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__NOTOC__
{{Dextrocardia}}
{{Dextrocardia}}
{{CMG}}; '''Associate Editors-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.B.B.S.]] [[mailto:psingh13579@gmail.com]]; {{CZ}}; [[User:KeriShafer|Keri Shafer, M.D.]] [mailto:kshafer@bidmc.harvard.edu];  Claudia Hochberg, M.D.; '''Assistant Editor-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]] [[mailto:kfeeney@elon.edu]]
{{CMG}}; '''Associate Editors-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.B.B.S.]] [[mailto:psingh13579@gmail.com]]; {{CZ}}; [[User:KeriShafer|Keri Shafer, M.D.]] [mailto:kshafer@bidmc.harvard.edu];  Claudia Hochberg, M.D.; [[Kristin Feeney|Kristin Feeney, B.S.]] [[mailto:kfeeney@elon.edu]]; {{Jose}}
 
==Overview==
Dextrocardia is categorized as a fairly rare disease. The reported likelihood of occurrence is roughly 1 in 100 births with approximately 1 in 1,000 of these cases to have dextrocardia and situs inversus.
 
==Epidemiology==
Dextrocardia is believed to occur in approximately 1 in a 100 people, while 1 in 1,000 of these will have [[Situs Inversus]]. The most recent statistics place the incidence of stitus inversus to be 1:2500 to 1:20,000. It is significantly less common to have dextrocardia with situs solitus.
 
[[Kartagener’s syndrome]] occurs in approximately 1 in 15-25 of patients with Totalis (situs inversus with dextrocardia). Kartagener Syndrome (KS), is a rare autosomal recessive genetic disorder caused by a defect in the action of the tiny hairs (cilia) lining the respiratory tract. Specifically, it is a defect in a gene coding for left-right dynein (lrd), a key structural protein in cilia.<ref>Cleveland JC Jr, Shroyer AL, Chen AY, et al: Off-pump coronary artery bypass grafting decreases risk-adjusted mortality and morbidity. Ann Thorac Surg 2001;72: 1282-1289.</ref>


==Overview==
==Overview==
[[Dextrocardia]] is categorized as a fairly rare disease. The reported likelihood of occurrence is roughly 1 in 12,000 births.


==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Incidence===
===Incidence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
*The incidence of dextrocardia is approximately 1 in 12,000 pregnancies.<ref name="pmid17631088">{{cite journal| author=Bohun CM, Potts JE, Casey BM, Sandor GG| title=A population-based study of cardiac malformations and outcomes associated with dextrocardia. | journal=Am J Cardiol | year= 2007 | volume= 100 | issue= 2 | pages= 305-9 | pmid=17631088 | doi=10.1016/j.amjcard.2007.02.095 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17631088  }} </ref>
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
*Incidence of dextrocardia with Kartagener syndrome is approximately 1 in 60,000 pregnancies.<ref name="pmid17515466">{{cite journal| author=Kennedy MP, Omran H, Leigh MW, Dell S, Morgan L, Molina PL | display-authors=etal| title=Congenital heart disease and other heterotaxic defects in a large cohort of patients with primary ciliary dyskinesia. | journal=Circulation | year= 2007 | volume= 115 | issue= 22 | pages= 2814-21 | pmid=17515466 | doi=10.1161/CIRCULATIONAHA.106.649038 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17515466  }} </ref>


===Prevalence===
===Prevalence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
*The prevalence of dextrocardia is approximately 0.089 per 1,000 individuals.<ref name="LiuChen2019">{{cite journal|last1=Liu|first1=Yingjuan|last2=Chen|first2=Sen|last3=Zühlke|first3=Liesl|last4=Black|first4=Graeme C|last5=Choy|first5=Mun-kit|last6=Li|first6=Ningxiu|last7=Keavney|first7=Bernard D|title=Global birth prevalence of congenital heart defects 1970–2017: updated systematic review and meta-analysis of 260 studies|journal=International Journal of Epidemiology|volume=48|issue=2|year=2019|pages=455–463|issn=0300-5771|doi=10.1093/ije/dyz009}}</ref>
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
*The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
 
===Case-fatality rate/Mortality rate===
*In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
*The case-fatality rate/mortality rate of [disease name] is approximately [number range].
 
===Age===
*Patients of all age groups may develop [disease name].
*The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
*[Disease name] commonly affects individuals younger than/older than [number of years] years of age.
*[Chronic disease name] is usually first diagnosed among [age group].
*[Acute disease name] commonly affects [age group].
 
===Race===
*There is no racial predilection to [disease name].
*[Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].


===Gender===
===Gender===
*Dextrocardia affects men and women equally.<ref name="pmid31496498">{{cite journal| author=Mozayan C, Levis JT| title=ECG Diagnosis: Dextrocardia. | journal=Perm J | year= 2019 | volume= 23 | issue=  | pages=  | pmid=31496498 | doi=10.7812/TPP/18.244 | pmc=6730946 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31496498  }} </ref>
*Dextrocardia affects men and women equally.<ref name="pmid31496498">{{cite journal| author=Mozayan C, Levis JT| title=ECG Diagnosis: Dextrocardia. | journal=Perm J | year= 2019 | volume= 23 | issue=  | pages=  | pmid=31496498 | doi=10.7812/TPP/18.244 | pmc=6730946 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31496498  }} </ref>


===Region===
*The majority of [disease name] cases are reported in [geographical region].
*[Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
===Developed Countries===
===Developing Countries===


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
{{WH}}
 
{{WS}}


[[Category:Cardiology]]
[[Category:Cardiology]]

Latest revision as of 18:53, 3 July 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [[2]]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Claudia Hochberg, M.D.; Kristin Feeney, B.S. [[5]]; José Eduardo Riceto Loyola Junior, M.D.[6]

Overview

Dextrocardia is categorized as a fairly rare disease. The reported likelihood of occurrence is roughly 1 in 12,000 births.

Epidemiology and Demographics

Incidence

  • The incidence of dextrocardia is approximately 1 in 12,000 pregnancies.[1]
  • Incidence of dextrocardia with Kartagener syndrome is approximately 1 in 60,000 pregnancies.[2]

Prevalence

  • The prevalence of dextrocardia is approximately 0.089 per 1,000 individuals.[3]

Gender

  • Dextrocardia affects men and women equally.[4]


References

  1. ↑ Bohun CM, Potts JE, Casey BM, Sandor GG (2007). "A population-based study of cardiac malformations and outcomes associated with dextrocardia". Am J Cardiol. 100 (2): 305–9. doi:10.1016/j.amjcard.2007.02.095. PMID 17631088.
  2. ↑ Kennedy MP, Omran H, Leigh MW, Dell S, Morgan L, Molina PL; et al. (2007). "Congenital heart disease and other heterotaxic defects in a large cohort of patients with primary ciliary dyskinesia". Circulation. 115 (22): 2814–21. doi:10.1161/CIRCULATIONAHA.106.649038. PMID 17515466.
  3. ↑ Liu, Yingjuan; Chen, Sen; Zühlke, Liesl; Black, Graeme C; Choy, Mun-kit; Li, Ningxiu; Keavney, Bernard D (2019). "Global birth prevalence of congenital heart defects 1970–2017: updated systematic review and meta-analysis of 260 studies". International Journal of Epidemiology. 48 (2): 455–463. doi:10.1093/ije/dyz009. ISSN 0300-5771.
  4. ↑ Mozayan C, Levis JT (2019). "ECG Diagnosis: Dextrocardia". Perm J. 23. doi:10.7812/TPP/18.244. PMC 6730946 Check |pmc= value (help). PMID 31496498.
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