SLC7A4: Difference between revisions

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{{Infobox_gene}}
{{GNF_Protein_box
'''Cationic amino acid transporter 4''' is a [[protein]] that in humans is encoded by the ''SLC7A4'' [[gene]].<ref name="pmid9598310">{{cite journal | vauthors = Sperandeo MP, Borsani G, Incerti B, Zollo M, Rossi E, Zuffardi O, Castaldo P, Taglialatela M, Andria G, Sebastio G | title = The gene encoding a cationic amino acid transporter (SLC7A4) maps to the region deleted in the velocardiofacial syndrome | journal = Genomics | volume = 49 | issue = 2 | pages = 230–6 |date=Aug 1998 | pmid = 9598310 | pmc = | doi = 10.1006/geno.1998.5252 }}</ref><ref name="pmid11665818">{{cite journal | vauthors = Hammermann R, Brunn G, Racke K | title = Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4 | journal = Amino Acids | volume = 21 | issue = 2 | pages = 211–9 |date=Oct 2001 | pmid = 11665818 | pmc =  | doi =10.1007/s007260170029 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC7A4 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6545| accessdate = }}</ref>
| image = 
| image_source = 
| PDB =
| Name = Solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
| HGNCid = 11062
| Symbol = SLC7A4
| AltSymbols =; VH; CAT-4; CAT4; HCAT3; MGC129976; MGC129977
| OMIM = 603752
| ECnumber = 
| Homologene = 20883
| MGIid = 2146512
| GeneAtlas_image1 = PBB_GE_SLC7A4_214406_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_SLC7A4_205864_at_tn.png
| Function = {{GNF_GO|id=GO:0005279 |text = amine transmembrane transporter activity}}{{GNF_GO|id=GO:0015174 |text = basic amino acid transmembrane transporter activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0006520 |text = amino acid metabolic process}} {{GNF_GO|id=GO:0006810 |text = transport}} {{GNF_GO|id=GO:0006865 |text = amino acid transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6545
    | Hs_Ensembl = ENSG00000099960
    | Hs_RefseqProtein = NP_004164
    | Hs_RefseqmRNA = NM_004173
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 22
    | Hs_GenLoc_start = 19713008
    | Hs_GenLoc_end = 19716847
    | Hs_Uniprot = O43246
    | Mm_EntrezGene = 224022
    | Mm_Ensembl = ENSMUSG00000022756
    | Mm_RefseqmRNA = NM_144852
    | Mm_RefseqProtein = NP_659101
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 16
    | Mm_GenLoc_start = 17485581
    | Mm_GenLoc_end = 17490234
    | Mm_Uniprot =   
  }}
}}
'''Solute carrier family 7 (cationic amino acid transporter, y+ system), member 4''', also known as '''SLC7A4''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SLC7A4 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6545| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
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{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Muñoz L, Lasa A, Carricondo MT, ''et al.'' |title=Comparative analysis of ZAP-70 expression and Ig VH mutational status in B-cell chronic lymphocytic leukemia. |journal=Cytometry. Part B, Clinical cytometry |volume=72 |issue= 2 |pages= 96-102 |year= 2007 |pmid= 17051526 |doi= 10.1002/cyto.b.20149 }}
*{{cite journal   |vauthors=Muñoz L, Lasa A, Carricondo MT, etal |title=Comparative analysis of ZAP-70 expression and Ig VH mutational status in B-cell chronic lymphocytic leukemia. |journal=Cytometry Part B |volume=72 |issue= 2 |pages= 96–102 |year= 2007 |pmid= 17051526 |doi= 10.1002/cyto.b.20149 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Collins JE, Wright CL, Edwards CA, ''et al.'' |title=A genome annotation-driven approach to cloning the human ORFeome. |journal=Genome Biol. |volume=5 |issue= 10 |pages= R84 |year= 2005 |pmid= 15461802 |doi= 10.1186/gb-2004-5-10-r84 }}
