Stomatitis laboratory findings: Difference between revisions
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==Laboratory findings== | ==Laboratory findings== | ||
[[History and Physical examination|History and physical examination]] are the mainstay of diagnosing stomatitis. If required laboratory findings can play an important role in diagnosing and differentiating the particular type of stomatitis. | [[History and Physical examination|History and physical examination]] are the mainstay of diagnosing stomatitis. If required, laboratory findings can play an important role in diagnosing and differentiating the particular type of stomatitis. | ||
===[[Herpetic stomatitis|Herpetic Stomatitis]]=== | ===[[Herpetic stomatitis|Herpetic Stomatitis]]=== | ||
*[[Viral culture]] | *[[Viral culture]] | ||
* | *[[Tzanck smear]] for active [[lesions]] | ||
**It | **It cannot differentiate between the various types of viruses that can cause stomatitis (i.e., [[HSV-1]], [[HSV-2]], or [[VZV]]) | ||
*[[Serology]] | *[[Serology]] | ||
*Studies using [[Immunofluorescence|immunofluorescent techniques]] | *Studies using [[Immunofluorescence|immunofluorescent techniques]] | ||
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*[[Immunofluorescence|Immunofluorescence testing]]<ref name="pmid28153136">Magliocca KR, Fitzpatrick SG (2017) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=28153136 Autoimmune Disease Manifestations in the Oral Cavity.] ''Surg Pathol Clin'' 10 (1):57-88. [http://dx.doi.org/10.1016/j.path.2016.11.001 DOI:10.1016/j.path.2016.11.001] PMID: [https://pubmed.gov/28153136 28153136]</ref> | *[[Immunofluorescence|Immunofluorescence testing]]<ref name="pmid28153136">Magliocca KR, Fitzpatrick SG (2017) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=28153136 Autoimmune Disease Manifestations in the Oral Cavity.] ''Surg Pathol Clin'' 10 (1):57-88. [http://dx.doi.org/10.1016/j.path.2016.11.001 DOI:10.1016/j.path.2016.11.001] PMID: [https://pubmed.gov/28153136 28153136]</ref> | ||
*[[Biopsy]] (showing [[hyperplasia]] of the [[stratified squamous epithelium]])<ref name="pmid23138121">{{cite journal| author=Wang H, Qiao S, Zhang X, Liu C| title=A case of pyodermatitis-pyostomatitis vegetans. | journal=Am J Med Sci | year= 2013 | volume= 345 | issue= 2 | pages= 168-71 | pmid=23138121 | doi=10.1097/MAJ.0b013e31826c5a82 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23138121 }} </ref> | *[[Biopsy]] (showing [[hyperplasia]] of the [[stratified squamous epithelium]])<ref name="pmid23138121">{{cite journal| author=Wang H, Qiao S, Zhang X, Liu C| title=A case of pyodermatitis-pyostomatitis vegetans. | journal=Am J Med Sci | year= 2013 | volume= 345 | issue= 2 | pages= 168-71 | pmid=23138121 | doi=10.1097/MAJ.0b013e31826c5a82 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23138121 }} </ref> | ||
*[[Eosinophils]], [[neutrophils]], [[plasma cells]] and [[lymphocytes]] in the connective tissue<ref name="pmid20689401">{{cite journal| author=Abellaneda C, Mascaró JM, Vázquez MG, Pablo IM, Iranzo P| title=All that glitters is not pemphigus: Pyodermatitis-pyostomatitis vegetans misdiagnosed as IgA pemphigus for 8 years. | journal=Am J Dermatopathol | year= 2011 | volume= 33 | issue= 1 | pages= e1-6 | pmid=20689401 | doi=10.1097/DAD.0b013e3181d81ecb | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20689401 }} </ref> | *[[Eosinophils]], [[neutrophils]], [[plasma cells]] and [[lymphocytes]] in the [[connective tissue]]<ref name="pmid20689401">{{cite journal| author=Abellaneda C, Mascaró JM, Vázquez MG, Pablo IM, Iranzo P| title=All that glitters is not pemphigus: Pyodermatitis-pyostomatitis vegetans misdiagnosed as IgA pemphigus for 8 years. | journal=Am J Dermatopathol | year= 2011 | volume= 33 | issue= 1 | pages= e1-6 | pmid=20689401 | doi=10.1097/DAD.0b013e3181d81ecb | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20689401 }} </ref> | ||
