EIF5: Difference between revisions
Jump to navigation
Jump to search
m (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}})) |
m (Bot: HTTP→HTTPS) |
||
| Line 1: | Line 1: | ||
< | {{Infobox_gene}} | ||
{{ | '''Eukaryotic translation initiation factor 5''' is a [[protein]] that in humans is encoded by the ''EIF5'' [[gene]].<ref name="pmid8663286">{{cite journal | vauthors = Si K, Das K, Maitra U | title = Characterization of multiple mRNAs that encode mammalian translation initiation factor 5 (eIF-5) | journal = J Biol Chem | volume = 271 | issue = 28 | pages = 16934–8 |date=Aug 1996 | pmid = 8663286 | pmc = | doi =10.1074/jbc.271.28.16934 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: EIF5 eukaryotic translation initiation factor 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1983| accessdate = }}</ref> | ||
| | |||
| | |||
| | |||
}} | |||
EIF5 is a [[GTPase-activating protein]].<ref name="pmid11092890">{{cite journal |vauthors=Das S, Ghosh R, Maitra U |title=Eukaryotic translation initiation factor 5 functions as a GTPase-activating protein |journal=J. Biol. Chem. |volume=276 |issue=9 |pages=6720–6 |date=March 2001 |pmid=11092890 |doi=10.1074/jbc.M008863200 |url=http://www.jbc.org/cgi/pmidlookup?view=long&pmid=11092890}}</ref> | |||
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. --> | <!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. --> | ||
| Line 57: | Line 11: | ||
==References== | ==References== | ||
{{reflist | {{reflist}} | ||
==External links== | ==External links== | ||
| Line 66: | Line 20: | ||
{{PBB_Further_reading | {{PBB_Further_reading | ||
| citations = | | citations = | ||
*{{cite journal | | *{{cite journal | vauthors=Das S, Maiti T, Das K, Maitra U |title=Specific interaction of eukaryotic translation initiation factor 5 (eIF5) with the beta-subunit of eIF2. |journal=J. Biol. Chem. |volume=272 |issue= 50 |pages= 31712–8 |year= 1998 |pmid= 9395514 |doi=10.1074/jbc.272.50.31712 }} | ||
*{{cite journal | | *{{cite journal | vauthors=Bandyopadhyay A, Maitra U |title=Cloning and characterization of the p42 subunit of mammalian translation initiation factor 3 (eIF3): demonstration that eIF3 interacts with eIF5 in mammalian cells. |journal=Nucleic Acids Res. |volume=27 |issue= 5 |pages= 1331–7 |year= 1999 |pmid= 9973622 |doi=10.1093/nar/27.5.1331 | pmc=148320 }} | ||
*{{cite journal | | *{{cite journal | vauthors=Das S, Maitra U |title=Mutational analysis of mammalian translation initiation factor 5 (eIF5): role of interaction between the beta subunit of eIF2 and eIF5 in eIF5 function in vitro and in vivo. |journal=Mol. Cell. Biol. |volume=20 |issue= 11 |pages= 3942–50 |year= 2000 |pmid= 10805737 |doi=10.1128/MCB.20.11.3942-3950.2000 | pmc=85746 }} | ||
*{{cite journal | | *{{cite journal | vauthors=Choi SK, Olsen DS, Roll-Mecak A |title=Physical and functional interaction between the eukaryotic orthologs of prokaryotic translation initiation factors IF1 and IF2. |journal=Mol. Cell. Biol. |volume=20 |issue= 19 |pages= 7183–91 |year= 2000 |pmid= 10982835 |doi=10.1128/MCB.20.19.7183-7191.2000 | pmc=86272 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal | vauthors=Das S, Ghosh R, Maitra U |title=Eukaryotic translation initiation factor 5 functions as a GTPase-activating protein. |journal=J. Biol. Chem. |volume=276 |issue= 9 |pages= 6720–6 |year= 2001 |pmid= 11092890 |doi= 10.1074/jbc.M008863200 }} | ||
