Autoimmune retinopathy classification: Difference between revisions
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==Overview== | ==Overview== | ||
Autoimmune retinopathy (AIR) can be broadly classified into two main categories: non-paraneoplastic AIR (npAIR) and paraneoplastic AIR. Paraneoplastic AIR is most frequently associated with [[small-cell lung cancer]], followed by breast and gynecologic (uterine, ovarian and cervical) carcinoma. Other cancer associations include hematological, prostate, colon and lymphomas. Non-paraneoplastic AIR, which is the most prevalent form of AIR, is seen in the absence of neoplasms. AIR can also be a secondary complication of other conditions such as [[retinitis pigmentosa]], ocular trauma, birdshot retinopathy, acute zonal occult outer retinopathy (AZOOR), or multiple evanescent white dot syndrome (MEWDS). | |||
==Classification== | ==Classification== | ||
*Autoimmune retinopathy (AIR) can be broadly classified into two main categories: non-paraneoplastic AIR (npAIR) and [[Paraneoplastic syndrome|paraneoplastic]] AIR. | |||
*Paraneoplastic AIR is most frequently associated with [[small-cell lung cancer]], followed by breast and gynecologic (uterine, ovarian and cervical) carcinoma. Other cancer associations include hematological, prostate, colon and [[lymphomas]]. | |||
*Non-paraneoplastic AIR, which is the most prevalent form of AIR, is seen in the absence of neoplasms. <ref name="pmid29340169">{{cite journal| author=Canamary AM, Takahashi WY, Sallum JMF| title=Autoimmune retinopathy: A Review. | journal=Int J Retina Vitreous | year= 2018 | volume= 4 | issue= | pages= 1 | pmid=29340169 | doi=10.1186/s40942-017-0104-9 | pmc=5759752 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29340169 }}</ref> | |||
*AIR can also be a secondary complication of other conditions such as [[retinitis pigmentosa]], ocular trauma, birdshot retinopathy, acute zonal occult outer retinopathy (AZOOR), or multiple evanescent white dot syndrome (MEWDS). <ref name="pmid18408929">{{cite journal| author=Heckenlively JR, Ferreyra HA| title=Autoimmune retinopathy: a review and summary. | journal=Semin Immunopathol | year= 2008 | volume= 30 | issue= 2 | pages= 127-34 | pmid=18408929 | doi=10.1007/s00281-008-0114-7 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18408929 }}</ref><br /> | |||
{| class="wikitable" | |||
|+Autoimmune retinopathy and associated cell dysfunction | |||
!Type of Autoimmune Retinopathy | |||
!Cellular dysfunction | |||
|- | |||
|Non-paraneoplastic | |||
|Cones or rods or both | |||
|- | |||
|Paraneoplastic | |||
|Cones or rods or both | |||
|- | |||
|Cancer associated retinopathy | |||
|Cones and rods | |||
|- | |||
|Melanoma associated retinopathy | |||
|Rods, antibodies against bipolar cells | |||
|} | |||
* | |||
==References== | ==References== |
Latest revision as of 02:54, 18 July 2022
Autoimmune retinopathy Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S
Overview
Autoimmune retinopathy (AIR) can be broadly classified into two main categories: non-paraneoplastic AIR (npAIR) and paraneoplastic AIR. Paraneoplastic AIR is most frequently associated with small-cell lung cancer, followed by breast and gynecologic (uterine, ovarian and cervical) carcinoma. Other cancer associations include hematological, prostate, colon and lymphomas. Non-paraneoplastic AIR, which is the most prevalent form of AIR, is seen in the absence of neoplasms. AIR can also be a secondary complication of other conditions such as retinitis pigmentosa, ocular trauma, birdshot retinopathy, acute zonal occult outer retinopathy (AZOOR), or multiple evanescent white dot syndrome (MEWDS).
Classification
- Autoimmune retinopathy (AIR) can be broadly classified into two main categories: non-paraneoplastic AIR (npAIR) and paraneoplastic AIR.
- Paraneoplastic AIR is most frequently associated with small-cell lung cancer, followed by breast and gynecologic (uterine, ovarian and cervical) carcinoma. Other cancer associations include hematological, prostate, colon and lymphomas.
- Non-paraneoplastic AIR, which is the most prevalent form of AIR, is seen in the absence of neoplasms. [1]
- AIR can also be a secondary complication of other conditions such as retinitis pigmentosa, ocular trauma, birdshot retinopathy, acute zonal occult outer retinopathy (AZOOR), or multiple evanescent white dot syndrome (MEWDS). [2]
Type of Autoimmune Retinopathy | Cellular dysfunction |
---|---|
Non-paraneoplastic | Cones or rods or both |
Paraneoplastic | Cones or rods or both |
Cancer associated retinopathy | Cones and rods |
Melanoma associated retinopathy | Rods, antibodies against bipolar cells |
References
- ↑ Canamary AM, Takahashi WY, Sallum JMF (2018). "Autoimmune retinopathy: A Review". Int J Retina Vitreous. 4: 1. doi:10.1186/s40942-017-0104-9. PMC 5759752. PMID 29340169.
- ↑ Heckenlively JR, Ferreyra HA (2008). "Autoimmune retinopathy: a review and summary". Semin Immunopathol. 30 (2): 127–34. doi:10.1007/s00281-008-0114-7. PMID 18408929.