*Spongiotic changes<ref name="pmid20689401">{{cite journal| author=Abellaneda C, Mascaró JM, Vázquez MG, Pablo IM, Iranzo P| title=All that glitters is not pemphigus: Pyodermatitis-pyostomatitis vegetans misdiagnosed as IgA pemphigus for 8 years. | journal=Am J Dermatopathol | year= 2011 | volume= 33 | issue= 1 | pages= e1-6 | pmid=20689401 | doi=10.1097/DAD.0b013e3181d81ecb | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20689401 }} </ref> | *Spongiotic changes<ref name="pmid20689401">{{cite journal| author=Abellaneda C, Mascaró JM, Vázquez MG, Pablo IM, Iranzo P| title=All that glitters is not pemphigus: Pyodermatitis-pyostomatitis vegetans misdiagnosed as IgA pemphigus for 8 years. | journal=Am J Dermatopathol | year= 2011 | volume= 33 | issue= 1 | pages= e1-6 | pmid=20689401 | doi=10.1097/DAD.0b013e3181d81ecb | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20689401 }} </ref> | ||
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{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | |||
{{WS}} | |||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category: | [[Category:Emergency mdicine]] | ||
[[Category:Disease]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Infectious disease]] | [[Category:Infectious disease]] | ||
[[Category:Otolaryngology]] | |||
[[Category:Gastroenterology]] | |||
Latest revision as of 00:18, 30 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mehrsefat, M.D. [2], Usama Talib, BSc, MD [3]
Overview
History and physical examination are the mainstay of diagnosing stomatitis. Laboratory findings can play an important role in diagnosing and differentiating the particular type of stomatitis.
Laboratory findings
History and physical examination are the mainstay of diagnosing stomatitis. If required, laboratory findings can play an important role in diagnosing and differentiating the particular type of stomatitis.
Herpetic Stomatitis
- Viral culture
- Tzanck smear for active lesions
- Serology
- Studies using immunofluorescent techniques
- PCR
Noma or Gangrenous stomatitis
The diagnosis of Noma or gangrenous stomatitis is made by:[1]
- Culture for organisms
- Biopsy showing deep tissue involvement
Pyostomatitis vegetans
- Immunofluorescence testing[2]
- Biopsy (showing hyperplasia of the stratified squamous epithelium)[3]
- Eosinophils, neutrophils, plasma cells and lymphocytes in the connective tissue[4]
- Spongiotic changes[4]
References
- ↑ Mandell; Gouglas, Gordon; Bennett, John. Principles and Practice of Infectious Diseases. Harvard Medical School: WILEY MEDICAL. p. 383. ISBN 0-471-87643-7. Unknown parameter
|firs1t=ignored (help) - ↑ Magliocca KR, Fitzpatrick SG (2017) Autoimmune Disease Manifestations in the Oral Cavity. Surg Pathol Clin 10 (1):57-88. DOI:10.1016/j.path.2016.11.001 PMID: 28153136
- ↑ Wang H, Qiao S, Zhang X, Liu C (2013). "A case of pyodermatitis-pyostomatitis vegetans". Am J Med Sci. 345 (2): 168–71. doi:10.1097/MAJ.0b013e31826c5a82. PMID 23138121.
- ↑ 4.0 4.1 Abellaneda C, Mascaró JM, Vázquez MG, Pablo IM, Iranzo P (2011). "All that glitters is not pemphigus: Pyodermatitis-pyostomatitis vegetans misdiagnosed as IgA pemphigus for 8 years". Am J Dermatopathol. 33 (1): e1–6. doi:10.1097/DAD.0b013e3181d81ecb. PMID 20689401.