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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Mitochondrial 70kDa heat shock protein (mtHsp70), also known as mortalin,''' is a [[protein]] that in humans is encoded by the ''HSPA9'' [[gene]].<ref name="pmid7684501">{{cite journal |vauthors=Domanico SZ, DeNagel DC, Dahlseid JN, Green JM, Pierce SK | title = Cloning of the gene encoding peptide-binding protein 74 shows that it is a new member of the heat shock protein 70 family | journal = Mol Cell Biol | volume = 13 | issue = 6 | pages = 3598–610 | date = Jun 1993 | pmid = 7684501 | pmc = 359829 | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: HSPA9 heat shock 70kDa protein 9 (mortalin)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3313| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Heat shock 70kDa protein 9 (mortalin)
| HGNCid = 5244
| Symbol = HSPA9
| AltSymbols =; CSA; GRP75; HSPA9B; MGC4500; MOT; MOT2; MTHSP75; PBP74; mot-2
| OMIM = 600548
| ECnumber = 
| Homologene = 39452
| MGIid = 96245
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0051082 |text = unfolded protein binding}}
| Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005739 |text = mitochondrion}} {{GNF_GO|id=GO:0009986 |text = cell surface}}
| Process = {{GNF_GO|id=GO:0006457 |text = protein folding}} {{GNF_GO|id=GO:0006611 |text = protein export from nucleus}} {{GNF_GO|id=GO:0006916 |text = anti-apoptosis}} {{GNF_GO|id=GO:0006986 |text = response to unfolded protein}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 3313
    | Hs_Ensembl = 
    | Hs_RefseqProtein = NP_004125
    | Hs_RefseqmRNA = NM_004134
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 
    | Hs_GenLoc_start = 
    | Hs_GenLoc_end = 
    | Hs_Uniprot = 
    | Mm_EntrezGene = 15526
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = NM_010481
    | Mm_RefseqProtein = NP_034611
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
    | Mm_Uniprot = 
  }}
}}
'''Heat shock 70kDa protein 9 (mortalin)''', also known as '''HSPA9''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: HSPA9 heat shock 70kDa protein 9 (mortalin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3313| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein plays a role in the control of cell proliferation. It may also act as a chaperone.<ref name="entrez"/>
{{PBB_Summary
 
| section_title =
== Interactions ==
| summary_text = The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein plays a role in the control of cell proliferation. It may also act as a chaperone.<ref name="entrez">{{cite web | title = Entrez Gene: HSPA9 heat shock 70kDa protein 9 (mortalin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3313| accessdate = }}</ref>
 
}}
HSPA9 has been shown to [[Protein-protein interaction|interact]] with [[FGF1]]<ref name=pmid10510314>{{cite journal |vauthors=Mizukoshi E, Suzuki M, Loupatov A, Uruno T, Hayashi H, Misono T, Kaul SC, Wadhwa R, Imamura T | title = Fibroblast growth factor-1 interacts with the glucose-regulated protein GRP75/mortalin | journal = Biochem. J. | volume = 343 Pt 2 | issue = 2 | pages = 461–6 | date = Oct 1999 | pmid = 10510314 | pmc = 1220575 | doi = 10.1042/0264-6021:3430461 }}</ref> and [[P53]].<ref name=pmid11900485>{{cite journal |vauthors=Wadhwa R, Yaguchi T, Hasan MK, Mitsui Y, Reddel RR, Kaul SC | title = Hsp70 family member, mot-2/mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein | journal = Exp. Cell Res. | volume = 274 | issue = 2 | pages = 246–53 | date = Apr 2002 | pmid = 11900485 | doi = 10.1006/excr.2002.5468 }}</ref>
 