*{{cite journal   |vauthors=Collins JE, Wright CL, Edwards CA, etal |title=A genome annotation-driven approach to cloning the human ORFeome. |journal=Genome Biol. |volume=5 |issue= 10 |pages= R84 |year= 2005 |pmid= 15461802 |doi= 10.1186/gb-2004-5-10-r84 | pmc=545604 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Wolf S, Janzen A, Vékony N, ''et al.'' |title=Expression of solute carrier 7A4 (SLC7A4) in the plasma membrane is not sufficient to mediate amino acid transport activity. |journal=Biochem. J. |volume=364 |issue= Pt 3 |pages= 767-75 |year= 2002 |pmid= 12049641 |doi= 10.1042/BJ20020084 }}
*{{cite journal   |vauthors=Wolf S, Janzen A, Vékony N, etal |title=Expression of solute carrier 7A4 (SLC7A4) in the plasma membrane is not sufficient to mediate amino acid transport activity. |journal=Biochem. J. |volume=364 |issue= Pt 3 |pages= 767–75 |year= 2002 |pmid= 12049641 |doi= 10.1042/BJ20020084  | pmc=1222626 }}
*{{cite journal | author=Hammermann R, Brunn G, Racké K |title=Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4. |journal=Amino Acids |volume=21 |issue= 2 |pages= 211-9 |year= 2002 |pmid= 11665818 |doi=  }}
*{{cite journal  | vauthors=Neshat MN, Goodglick L, Lim K, Braun J |title=Mapping the B cell superantigen binding site for HIV-1 gp120 on a V(H)3 Ig. |journal=Int. Immunol. |volume=12 |issue= 3 |pages= 305–12 |year= 2000 |pmid= 10700465 |doi=10.1093/intimm/12.3.305 }}
*{{cite journal  | author=Neshat MN, Goodglick L, Lim K, Braun J |title=Mapping the B cell superantigen binding site for HIV-1 gp120 on a V(H)3 Ig. |journal=Int. Immunol. |volume=12 |issue= 3 |pages= 305-12 |year= 2000 |pmid= 10700465 |doi=  }}
*{{cite journal  | vauthors=Fischer M, Küppers R |title=Human IgA- and IgM-secreting intestinal plasma cells carry heavily mutated VH region genes. |journal=Eur. J. Immunol. |volume=28 |issue= 9 |pages= 2971–7 |year= 1998 |pmid= 9754584 |doi=10.1002/(SICI)1521-4141(199809)28:09<2971::AID-IMMU2971>3.0.CO;2-3  }}
*{{cite journal  | author=Fischer M, Küppers R |title=Human IgA- and IgM-secreting intestinal plasma cells carry heavily mutated VH region genes. |journal=Eur. J. Immunol. |volume=28 |issue= 9 |pages= 2971-7 |year= 1998 |pmid= 9754584 |doi= }}
*{{cite journal  | author=Sperandeo MP, Borsani G, Incerti B, ''et al.'' |title=The gene encoding a cationic amino acid transporter (SLC7A4) maps to the region deleted in the velocardiofacial syndrome. |journal=Genomics |volume=49 |issue= 2 |pages= 230-6 |year= 1998 |pmid= 9598310 |doi= 10.1006/geno.1998.5252 }}
}}
}}
{{refend}}
{{refend}}


{{membrane-protein-stub}}
{{NLM content}}
{{NLM content}}
{{Membrane transport proteins}}
{{Membrane transport proteins}}
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[[Category:Solute carrier family]]
[[Category:Solute carrier family]]
{{WikiDoc Sources}}
 
 
{{membrane-protein-stub}}

Latest revision as of 12:23, 9 January 2019

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Cationic amino acid transporter 4 is a protein that in humans is encoded by the SLC7A4 gene.[1][2][3]


See also

References

  1. ↑ Sperandeo MP, Borsani G, Incerti B, Zollo M, Rossi E, Zuffardi O, Castaldo P, Taglialatela M, Andria G, Sebastio G (Aug 1998). "The gene encoding a cationic amino acid transporter (SLC7A4) maps to the region deleted in the velocardiofacial syndrome". Genomics. 49 (2): 230–6. doi:10.1006/geno.1998.5252. PMID 9598310.
  2. ↑ Hammermann R, Brunn G, Racke K (Oct 2001). "Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4". Amino Acids. 21 (2): 211–9. doi:10.1007/s007260170029. PMID 11665818.
  3. ↑ "Entrez Gene: SLC7A4 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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