Chronic renal failure epidemiology and demographics: Difference between revisions

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The incidence and prevalence of chronic renal failure varies enormously depending on the level of affluence of the country. Developed countries have a higher incident rate of treated end-stage renal failure, whereas the emerging countries have very low incident rates. There are currently about one million patients undergoing [[dialysis]] worldwide, with an incidence of 0.25 million patients each year.
The incidence and prevalence of chronic renal failure varies enormously depending on the level of affluence of the country. Developed countries have a higher incident rate of treated end-stage renal failure, whereas the emerging countries have very low incident rates. There are currently about one million patients undergoing [[dialysis]] worldwide, with an incidence of 0.25 million patients each year.


==Epidemiology of in United States==
==Epidemiology of CKD in United States==
* The incidence of chronic renal failure in the US is 330 per million people.
* In 2003, the Third National Health Survey reported a prevalence of CKD in the general population (age 20 or older) of 11% (19.2 million).
* More than 10% of people aged 20 years or older have [[Chronic kidney disease]] (CKD).
* When divided by CKD stage<ref name="pmid12500213">{{cite journal| author=Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS| title=Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. | journal=Am J Kidney Dis | year= 2003 |volume= 41 | issue= 1 | pages= 1-12 |pmid=12500213|doi=10.1053/ajkd.2003.50007 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12500213 }} </ref>
* More than 35% of patients aged 20 years or older with [[Diabetes]] have CKD.
** 3.3% of participants had stage 1
* More than 20% of patients aged 20 years or older with [[Hypertension]] have CKD.
** 3.0% had stage 2
* Men with CKD are 50% more likely than women to progress to [[Chronic renal failure]].
** 4.3% had stage 3
** 0.2% had stage 4
** 0.2% had stage 5
** ESRD.
* The study also showed that beyond the classical risk factors notably diabetes and hypertension, age was a separate correlate with CKD prevalence with 11% of people older than 65 years of age having stage 3 or worse CKD in the absence of both diabetes and hypertension.  
* Overall, 26% of the general population above 65 years of age has some form of kidney disease manifested by an eGFR <60 mL/min/1.73 m<sup>2</sup>. Ethnicity was found to be related to CKD and ESRD prevalence.  
* ESRD was slightly more prevalent in non-Hispanic blacks than in non-Hispanic whites.  
* In contrast, less severe stages of CKD were more common among whites, and least common among Mexican Americans.<ref name="pmid12500213">{{cite journal| author=Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS| title=Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. | journal=Am J Kidney Dis | year= 2003 | volume= 41 | issue= 1 | pages= 1-12 |pmid=12500213|doi=10.1053/ajkd.2003.50007 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12500213 }} </ref>


==Epidemiology in Developing countries==
==Epidemiology of CKD worldwide==
* The prevalence of CRF varies from being 100 per million in the populations of Sub-Saharan Africa and India, to 400 per million in Latin America and 600 per million in Saudi Arabia.
* Worldwide, CKD has been on rise especially over the past decade.
* The majority of experts agree that a CRF prevalence of 150 per million people is the average incidence in developing countries.
* In developed countries, the rise in incidence is expected to continue at an annual rate of around 5-8%.  
 
* What is thought to play a role in the continued increase in incidence is the aging of the general population and increase in the incidence of type II diabetes.  
==Age==
* Incidence of chronic renal failure is greater among adults older than 65 years.
 
==Impact of gender==
* Although the prevalence of chronic renal failure in men and women does not differ significantly, it is relatively higher in females.
 
==Ethinicity==
* African Americans were 4 times more likely to develop CRF than whites in 2007. Hispanics have 1.5 times higher rates than non-Hispanic whites.


==References==
==References==
{{reflist|2}}
{{reflist|1}}
1. {{cite web | url    = http://www.cdc.gov/diabetes/pubs/factsheets/kidney.htm  | title  = National chronic kidney disease Fact Sheet 2010
| last1  =  | first1 =  | last2  =  | first2 =  | date  =  | work  =  | publisher  = Center of Disease Control and Prevention}}
 


[[Category:Nephrology]]
[[Category:Nephrology]]





Latest revision as of 21:51, 31 July 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]

Overview

The incidence and prevalence of chronic renal failure varies enormously depending on the level of affluence of the country. Developed countries have a higher incident rate of treated end-stage renal failure, whereas the emerging countries have very low incident rates. There are currently about one million patients undergoing dialysis worldwide, with an incidence of 0.25 million patients each year.

Epidemiology of CKD in United States

  • In 2003, the Third National Health Survey reported a prevalence of CKD in the general population (age 20 or older) of 11% (19.2 million).
  • When divided by CKD stage[1]
    • 3.3% of participants had stage 1
    • 3.0% had stage 2
    • 4.3% had stage 3
    • 0.2% had stage 4
    • 0.2% had stage 5
    • ESRD.
  • The study also showed that beyond the classical risk factors notably diabetes and hypertension, age was a separate correlate with CKD prevalence with 11% of people older than 65 years of age having stage 3 or worse CKD in the absence of both diabetes and hypertension.
  • Overall, 26% of the general population above 65 years of age has some form of kidney disease manifested by an eGFR <60 mL/min/1.73 m2. Ethnicity was found to be related to CKD and ESRD prevalence.
  • ESRD was slightly more prevalent in non-Hispanic blacks than in non-Hispanic whites.
  • In contrast, less severe stages of CKD were more common among whites, and least common among Mexican Americans.[1]

Epidemiology of CKD worldwide

  • Worldwide, CKD has been on rise especially over the past decade.
  • In developed countries, the rise in incidence is expected to continue at an annual rate of around 5-8%.
  • What is thought to play a role in the continued increase in incidence is the aging of the general population and increase in the incidence of type II diabetes.

References

  1. 1.0 1.1 Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS (2003). "Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey". Am J Kidney Dis. 41 (1): 1–12. doi:10.1053/ajkd.2003.50007. PMID 12500213.


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