== References ==
{{reflist}}


==References==
{{reflist|2}}
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
*{{cite journal |vauthors=Kaul SC, Taira K, Pereira-Smith OM, Wadhwa R | title = Mortalin: present and prospective | journal = Exp. Gerontol. | volume = 37 | issue = 10–11 | pages = 1157–64 | year = 2003 | pmid = 12470827 | doi = 10.1016/S0531-5565(02)00135-3 }}
| citations =
*{{cite journal |vauthors=Yaguchi T, Aida S, Kaul SC, Wadhwa R | title = Involvement of mortalin in cellular senescence from the perspective of its mitochondrial import, chaperone, and oxidative stress management functions | journal = Ann. N. Y. Acad. Sci. | volume = 1100 | issue =  | pages = 306–11 | year = 2007 | pmid = 17460192 | doi = 10.1196/annals.1395.032 }}
*{{cite journal | author=Kaul SC, Taira K, Pereira-Smith OM, Wadhwa R |title=Mortalin: present and prospective. |journal=Exp. Gerontol. |volume=37 |issue= 10-11 |pages= 1157-64 |year= 2003 |pmid= 12470827 |doi= }}
*{{cite journal |vauthors=Hochstrasser DF, Frutiger S, Paquet N, Bairoch A, Ravier F, Pasquali C, Sanchez JC, Tissot JD, Bjellqvist B, Vargas R | title = Human liver protein map: a reference database established by microsequencing and gel comparison | journal = Electrophoresis | volume = 13 | issue = 12 | pages = 992–1001 | year = 1993 | pmid = 1286669 | doi = 10.1002/elps.11501301201 }}
*{{cite journal | author=Yaguchi T, Aida S, Kaul SC, Wadhwa R |title=Involvement of mortalin in cellular senescence from the perspective of its mitochondrial import, chaperone, and oxidative stress management functions. |journal=Ann. N. Y. Acad. Sci. |volume=1100 |issue=  |pages= 306-11 |year= 2007 |pmid= 17460192 |doi= 10.1196/annals.1395.032 }}
*{{cite journal |vauthors=Kaul SC, Wadhwa R, Matsuda Y, Hensler PJ, Pereira-Smith OM, Komatsu Y, Mitsui Y | title = Mouse and human chromosomal assignments of mortalin, a novel member of the murine hsp70 family of proteins | journal = FEBS Lett. | volume = 361 | issue = 2–3 | pages = 269–72 | year = 1995 | pmid = 7698336 | doi = 10.1016/0014-5793(95)00177-B }}
*{{cite journal | author=Hochstrasser DF, Frutiger S, Paquet N, ''et al.'' |title=Human liver protein map: a reference database established by microsequencing and gel comparison. |journal=Electrophoresis |volume=13 |issue= 12 |pages= 992-1001 |year= 1993 |pmid= 1286669 |doi= }}
*{{cite journal |vauthors=Bhattacharyya T, Karnezis AN, Murphy SP, Hoang T, Freeman BC, Phillips B, Morimoto RI | title = Cloning and subcellular localization of human mitochondrial hsp70 | journal = J. Biol. Chem. | volume = 270 | issue = 4 | pages = 1705–10 | year = 1995 | pmid = 7829505 | doi = 10.1074/jbc.270.4.1705 }}
*{{cite journal | author=Domanico SZ, DeNagel DC, Dahlseid JN, ''et al.'' |title=Cloning of the gene encoding peptide-binding protein 74 shows that it is a new member of the heat shock protein 70 family. |journal=Mol. Cell. Biol. |volume=13 |issue= 6 |pages= 3598-610 |year= 1993 |pmid= 7684501 |doi= }}
*{{cite journal |vauthors=Furlini G, Vignoli M, Re MC, Gibellini D, Ramazzotti E, Zauli G, La Placa M | title = Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein | journal = J. Gen. Virol. | volume = 75 | issue = 1 | pages = 193–9 | year = 1994 | pmid = 7906708 | doi = 10.1099/0022-1317-75-1-193 }}
*{{cite journal | author=Kaul SC, Wadhwa R, Matsuda Y, ''et al.'' |title=Mouse and human chromosomal assignments of mortalin, a novel member of the murine hsp70 family of proteins. |journal=FEBS Lett. |volume=361 |issue= 2-3 |pages= 269-72 |year= 1995 |pmid= 7698336 |doi= }}
*{{cite journal |vauthors=Matoba R, Okubo K, Hori N, Fukushima A, Matsubara K | title = The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression | journal = Gene | volume = 146 | issue = 2 | pages = 199–207 | year = 1994 | pmid = 8076819 | doi = 10.1016/0378-1119(94)90293-3 }}
*{{cite journal | author=Bhattacharyya T, Karnezis AN, Murphy SP, ''et al.'' |title=Cloning and subcellular localization of human mitochondrial hsp70. |journal=J. Biol. Chem. |volume=270 |issue= 4 |pages= 1705-10 |year= 1995 |pmid= 7829505 |doi= }}
*{{cite journal |vauthors=Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | year = 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
*{{cite journal | author=Furlini G, Vignoli M, Re MC, ''et al.'' |title=Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein. |journal=J. Gen. Virol. |volume=75 ( Pt 1) |issue= |pages= 193-9 |year= 1994 |pmid= 7906708 |doi= }}
*{{cite journal |vauthors=Hughes GJ, Frutiger S, Paquet N, Pasquali C, Sanchez JC, Tissot JD, Bairoch A, Appel RD, Hochstrasser DF | title = Human liver protein map: update 1993 | journal = Electrophoresis | volume = 14 | issue = 11 | pages = 1216–22 | year = 1994 | pmid = 8313870 | doi = 10.1002/elps.11501401181 }}
*{{cite journal | author=Matoba R, Okubo K, Hori N, ''et al.'' |title=The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression. |journal=Gene |volume=146 |issue= 2 |pages= 199-207 |year= 1994 |pmid= 8076819 |doi= }}
*{{cite journal |vauthors=Ji H, Reid GE, Moritz RL, Eddes JS, Burgess AW, Simpson RJ | title = A two-dimensional gel database of human colon carcinoma proteins | journal = Electrophoresis | volume = 18 | issue = 3–4 | pages = 605–13 | year = 1997 | pmid = 9150948 | doi = 10.1002/elps.1150180344 }}
