi= }}
* {{cite journal | vauthors = Jaleel M, McBride A, Lizcano JM, Deak M, Toth R, Morrice NA, Alessi DR | title = Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate | journal = FEBS Lett. | volume = 579 | issue = 6 | pages = 1417–23 | year = 2005 | pmid = 15733851 | doi = 10.1016/j.febslet.2005.01.042 }}
*{{cite journal | author=Bower KE, Zeller RW, Wachsman W, ''et al.'' |title=Correlation of transcriptional repression by p21(SNFT) with changes in DNA.NF-AT complex interactions. |journal=J. Biol. Chem. |volume=277 |issue= 38 |pages= 34967-77 |year= 2002 |pmid= 12087103 |doi= 10.1074/jbc.M205048200 }}
*{{cite journal | author=Kertesz N, Samson J, Debacker C, ''et al.'' |title=Cloning and characterization of human and mouse SNRK sucrose non-fermenting protein (SNF-1)-related kinases. |journal=Gene |volume=294 |issue= 1-2 |pages= 13-24 |year= 2003 |pmid= 12234663 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Suzuki Y, Yamashita R, Shirota M, ''et al.'' |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711-8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Jaleel M, McBride A, Lizcano JM, ''et al.'' |title=Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate. |journal=FEBS Lett. |volume=579 |issue= 6 |pages= 1417-23 |year= 2005 |pmid= 15733851 |doi= 10.1016/j.febslet.2005.01.042 }}
*{{cite journal  | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
*{{cite journal  | author=Ewing RM, Chu P, Elisma F, ''et al.'' |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 }}
}}
{{refend}}
{{refend}}


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{{Serine/threonine-specific protein kinases}}
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[[Category:EC 2.7.11]]

Latest revision as of 02:30, 27 October 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

SNF-related serine/threonine-protein kinase is an enzyme that in humans is encoded by the SNRK gene.[1][2][3]

References

  1. ↑ Becker W, Heukelbach J, Kentrup H, Joost HG (Jul 1996). "Molecular cloning and characterization of a novel mammalian protein kinase harboring a homology domain that defines a subfamily of serine/threonine kinases". Eur J Biochem. 235 (3): 736–43. doi:10.1111/j.1432-1033.1996.00736.x. PMID 8654423.
  2. ↑ Nagase T, Miyajima N, Tanaka A, Sazuka T, Seki N, Sato S, Tabata S, Ishikawa K, Kawarabayasi Y, Kotani H (Jul 1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (1): 37–43. doi:10.1093/dnares/2.1.37. PMID 7788527.
  3. ↑ "Entrez Gene: SNRK SNF related kinase".

Further reading


Retrieved from "https://www.wikidoc.org/index.php?title=SNRK&oldid=1413239"