SLC25A11: Difference between revisions

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Latest revision as of 11:16, 30 December 2018

Mitochondrial 2-oxoglutarate/malate carrier protein is a protein that in humans is encoded by the SLC25A11 gene.^[1]^[2]^[3] Inactivating mutations in this gene predispose to metastasic paraganglioma.^[4]

References

↑ Piccininni S, Iacobazzi V, Lauria G, Rocchi M, Palmieri F (Mar 1999). "Assignment of the oxoglutarate carrier gene (SLC20A4) to human chromosome 17p13.3". Cytogenet Cell Genet. 83 (3–4): 256–7. doi:10.1159/000015198. PMID 10072597.
↑ Iacobazzi V, Palmieri F, Runswick MJ, Walker JE (Jan 1993). "Sequences of the human and bovine genes for the mitochondrial 2-oxoglutarate carrier". DNA Seq. 3 (2): 79–88. doi:10.3109/10425179209034000. PMID 1457818.
↑ "Entrez Gene: SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11".
↑ Buffet, Alexandre; Morin, Aurelie; Castro-Vega, Luis-Jaime; Habarou, Florence; Lussey-Lepoutre, Charlotte; Letouzé, Eric; Lefebvre, Hervé; Guilhem, Isabelle; Magalie, Haissaguerre (2018-02-05). "Germline mutations in the mitochondrial 2-oxoglutarate/malate carrier SLC25A11 gene confer a predisposition to metastatic paragangliomas". Cancer Research. 78 (8): 1914–1922. doi:10.1158/0008-5472.CAN-17-2463. ISSN 1538-7445. PMID 29431636.

Bisaccia F, Zara V, Capobianco L, et al. (1996). "The formation of a disulfide cross-link between the two subunits demonstrates the dimeric structure of the mitochondrial oxoglutarate carrier". Biochim. Biophys. Acta. 1292 (2): 281–88. doi:10.1016/0167-4838(95)00215-4. PMID 8597574.
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Bisaccia F, Capobianco L, Mazzeo M, Palmieri F (1996). "The mitochondrial oxoglutarate carrier protein contains a disulfide bridge between intramembranous cysteines 221 and 224". FEBS Lett. 392 (1): 54–8. doi:10.1016/0014-5793(96)00784-3. PMID 8769314.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Palmisano A, Zara V, Hönlinger A, et al. (1998). "Targeting and assembly of the oxoglutarate carrier: general principles for biogenesis of carrier proteins of the mitochondrial inner membrane". Biochem. J. 333 ( Pt 1) (Pt 1): 151–8. PMC 1219567. PMID 9639574.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Coll O, Colell A, García-Ruiz C, et al. (2003). "Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion". Hepatology. 38 (3): 692–702. doi:10.1053/jhep.2003.50351. PMID 12939596.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514.
Kabe Y, Ohmori M, Shinouchi K, et al. (2006). "Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier". J. Biol. Chem. 281 (42): 31729–35. doi:10.1074/jbc.M604729200. PMID 16920706.

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This membrane protein–related article is a stub. You can help Wikipedia by expanding it.

[pmid10072597-1] Piccininni S, Iacobazzi V, Lauria G, Rocchi M, Palmieri F (Mar 1999). "Assignment of the oxoglutarate carrier gene (SLC20A4) to human chromosome 17p13.3". Cytogenet Cell Genet. 83 (3–4): 256–7. doi:10.1159/000015198. PMID 10072597.

[pmid1457818-2] Iacobazzi V, Palmieri F, Runswick MJ, Walker JE (Jan 1993). "Sequences of the human and bovine genes for the mitochondrial 2-oxoglutarate carrier". DNA Seq. 3 (2): 79–88. doi:10.3109/10425179209034000. PMID 1457818.

[entrez-3] "Entrez Gene: SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11".

[4] Buffet, Alexandre; Morin, Aurelie; Castro-Vega, Luis-Jaime; Habarou, Florence; Lussey-Lepoutre, Charlotte; Letouzé, Eric; Lefebvre, Hervé; Guilhem, Isabelle; Magalie, Haissaguerre (2018-02-05). "Germline mutations in the mitochondrial 2-oxoglutarate/malate carrier SLC25A11 gene confer a predisposition to metastatic paragangliomas". Cancer Research. 78 (8): 1914–1922. doi:10.1158/0008-5472.CAN-17-2463. ISSN 1538-7445. PMID 29431636.