*{{cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi= }}
*{{cite journal |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | year = 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
*{{cite journal | author=Hughes GJ, Frutiger S, Paquet N, ''et al.'' |title=Human liver protein map: update 1993. |journal=Electrophoresis |volume=14 |issue= 11 |pages= 1216-22 |year= 1994 |pmid= 8313870 |doi= }}
*{{cite journal |vauthors=Mizukoshi E, Suzuki M, Loupatov A, Uruno T, Hayashi H, Misono T, Kaul SC, Wadhwa R, Imamura T | title = Fibroblast growth factor-1 interacts with the glucose-regulated protein GRP75/mortalin | journal = Biochem. J. | volume = 343 Pt 2 | issue = 2 | pages = 461–6 | year = 1999 | pmid = 10510314 | pmc = 1220575 | doi = 10.1042/0264-6021:3430461 }}
*{{cite journal | author=Ji H, Reid GE, Moritz RL, ''et al.'' |title=A two-dimensional gel database of human colon carcinoma proteins. |journal=Electrophoresis |volume=18 |issue= 3-4 |pages= 605-13 |year= 1997 |pmid= 9150948 |doi= 10.1002/elps.1150180344 }}
*{{cite journal |vauthors=O'Keeffe B, Fong Y, Chen D, Zhou S, Zhou Q | title = Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription | journal = J. Biol. Chem. | volume = 275 | issue = 1 | pages = 279–87 | year = 2000 | pmid = 10617616 | doi = 10.1074/jbc.275.1.279 }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi= }}
*{{cite journal |vauthors=Kaula SC, Reddelb RR, Sugiharac T, Mitsuia Y, Wadhwac R | title = Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2 | journal = FEBS Lett. | volume = 474 | issue = 2–3 | pages = 159–64 | year = 2000 | pmid = 10838077 | doi = 10.1016/S0014-5793(00)01594-5 }}
*{{cite journal | author=Mizukoshi E, Suzuki M, Loupatov A, ''et al.'' |title=Fibroblast growth factor-1 interacts with the glucose-regulated protein GRP75/mortalin. |journal=Biochem. J. |volume=343 Pt 2 |issue= |pages= 461-6 |year= 1999 |pmid= 10510314 |doi= }}
*{{cite journal |vauthors=Agostini I, Popov S, Li J, Dubrovsky L, Hao T, Bukrinsky M | title = Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex | journal = Exp. Cell Res. | volume = 259 | issue = 2 | pages = 398–403 | year = 2000 | pmid = 10964507 | doi = 10.1006/excr.2000.4992 }}
*{{cite journal | author=O'Keeffe B, Fong Y, Chen D, ''et al.'' |title=Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription. |journal=J. Biol. Chem. |volume=275 |issue= 1 |pages= 279-87 |year= 2000 |pmid= 10617616 |doi= }}
*{{cite journal |vauthors=Xie H, Hu Z, Chyna B, Horrigan SK, Westbrook CA | title = Human mortalin (HSPA9): a candidate for the myeloid leukemia tumor suppressor gene on 5q31 | journal = Leukemia | volume = 14 | issue = 12 | pages = 2128–34 | year = 2001 | pmid = 11187902 | doi = 10.1038/sj.leu.2401935 }}
*{{cite journal | author=Kaula SC, Reddelb RR, Sugiharac T, ''et al.'' |title=Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2. |journal=FEBS Lett. |volume=474 |issue= 2-3 |pages= 159-64 |year= 2000 |pmid= 10838077 |doi= }}
*{{cite journal |vauthors=Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI | title = Directed proteomic analysis of the human nucleolus | journal = Curr. Biol. | volume = 12 | issue = 1 | pages = 1–11 | year = 2002 | pmid = 11790298 | doi = 10.1016/S0960-9822(01)00650-9 }}
*{{cite journal | author=Agostini I, Popov S, Li J, ''et al.'' |title=Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex. |journal=Exp. Cell Res. |volume=259 |issue= 2 |pages= 398-403 |year= 2000 |pmid= 10964507 |doi= 10.1006/excr.2000.4992 }}
*{{cite journal |vauthors=Carette J, Lehnert S, Chow TY | title = Implication of PBP74/mortalin/GRP75 in the radio-adaptive response | journal = Int. J. Radiat. Biol. | volume = 78 | issue = 3 | pages = 183–90 | year = 2002 | pmid = 11869473 | doi = 10.1080/09553000110097208 }}
*{{cite journal | author=Xie H, Hu Z, Chyna B, ''et al.'' |title=Human mortalin (HSPA9): a candidate for the myeloid leukemia tumor suppressor gene on 5q31. |journal=Leukemia |volume=14 |issue= 12 |pages= 2128-34 |year= 2001 |pmid= 11187902 |doi= }}
*{{cite journal |vauthors=Wadhwa R, Yaguchi T, Hasan MK, Mitsui Y, Reddel RR, Kaul SC | title = Hsp70 family member, mot-2/mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein | journal = Exp. Cell Res. | volume = 274 | issue = 2 | pages = 246–53 | year = 2002 | pmid = 11900485 | doi = 10.1006/excr.2002.5468 }}
*{{cite journal | author=Andersen JS, Lyon CE, Fox AH, ''et al.'' |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1-11 |year= 2002 |pmid= 11790298 |doi= }}
*{{cite journal | author=Carette J, Lehnert S, Chow TY |title=Implication of PBP74/mortalin/GRP75 in the radio-adaptive response. |journal=Int. J. Radiat. Biol. |volume=78 |issue= 3 |pages= 183-90 |year= 2002 |pmid= 11869473 |doi= 10.1080/09553000110097208 }}
*{{cite journal  | author=Wadhwa R, Yaguchi T, Hasan MK, ''et al.'' |title=Hsp70 family member, mot-2/mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein. |journal=Exp. Cell Res. |volume=274 |issue= 2 |pages= 246-53 |year= 2002 |pmid= 11900485 |doi= 10.1006/excr.2002.5468 }}
}}
{{refend}}
{{refend}}
== External links ==
* {{MeshName|HSPA9+protein,+human}}
{{Chaperones}}
[[Category:Heat shock proteins]]
[[Category:Molecular chaperones]]
[[Category:Mitochondrial proteins]]


