Spina bifida diagnostic study of choice: Difference between revisions
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{{CMG}}; {{AE}} {{MMJ}} | {{CMG}}; {{AE}} {{MMJ}} | ||
== Overview == | == Overview == | ||
Ultrasound is the imaging modality of choice for characterisation of the open spina bifida spinal lesions. On two and tree-dimensional ultrasound, spina bifida is characterized by: [[Vertebral anomalies|Vertebral defect]], splayed [[Vertebral|vertebral pedicles]] and disrupted [[vertebrae]]. The [[ultrasound]] must be performed when a positive [[alpha-fetoprotein]] is detected in the triple screening test between the 15th and 20th week of pregnancy to confirm the diagnosis. | |||
== Diagnostic Study of Choice == | == Diagnostic Study of Choice == | ||
=== Study of choice === | === Study of choice === | ||
* | *Ultrasound is the imaging modality of choice for characterisation of the open spina bifida spinal lesions.<ref name="pmid24373566">{{cite journal |vauthors=Trudell AS, Odibo AO |title=Diagnosis of spina bifida on ultrasound: always termination? |journal=Best Pract Res Clin Obstet Gynaecol |volume=28 |issue=3 |pages=367–77 |date=April 2014 |pmid=24373566 |doi=10.1016/j.bpobgyn.2013.10.006 |url=}}</ref> | ||
*On | *On two and tree-dimensional ultrasound, spina bifida is characterized by:<ref name="pmid12054297">{{cite journal |vauthors=Lee W, Chaiworapongsa T, Romero R, Williams R, McNie B, Johnson A, Treadwell M, Comstock CH |title=A diagnostic approach for the evaluation of spina bifida by three-dimensional ultrasonography |journal=J Ultrasound Med |volume=21 |issue=6 |pages=619–26 |date=June 2002 |pmid=12054297 |doi= |url=}}</ref> | ||
**[[Vertebral anomalies|Vertebral defect]] | **[[Vertebral anomalies|Vertebral defect]] | ||
**Splayed [[Vertebral|vertebral pedicles]] | **Splayed [[Vertebral|vertebral pedicles]] | ||
| Line 19: | Line 15: | ||
===== Sequence of Diagnostic Studies ===== | ===== Sequence of Diagnostic Studies ===== | ||
The | The [[ultrasound]] must be performed when a positive [[alpha-fetoprotein]] is detected in the triple screening test between the 15th and 20th week of pregnancy to confirm the diagnosis.<ref name="pmid4381295">{{cite journal |vauthors=Péron FG, McCarthy JL, Guerra F |title=Further studies on corticosteroidogenesis. IV. Inhibition of utilization of biological substrates for corticoid synthesis by high calcium concentrations. Possible role of transhydrogenase in corticosteroidogenesis |journal=Biochim. Biophys. Acta |volume=117 |issue=2 |pages=450–69 |date=April 1966 |pmid=4381295 |doi= |url=}}</ref><ref name="pmid25537246">{{cite journal |vauthors=Hu Z, Liu X, Li L, Jia C, Li D, Liu R |title=[Predictive value of abnormal second-trimester maternal serum triple screening markers for adverse pregnancy outcomes] |language=Chinese |journal=Zhonghua Fu Chan Ke Za Zhi |volume=49 |issue=10 |pages=749–53 |date=October 2014 |pmid=25537246 |doi= |url=}}</ref><ref name="pmid1071059">{{cite journal |vauthors=Wyshak G, Haase JV |title=Profile of dental hygienists |journal=Dent Hyg (Chic) |volume=50 |issue=11 |pages=497–501 |date=November 1976 |pmid=1071059 |doi= |url=}}</ref><ref name="pmid3111043">{{cite journal |vauthors=Shcherbukhin VV, Khramtsov AV, Zemskov VM, Filatov AV |title=[Poisson equalization of multicomponent cytofluorograms] |language=Russian |journal=Tsitologiia |volume=29 |issue=4 |pages=497–502 |date=April 1987 |pmid=3111043 |doi= |url=}}</ref> | ||
=== | |||
==References== | ==References== | ||
Latest revision as of 17:47, 29 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
Ultrasound is the imaging modality of choice for characterisation of the open spina bifida spinal lesions. On two and tree-dimensional ultrasound, spina bifida is characterized by: Vertebral defect, splayed vertebral pedicles and disrupted vertebrae. The ultrasound must be performed when a positive alpha-fetoprotein is detected in the triple screening test between the 15th and 20th week of pregnancy to confirm the diagnosis.
Diagnostic Study of Choice
Study of choice
- Ultrasound is the imaging modality of choice for characterisation of the open spina bifida spinal lesions.[1]
- On two and tree-dimensional ultrasound, spina bifida is characterized by:[2]
- Vertebral defect
- Splayed vertebral pedicles
- Disrupted vertebrae
Sequence of Diagnostic Studies
The ultrasound must be performed when a positive alpha-fetoprotein is detected in the triple screening test between the 15th and 20th week of pregnancy to confirm the diagnosis.[3][4][5][6]
References
- ↑ Trudell AS, Odibo AO (April 2014). "Diagnosis of spina bifida on ultrasound: always termination?". Best Pract Res Clin Obstet Gynaecol. 28 (3): 367–77. doi:10.1016/j.bpobgyn.2013.10.006. PMID 24373566.
- ↑ Lee W, Chaiworapongsa T, Romero R, Williams R, McNie B, Johnson A, Treadwell M, Comstock CH (June 2002). "A diagnostic approach for the evaluation of spina bifida by three-dimensional ultrasonography". J Ultrasound Med. 21 (6): 619–26. PMID 12054297.
- ↑ Péron FG, McCarthy JL, Guerra F (April 1966). "Further studies on corticosteroidogenesis. IV. Inhibition of utilization of biological substrates for corticoid synthesis by high calcium concentrations. Possible role of transhydrogenase in corticosteroidogenesis". Biochim. Biophys. Acta. 117 (2): 450–69. PMID 4381295.
- ↑ Hu Z, Liu X, Li L, Jia C, Li D, Liu R (October 2014). "[Predictive value of abnormal second-trimester maternal serum triple screening markers for adverse pregnancy outcomes]". Zhonghua Fu Chan Ke Za Zhi (in Chinese). 49 (10): 749–53. PMID 25537246.
- ↑ Wyshak G, Haase JV (November 1976). "Profile of dental hygienists". Dent Hyg (Chic). 50 (11): 497–501. PMID 1071059.
- ↑ Shcherbukhin VV, Khramtsov AV, Zemskov VM, Filatov AV (April 1987). "[Poisson equalization of multicomponent cytofluorograms]". Tsitologiia (in Russian). 29 (4): 497–502. PMID 3111043.