[1]

[2]

[3]

[4]

@@ Line 1: / Line 1: @@
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+{{Infobox_gene}}
-{{PBB_Controls
+'''Mitochondrial 2-oxoglutarate/malate carrier protein''' is a [[protein]] that in humans is encoded by the ''SLC25A11'' [[gene]].<ref name="pmid10072597">{{cite journal | vauthors = Piccininni S, Iacobazzi V, Lauria G, Rocchi M, Palmieri F | title = Assignment of the oxoglutarate carrier gene (SLC20A4) to human chromosome 17p13.3 | journal = Cytogenet Cell Genet | volume = 83 | issue = 3–4 | pages = 256–7 |date=Mar 1999 | pmid = 10072597 | pmc =  | doi =10.1159/000015198  }}</ref><ref name="pmid1457818">{{cite journal | vauthors = Iacobazzi V, Palmieri F, Runswick MJ, Walker JE | title = Sequences of the human and bovine genes for the mitochondrial 2-oxoglutarate carrier | journal = DNA Seq | volume = 3 | issue = 2 | pages = 79–88 |date=Jan 1993 | pmid = 1457818 | pmc =  | doi =  10.3109/10425179209034000}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8402| accessdate = }}</ref> Inactivating mutations in this gene predispose to [[Metastasis|metastasic]] [[paraganglioma]].<ref>{{Cite journal|last=Buffet|first=Alexandre|last2=Morin|first2=Aurelie|last3=Castro-Vega|first3=Luis-Jaime|last4=Habarou|first4=Florence|last5=Lussey-Lepoutre|first5=Charlotte|last6=Letouzé|first6=Eric|last7=Lefebvre|first7=Hervé|last8=Guilhem|first8=Isabelle|last9=Magalie|first9=Haissaguerre|date=2018-02-05|title=Germline mutations in the mitochondrial 2-oxoglutarate/malate carrier SLC25A11 gene confer a predisposition to metastatic paragangliomas|journal=Cancer Research|volume=78|issue=8|pages=1914–1922|doi=10.1158/0008-5472.CAN-17-2463|issn=1538-7445|pmid=29431636}}</ref>
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-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
- | HGNCid = 10981
- | Symbol = SLC25A11
- | AltSymbols =; OGC; SLC20A4
- | OMIM = 604165
- | ECnumber =
- | Homologene = 2637
- | MGIid = 1915113
-  | GeneAtlas_image1 = PBB_GE_SLC25A11_209003_at_tn.png
-  | GeneAtlas_image2 = PBB_GE_SLC25A11_207088_s_at_tn.png
- | Function = {{GNF_GO|id=GO:0005215 |text = transporter activity}} {{GNF_GO|id=GO:0005488 |text = binding}} {{GNF_GO|id=GO:0015367 |text = oxoglutarate:malate antiporter activity}}
- | Component = {{GNF_GO|id=GO:0005739 |text = mitochondrion}} {{GNF_GO|id=GO:0005743 |text = mitochondrial inner membrane}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
- | Process = {{GNF_GO|id=GO:0006810 |text = transport}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 8402
-    | Hs_Ensembl = ENSG00000108528
-    | Hs_RefseqProtein = NP_003553
-    | Hs_RefseqmRNA = NM_003562
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 17
-    | Hs_GenLoc_start = 4781169
-    | Hs_GenLoc_end = 4784208
-    | Hs_Uniprot = Q02978
-    | Mm_EntrezGene = 67863
-    | Mm_Ensembl = ENSMUSG00000014606
-    | Mm_RefseqmRNA = NM_024211
-    | Mm_RefseqProtein = NP_077173
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 11
-    | Mm_GenLoc_start = 70460391
-    | Mm_GenLoc_end = 70463188
-    | Mm_Uniprot = Q5SX46
-  }}
-}}
-'''Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11''', also known as '''SLC25A11''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8402| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
@@ Line 59: / Line 12: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
@@ Line 65: / Line 18: @@
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Iacobazzi V, Palmieri F, Runswick MJ, Walker JE |title=Sequences of the human and bovine genes for the mitochondrial 2-oxoglutarate carrier. |journal=DNA Seq. |volume=3 |issue= 2 |pages= 79-88 |year= 1993 |pmid= 1457818 |doi=  }}
+*{{cite journal   |vauthors=Bisaccia F, Zara V, Capobianco L, etal |title=The formation of a disulfide cross-link between the two subunits demonstrates the dimeric structure of the mitochondrial oxoglutarate carrier |journal=Biochim. Biophys. Acta |volume=1292 |issue= 2 |pages= 281–88 |year= 1996 |pmid= 8597574 |doi=10.1016/0167-4838(95)00215-4  }}