{{protein-stub}}
{{protein-stub}}
{{WikiDoc Sources}}

Latest revision as of 15:58, 18 October 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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n/a

Ensembl

n/a

n/a

UniProt

n/a

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Mitochondrial 70kDa heat shock protein (mtHsp70), also known as mortalin, is a protein that in humans is encoded by the HSPA9 gene.[1][2]

Function

The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein plays a role in the control of cell proliferation. It may also act as a chaperone.[2]

Interactions

HSPA9 has been shown to interact with FGF1[3] and P53.[4]

References

  1. ↑ Domanico SZ, DeNagel DC, Dahlseid JN, Green JM, Pierce SK (Jun 1993). "Cloning of the gene encoding peptide-binding protein 74 shows that it is a new member of the heat shock protein 70 family". Mol Cell Biol. 13 (6): 3598–610. PMC 359829. PMID 7684501.
  2. ↑ 2.0 2.1 "Entrez Gene: HSPA9 heat shock 70kDa protein 9 (mortalin)".
  3. ↑ Mizukoshi E, Suzuki M, Loupatov A, Uruno T, Hayashi H, Misono T, Kaul SC, Wadhwa R, Imamura T (Oct 1999). "Fibroblast growth factor-1 interacts with the glucose-regulated protein GRP75/mortalin". Biochem. J. 343 Pt 2 (2): 461–6. doi:10.1042/0264-6021:3430461. PMC 1220575. PMID 10510314.
  4. ↑ Wadhwa R, Yaguchi T, Hasan MK, Mitsui Y, Reddel RR, Kaul SC (Apr 2002). "Hsp70 family member, mot-2/mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein". Exp. Cell Res. 274 (2): 246–53. doi:10.1006/excr.2002.5468. PMID 11900485.