*{{cite journal | | *{{cite journal | vauthors=Wiemann S, Weil B, Wellenreuther R |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R | pmc=311072 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal | vauthors=Asano K, Shalev A, Phan L |title=Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation. |journal=EMBO J. |volume=20 |issue= 9 |pages= 2326–37 |year= 2001 |pmid= 11331597 |doi= 10.1093/emboj/20.9.2326 | pmc=125443 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal | vauthors=Majumdar R, Bandyopadhyay A, Deng H, Maitra U |title=Phosphorylation of mammalian translation initiation factor 5 (eIF5) in vitro and in vivo. |journal=Nucleic Acids Res. |volume=30 |issue= 5 |pages= 1154–62 |year= 2002 |pmid= 11861906 |doi=10.1093/nar/30.5.1154 | pmc=101238 }} | ||
*{{cite journal | | *{{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal | vauthors=Marintchev A, Kolupaeva VG, Pestova TV, Wagner G |title=Mapping the binding interface between human eukaryotic initiation factors 1A and 5B: a new interaction between old partners. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 4 |pages= 1535–40 |year= 2003 |pmid= 12569173 |doi= 10.1073/pnas.0437845100 | pmc=149867 }} | ||
*{{cite journal | | *{{cite journal | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal | vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal | vauthors=Homma MK, Wada I, Suzuki T |title=CK2 phosphorylation of eukaryotic translation initiation factor 5 potentiates cell cycle progression. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 43 |pages= 15688–93 |year= 2005 |pmid= 16227438 |doi= 10.1073/pnas.0506791102 | pmc=1266118 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal | vauthors=Conte MR, Kelly G, Babon J |title=Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors. |journal=Biochemistry |volume=45 |issue= 14 |pages= 4550–8 |year= 2006 |pmid= 16584190 |doi= 10.1021/bi052387u |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal | vauthors=Bieniossek C, Schütz P, Bumann M |title=The crystal structure of the carboxy-terminal domain of human translation initiation factor eIF5. |journal=J. Mol. Biol. |volume=360 |issue= 2 |pages= 457–65 |year= 2006 |pmid= 16781736 |doi= 10.1016/j.jmb.2006.05.021 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal | vauthors=Olsen JV, Blagoev B, Gnad F |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |display-authors=etal}} | ||
}} | }} | ||
{{refend}} | {{refend}} | ||
{{PDB Gallery|geneid=1983}} | |||
{{Initiation factors}} | {{Initiation factors}} | ||
{{ | <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. --> | ||
{{ | {{PBB_Controls | ||
| update_page = yes | |||
| require_manual_inspection = no | |||
| update_protein_box = yes | |||
| update_summary = yes | |||
| update_citations = yes | |||
}} | |||
{{gene-14-stub}} | |||
Latest revision as of 00:26, 31 August 2017
| VALUE_ERROR (nil) | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Aliases | |||||||
| External IDs | GeneCards: [1] | ||||||
| Orthologs | |||||||
| Species | Human | Mouse | |||||
| Entrez |
|
| |||||
| Ensembl |
|
| |||||
| UniProt |
|
| |||||
| RefSeq (mRNA) |
|
| |||||
| RefSeq (protein) |
|
| |||||
| Location (UCSC) | n/a | n/a | |||||
| PubMed search | n/a | n/a | |||||
| Wikidata | |||||||
| |||||||
Eukaryotic translation initiation factor 5 is a protein that in humans is encoded by the EIF5 gene.[1][2]
EIF5 is a GTPase-activating protein.[3]
References
- ↑ Si K, Das K, Maitra U (Aug 1996). "Characterization of multiple mRNAs that encode mammalian translation initiation factor 5 (eIF-5)". J Biol Chem. 271 (28): 16934–8. doi:10.1074/jbc.271.28.16934. PMID 8663286.
