Follicular lymphoma: Difference between revisions

	Follicular lymphoma Microchapters
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Latest revision as of 01:25, 28 December 2018

For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2] Jogeet Singh Sekhon, M.D. [3]

Synonyms and keywords: FL; Centroblastic and centrocytic lymphoma; Brill-Symmers Disease.

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Follicular lymphoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Treatment

Medical Therapy | Surgery | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

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 __NOTOC__
-{{Infobox_Disease |
-  Name           = {{PAGENAME}} |
-  Image          = |
-  Caption        = |
-  DiseasesDB     = |
-  ICD10          = {{ICD10|C|82||c|81}} |
-  ICD9           = {{ICD9|202.0}}  |
-  ICDO           = |
-  OMIM           = |
-  MedlinePlus    = |
-  MeshID         = D008224 |
-}}
 {{Follicular lymphoma}}
-{{CMG}}
-==Overview==
+'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
-==Pathophysiology==
+{{CMG}}; {{AE}} {{AS}} {{JSS}}
-The [[tumor]] is composed of follicle center cells, usually a mixture of centrocytes (cleaved follicle center cells, "small cells") and centroblasts (large noncleaved follicle center cells, "[[large cells]]"). Centrocytes typically predominate; centroblasts are usually in the minority, but by definition are always present. Rare lymphomas with a follicular growth pattern consist almost entirely of centroblasts. Occasional cases may show [[plasmacytoid]] differentiation of foci of [[marginal zone]] or [[monocytoid]] B-cells.
-==Causes==
+{{SK}} FL; Centroblastic and centrocytic lymphoma; Brill-Symmers Disease.
-A [[translocation]] between [[chromosome]] 14 and 18 results in the overexpression of the ''bcl''2 [[gene]]. This overexpression causes a blockage of [[apoptosis]], or programmed cell death. This translocation has been associated with the development of Follicular lymphoma.
+==[[Follicular lymphoma overview|Overview]]==
+==[[Follicular lymphoma historical perspective|Historical Perspective]]==
+==[[Follicular lymphoma classification|Classification]]==
+==[[Follicular lymphoma pathophysiology|Pathophysiology]]==
+==[[Follicular lymphoma causes|Causes]]==
+==[[Follicular lymphoma differential diagnosis|Differentiating Follicular lymphoma from other Diseases]]==
+==[[Follicular lymphoma epidemiology and demographics|Epidemiology and Demographics]]==
+==[[Follicular lymphoma risk factors|Risk Factors]]==
+==[[Follicular lymphoma screening|Screening]]==
+==[[Follicular lymphoma natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
+==Diagnosis==
+[[Follicular  lymphoma staging|Staging]] | [[Follicular lymphoma history and symptoms|History and Symptoms]] | [[Follicular lymphoma physical examination|Physical Examination]] | [[Follicular lymphoma laboratory findings|Laboratory Findings]] | [[Follicular lymphoma chest x ray|Chest X Ray]] | [[Follicular lymphoma CT|CT]] | [[Follicular lymphoma MRI|MRI]] | [[Follicular lymphoma ultrasound|Ultrasound]] | [[Follicular lymphoma biopsy|Biopsy]] | [[Follicular lymphoma other imaging findings|Other Imaging Findings]] | [[Follicular lymphoma other diagnostic studies|Other Diagnostic Studies]]
 ==Treatment==
-There is no consensus regarding the best treatment [[algorithm]], but watch-and-wait policies, [[alkylators]], [[anthracycline]]-containing regimens (eg. [[CHOP]]), [[rituximab]], [[autologous]] and [[allogenic]] [[hematopoietic stem cell transplantation]] have all been applied. The disease is regarded as incurable (although allogenic stem cell transplantation may be curative, the [[death|mortality]] from the procedure is too high to be a first line option). The exception is localized disease, which can be cured by local [[irradiation]]. The typical pattern is one of good responses from treatment, followed by relapses some years later. [[Median]] survival is around 10 years, but the range is wide, from less than one year, to more than 20 years. Some patients may never need treatment.
+[[Follicular lymphoma medical therapy|Medical Therapy]] | [[Follicular lymphoma surgery|Surgery]] | [[Follicular lymphoma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Follicular lymphoma future or investigational therapies|Future or Investigational Therapies]]
-==References==
+==Case Studies==
-<references/>
+[[Follicular lymphoma case study one|Case #1]]
 [[Category:Hematology]]
 [[Category:Types of cancer]]
 [[Category:Oncology]]
-[[Category:Needs content]]
 {{Hematological malignancy histology}}
-[[de: Follikuläres Lymphom]]
 {{WikiDoc Help Menu}}
 {{WikiDoc Sources}}
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]
+[[Category:Hematology]]
+[[Category:Immunology]]

v t e Myeloid Hematological malignancy/leukemia histology (ICD-O 9590-9989, C81-C96, 200-208)
CFU-GM/ and other granulocytes	Template:Navbox subgroup
MEP	Template:Navbox subgroup
CFU-Mast	Mastocytoma (Mast cell leukemia, Mast cell sarcoma, Systemic mastocytosis)
Multiple/unknown	AML (Acute panmyelosis with myelofibrosis, Myeloid sarcoma) · MP (Myelofibrosis) · Acute biphenotypic leukaemia
See also hematology, lymphoid malignancy

Follicular lymphoma: Difference between revisions

Latest revision as of 01:25, 28 December 2018

Diagnosis

Treatment

Case Studies

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