Spina bifida epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
The incidence of spina bifida is approximately 3.5 per 10,000 live births per year in the U.S. The prevalence of spina bifida is approximately 187 to 890 per 100,000 live births. Before 1960, the case-mortality rate of all forms of spina bifida was 90% to 88%. Now the mortality rate is approximately is 10.1%. The overall [[Ventriculoperitoneal shunt|ventriculoperitoneal]] shunt requirement rate is 33.8%. The [[paraplegia]] rate is 30.7%. The [[neurogenic bladder]] rate is 51.6%. The [[infection]] rate is 6.4% after the surgical procedure. Spina bifida is more commonly observed among preterm newborns. Spina bifida usually affects individuals of the Malays and Chinese and Indians race. Female are more commonly affected by than male. The male\male+female ratio is approximately 42%. | |||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
===Incidence=== | ===Incidence=== | ||
The incidence of spina bifida is approximately 3.5 per 10,000 live births per year in the U.S.<ref name="pmid5045772">{{cite journal |vauthors=Bass SW, Triolo AJ, Coon JM |title=Effect of DDT on the toxicity and metabolism of parathion in mice |journal=Toxicol. Appl. Pharmacol. |volume=22 |issue=4 |pages=684–93 |date=August 1972 |pmid=5045772 |doi= |url=}}</ref><ref name="pmid20878909">{{cite journal |vauthors=Parker SE, Mai CT, Canfield MA, Rickard R, Wang Y, Meyer RE, Anderson P, Mason CA, Collins JS, Kirby RS, Correa A |title=Updated National Birth Prevalence estimates for selected birth defects in the United States, 2004-2006 |journal=Birth Defects Res. Part A Clin. Mol. Teratol. |volume=88 |issue=12 |pages=1008–16 |date=December 2010 |pmid=20878909 |doi=10.1002/bdra.20735 |url=}}</ref> | |||
===Prevalence=== | ===Prevalence=== | ||
The prevalence of spina bifida is approximately 187 to 890 per 100,000 live births.<ref name="pmid5684468">{{cite journal |vauthors=Csaba G, Körösi J |title=A new antitumour agent: phenazathionium-mustard salt |journal=Neoplasma |volume=15 |issue=4 |pages=443–5 |date=1968 |pmid=5684468 |doi= |url=}}</ref> | |||
===Case-fatality rate/Mortality rate=== | ===Case-fatality rate/Mortality rate=== | ||
* | *Before 1960, the case-mortality rate of all forms of spina bifida was 90% to 88%.<ref name="pmid4937369">{{cite journal |vauthors=Lorber J |title=Results of treatment of myelomeningocele. An analysis of 524 unselected cases, with special reference to possible selection for treatment |journal=Dev Med Child Neurol |volume=13 |issue=3 |pages=279–303 |date=June 1971 |pmid=4937369 |doi= |url=}}</ref> | ||
*The | *In all patients with neural tube defects including spina bifida:<ref name="pmid5141554">{{cite journal |vauthors=Carreras y Matas M |title=[Strabismic sensorial perversions as a cause of secondary vertical deviation] |language=Spanish; Castilian |journal=Rev Esp Otoneurooftalmol Neurocir |volume=29 |issue=172 |pages=361–3 |date=1971 |pmid=5141554 |doi= |url=}}</ref> | ||
**Now the mortality rate is approximately is 10.1%. | |||
**The overall [[Ventriculoperitoneal shunt|ventriculoperitoneal]] shunt requirement rate is 33.8%. | |||
**The [[paraplegia]] rate is 30.7%. | |||
**The [[neurogenic bladder]] rate is 51.6%. | |||
**The [[infection]] rate is 6.4% after the surgical procedure. | |||
* | |||
===Age=== | ===Age=== | ||
Spina bifida is more commonly observed among preterm newborns.<ref name="pmid4898641">{{cite journal |vauthors=Bannur BB, Purandare GM |title=Microbial production of L-lysine |journal=Hindustan Antibiot Bull |volume=11 |issue=3 |pages=191–205 |date=February 1969 |pmid=4898641 |doi= |url=}}</ref> | |||