Further reading

  • Kaul SC, Taira K, Pereira-Smith OM, Wadhwa R (2003). "Mortalin: present and prospective". Exp. Gerontol. 37 (10–11): 1157–64. doi:10.1016/S0531-5565(02)00135-3. PMID 12470827.
  • Yaguchi T, Aida S, Kaul SC, Wadhwa R (2007). "Involvement of mortalin in cellular senescence from the perspective of its mitochondrial import, chaperone, and oxidative stress management functions". Ann. N. Y. Acad. Sci. 1100: 306–11. doi:10.1196/annals.1395.032. PMID 17460192.
  • Hochstrasser DF, Frutiger S, Paquet N, Bairoch A, Ravier F, Pasquali C, Sanchez JC, Tissot JD, Bjellqvist B, Vargas R (1993). "Human liver protein map: a reference database established by microsequencing and gel comparison". Electrophoresis. 13 (12): 992–1001. doi:10.1002/elps.11501301201. PMID 1286669.
  • Kaul SC, Wadhwa R, Matsuda Y, Hensler PJ, Pereira-Smith OM, Komatsu Y, Mitsui Y (1995). "Mouse and human chromosomal assignments of mortalin, a novel member of the murine hsp70 family of proteins". FEBS Lett. 361 (2–3): 269–72. doi:10.1016/0014-5793(95)00177-B. PMID 7698336.
  • Bhattacharyya T, Karnezis AN, Murphy SP, Hoang T, Freeman BC, Phillips B, Morimoto RI (1995). "Cloning and subcellular localization of human mitochondrial hsp70". J. Biol. Chem. 270 (4): 1705–10. doi:10.1074/jbc.270.4.1705. PMID 7829505.
  • Furlini G, Vignoli M, Re MC, Gibellini D, Ramazzotti E, Zauli G, La Placa M (1994). "Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein". J. Gen. Virol. 75 (1): 193–9. doi:10.1099/0022-1317-75-1-193. PMID 7906708.
  • Matoba R, Okubo K, Hori N, Fukushima A, Matsubara K (1994). "The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression". Gene. 146 (2): 199–207. doi:10.1016/0378-1119(94)90293-3. PMID 8076819.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Hughes GJ, Frutiger S, Paquet N, Pasquali C, Sanchez JC, Tissot JD, Bairoch A, Appel RD, Hochstrasser DF (1994). "Human liver protein map: update 1993". Electrophoresis. 14 (11): 1216–22. doi:10.1002/elps.11501401181. PMID 8313870.
  • Ji H, Reid GE, Moritz RL, Eddes JS, Burgess AW, Simpson RJ (1997). "A two-dimensional gel database of human colon carcinoma proteins". Electrophoresis. 18 (3–4): 605–13. doi:10.1002/elps.1150180344. PMID 9150948.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Mizukoshi E, Suzuki M, Loupatov A, Uruno T, Hayashi H, Misono T, Kaul SC, Wadhwa R, Imamura T (1999). "Fibroblast growth factor-1 interacts with the glucose-regulated protein GRP75/mortalin". Biochem. J. 343 Pt 2 (2): 461–6. doi:10.1042/0264-6021:3430461. PMC 1220575. PMID 10510314.
  • O'Keeffe B, Fong Y, Chen D, Zhou S, Zhou Q (2000). "Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription". J. Biol. Chem. 275 (1): 279–87. doi:10.1074/jbc.275.1.279. PMID 10617616.
  • Kaula SC, Reddelb RR, Sugiharac T, Mitsuia Y, Wadhwac R (2000). "Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2". FEBS Lett. 474 (2–3): 159–64. doi:10.1016/S0014-5793(00)01594-5. PMID 10838077.
  • Agostini I, Popov S, Li J, Dubrovsky L, Hao T, Bukrinsky M (2000). "Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex". Exp. Cell Res. 259 (2): 398–403. doi:10.1006/excr.2000.4992. PMID 10964507.
  • Xie H, Hu Z, Chyna B, Horrigan SK, Westbrook CA (2001). "Human mortalin (HSPA9): a candidate for the myeloid leukemia tumor suppressor gene on 5q31". Leukemia. 14 (12): 2128–34. doi:10.1038/sj.leu.2401935. PMID 11187902.
  • Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
  • Carette J, Lehnert S, Chow TY (2002). "Implication of PBP74/mortalin/GRP75 in the radio-adaptive response". Int. J. Radiat. Biol. 78 (3): 183–90. doi:10.1080/09553000110097208. PMID 11869473.
  • Wadhwa R, Yaguchi T, Hasan MK, Mitsui Y, Reddel RR, Kaul SC (2002). "Hsp70 family member, mot-2/mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein". Exp. Cell Res. 274 (2): 246–53. doi:10.1006/excr.2002.5468. PMID 11900485.

External links


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