-*{{cite journal  | author=Bisaccia F, Zara V, Capobianco L, ''et al.'' |title=The formation of a disulfide cross-link between the two subunits demonstrates the dimeric structure of the mitochondrial oxoglutarate carrier. |journal=Biochim. Biophys. Acta |volume=1292 |issue= 2 |pages= 281-88 |year= 1996 |pmid= 8597574 |doi=  }}
+*{{cite journal   |vauthors=Andersson B, Wentland MA, Ricafrente JY, etal |title=A "double adaptor" method for improved shotgun library construction |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
-*{{cite journal  | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
+*{{cite journal  | vauthors=Bisaccia F, Capobianco L, Mazzeo M, Palmieri F |title=The mitochondrial oxoglutarate carrier protein contains a disulfide bridge between intramembranous cysteines 221 and 224 |journal=FEBS Lett. |volume=392 |issue= 1 |pages= 54–8 |year= 1996 |pmid= 8769314 |doi=10.1016/0014-5793(96)00784-3  }}
-*{{cite journal  | author=Bisaccia F, Capobianco L, Mazzeo M, Palmieri F |title=The mitochondrial oxoglutarate carrier protein contains a disulfide bridge between intramembranous cysteines 221 and 224. |journal=FEBS Lett. |volume=392 |issue= 1 |pages= 54-8 |year= 1996 |pmid= 8769314 |doi=  }}
+*{{cite journal   |vauthors=Yu W, Andersson B, Worley KC, etal |title=Large-Scale Concatenation cDNA Sequencing |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=  10.1101/gr.7.4.353| pmc=139146  }}
-*{{cite journal  | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi=  }}
+*{{cite journal   |vauthors=Palmisano A, Zara V, Hönlinger A, etal |title=Targeting and assembly of the oxoglutarate carrier: general principles for biogenesis of carrier proteins of the mitochondrial inner membrane |journal=Biochem. J. |volume=333 ( Pt 1) |issue=  Pt 1|pages= 151–8 |year= 1998 |pmid= 9639574 |doi=  | pmc=1219567  }}
-*{{cite journal  | author=Palmisano A, Zara V, Hönlinger A, ''et al.'' |title=Targeting and assembly of the oxoglutarate carrier: general principles for biogenesis of carrier proteins of the mitochondrial inner membrane. |journal=Biochem. J. |volume=333 ( Pt 1) |issue=  |pages= 151-8 |year= 1998 |pmid= 9639574 |doi=  }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M }}
-*{{cite journal  | author=Piccininni S, Iacobazzi V, Lauria G, ''et al.'' |title=Assignment of the oxoglutarate carrier gene (SLC20A4) to human chromosome 17p13.3. |journal=Cytogenet. Cell Genet. |volume=83 |issue= 3-4 |pages= 256-7 |year= 1999 |pmid= 10072597 |doi=  }}
+*{{cite journal   |vauthors=Coll O, Colell A, García-Ruiz C, etal |title=Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion |journal=Hepatology |volume=38 |issue= 3 |pages= 692–702 |year= 2003 |pmid= 12939596 |doi= 10.1053/jhep.2003.50351 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Coll O, Colell A, García-Ruiz C, ''et al.'' |title=Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion. |journal=Hepatology |volume=38 |issue= 3 |pages= 692-702 |year= 2003 |pmid= 12939596 |doi= 10.1053/jhep.2003.50351 }}
+*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Kabe Y, Ohmori M, Shinouchi K, etal |title=Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier |journal=J. Biol. Chem. |volume=281 |issue= 42 |pages= 31729–35 |year= 2006 |pmid= 16920706 |doi= 10.1074/jbc.M604729200 }}
-*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
-*{{cite journal  | author=Kabe Y, Ohmori M, Shinouchi K, ''et al.'' |title=Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier. |journal=J. Biol. Chem. |volume=281 |issue= 42 |pages= 31729-35 |year= 2006 |pmid= 16920706 |doi= 10.1074/jbc.M604729200 }}
 }}
 {{refend}}
-{{membrane-protein-stub}}
 {{Membrane transport proteins}}
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+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
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+| update_citations = yes
+}}
 [[Category:Solute carrier family]]
-{{WikiDoc Sources}}
+{{membrane-protein-stub}}

SLC25A11: Difference between revisions

Latest revision as of 11:16, 30 December 2018

See also

References

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