===Race=== | ===Race=== | ||
* | *Spina bifida usually affects individuals of the Malays and Chinese and Indians race.<ref name="pmid5684468" /> | ||
===Gender=== | ===Gender=== | ||
* | *Female are more commonly affected by than male. The male\male+female ratio is approximately 42%.<ref name="pmid5045772">{{cite journal |vauthors=Bass SW, Triolo AJ, Coon JM |title=Effect of DDT on the toxicity and metabolism of parathion in mice |journal=Toxicol. Appl. Pharmacol. |volume=22 |issue=4 |pages=684–93 |date=August 1972 |pmid=5045772 |doi= |url=}}</ref> | ||
=== | |||
=== | |||
==References== | ==References== | ||
Latest revision as of 19:09, 28 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
The incidence of spina bifida is approximately 3.5 per 10,000 live births per year in the U.S. The prevalence of spina bifida is approximately 187 to 890 per 100,000 live births. Before 1960, the case-mortality rate of all forms of spina bifida was 90% to 88%. Now the mortality rate is approximately is 10.1%. The overall ventriculoperitoneal shunt requirement rate is 33.8%. The paraplegia rate is 30.7%. The neurogenic bladder rate is 51.6%. The infection rate is 6.4% after the surgical procedure. Spina bifida is more commonly observed among preterm newborns. Spina bifida usually affects individuals of the Malays and Chinese and Indians race. Female are more commonly affected by than male. The male\male+female ratio is approximately 42%.
Epidemiology and Demographics
Incidence
The incidence of spina bifida is approximately 3.5 per 10,000 live births per year in the U.S.[1][2]
Prevalence
The prevalence of spina bifida is approximately 187 to 890 per 100,000 live births.[3]
Case-fatality rate/Mortality rate
- Before 1960, the case-mortality rate of all forms of spina bifida was 90% to 88%.[4]
- In all patients with neural tube defects including spina bifida:[5]
- Now the mortality rate is approximately is 10.1%.
- The overall ventriculoperitoneal shunt requirement rate is 33.8%.
- The paraplegia rate is 30.7%.
- The neurogenic bladder rate is 51.6%.
- The infection rate is 6.4% after the surgical procedure.
Age
Spina bifida is more commonly observed among preterm newborns.[6]
Race
- Spina bifida usually affects individuals of the Malays and Chinese and Indians race.[3]
Gender
- Female are more commonly affected by than male. The male\male+female ratio is approximately 42%.[1]
References
- ↑ 1.0 1.1 Bass SW, Triolo AJ, Coon JM (August 1972). "Effect of DDT on the toxicity and metabolism of parathion in mice". Toxicol. Appl. Pharmacol. 22 (4): 684–93. PMID 5045772.
- ↑ Parker SE, Mai CT, Canfield MA, Rickard R, Wang Y, Meyer RE, Anderson P, Mason CA, Collins JS, Kirby RS, Correa A (December 2010). "Updated National Birth Prevalence estimates for selected birth defects in the United States, 2004-2006". Birth Defects Res. Part A Clin. Mol. Teratol. 88 (12): 1008–16. doi:10.1002/bdra.20735. PMID 20878909.
- ↑ 3.0 3.1 Csaba G, Körösi J (1968). "A new antitumour agent: phenazathionium-mustard salt". Neoplasma. 15 (4): 443–5. PMID 5684468.
- ↑ Lorber J (June 1971). "Results of treatment of myelomeningocele. An analysis of 524 unselected cases, with special reference to possible selection for treatment". Dev Med Child Neurol. 13 (3): 279–303. PMID 4937369.
- ↑ Carreras y Matas M (1971). "[Strabismic sensorial perversions as a cause of secondary vertical deviation]". Rev Esp Otoneurooftalmol Neurocir (in Spanish; Castilian). 29 (172): 361–3. PMID 5141554.
- ↑ Bannur BB, Purandare GM (February 1969). "Microbial production of L-lysine". Hindustan Antibiot Bull. 11 (3): 191–205. PMID 4898641.