- ↑ "Entrez Gene: EIF5 eukaryotic translation initiation factor 5".
- ↑ Das S, Ghosh R, Maitra U (March 2001). "Eukaryotic translation initiation factor 5 functions as a GTPase-activating protein". J. Biol. Chem. 276 (9): 6720–6. doi:10.1074/jbc.M008863200. PMID 11092890.
External links
- Cap-dependent translation initiation from Nature Reviews Microbiology. A good image and overview of the function of initiation factors
Further reading
- Das S, Maiti T, Das K, Maitra U (1998). "Specific interaction of eukaryotic translation initiation factor 5 (eIF5) with the beta-subunit of eIF2". J. Biol. Chem. 272 (50): 31712–8. doi:10.1074/jbc.272.50.31712. PMID 9395514.
- Bandyopadhyay A, Maitra U (1999). "Cloning and characterization of the p42 subunit of mammalian translation initiation factor 3 (eIF3): demonstration that eIF3 interacts with eIF5 in mammalian cells". Nucleic Acids Res. 27 (5): 1331–7. doi:10.1093/nar/27.5.1331. PMC 148320. PMID 9973622.
- Das S, Maitra U (2000). "Mutational analysis of mammalian translation initiation factor 5 (eIF5): role of interaction between the beta subunit of eIF2 and eIF5 in eIF5 function in vitro and in vivo". Mol. Cell. Biol. 20 (11): 3942–50. doi:10.1128/MCB.20.11.3942-3950.2000. PMC 85746. PMID 10805737.
- Choi SK, Olsen DS, Roll-Mecak A, et al. (2000). "Physical and functional interaction between the eukaryotic orthologs of prokaryotic translation initiation factors IF1 and IF2". Mol. Cell. Biol. 20 (19): 7183–91. doi:10.1128/MCB.20.19.7183-7191.2000. PMC 86272. PMID 10982835.
- Das S, Ghosh R, Maitra U (2001). "Eukaryotic translation initiation factor 5 functions as a GTPase-activating protein". J. Biol. Chem. 276 (9): 6720–6. doi:10.1074/jbc.M008863200. PMID 11092890.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- Asano K, Shalev A, Phan L, et al. (2001). "Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation". EMBO J. 20 (9): 2326–37. doi:10.1093/emboj/20.9.2326. PMC 125443. PMID 11331597.
- Majumdar R, Bandyopadhyay A, Deng H, Maitra U (2002). "Phosphorylation of mammalian translation initiation factor 5 (eIF5) in vitro and in vivo". Nucleic Acids Res. 30 (5): 1154–62. doi:10.1093/nar/30.5.1154. PMC 101238. PMID 11861906.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Marintchev A, Kolupaeva VG, Pestova TV, Wagner G (2003). "Mapping the binding interface between human eukaryotic initiation factors 1A and 5B: a new interaction between old partners". Proc. Natl. Acad. Sci. U.S.A. 100 (4): 1535–40. doi:10.1073/pnas.0437845100. PMC 149867. PMID 12569173.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Homma MK, Wada I, Suzuki T, et al. (2005). "CK2 phosphorylation of eukaryotic translation initiation factor 5 potentiates cell cycle progression". Proc. Natl. Acad. Sci. U.S.A. 102 (43): 15688–93. doi:10.1073/pnas.0506791102. PMC 1266118. PMID 16227438.
- Conte MR, Kelly G, Babon J, et al. (2006). "Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors". Biochemistry. 45 (14): 4550–8. doi:10.1021/bi052387u. PMID 16584190.
- Bieniossek C, Schütz P, Bumann M, et al. (2006). "The crystal structure of the carboxy-terminal domain of human translation initiation factor eIF5". J. Mol. Biol. 360 (2): 457–65. doi:10.1016/j.jmb.2006.05.021. PMID 16781736.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
 | This article on a gene on human chromosome 14 is a stub. You can help Wikipedia by expanding it. |