Syntaxin binding protein 2: Difference between revisions

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Latest revision as of 20:24, 13 May 2018

Syntaxin-binding protein 2 is a protein that in humans is encoded by the STXBP2 gene.^[1]^[2]

References

↑ Ziegler SF, Mortrud MT, Swartz AR, Baker E, Sutherland GR, Burmeister M, Mulligan JT (Feb 1997). "Molecular characterization of a nonneuronal human UNC18 homolog". Genomics. 37 (1): 19–23. doi:10.1006/geno.1996.0515. PMID 8921365.
↑ "Entrez Gene: STXBP2 syntaxin binding protein 2".

Ibaraki K, Horikawa HP, Morita T, et al. (1995). "Identification of four different forms of syntaxin 3". Biochem. Biophys. Res. Commun. 211 (3): 997–1005. doi:10.1006/bbrc.1995.1910. PMID 7598732.
Hata Y, Südhof TC (1995). "A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic". J. Biol. Chem. 270 (22): 13022–8. doi:10.1074/jbc.270.22.13022. PMID 7768895.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Tellam JT, Macaulay SL, McIntosh S, et al. (1997). "Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4". J. Biol. Chem. 272 (10): 6179–86. doi:10.1074/jbc.272.10.6179. PMID 9045631.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Riento K, Galli T, Jansson S, et al. (1999). "Interaction of Munc-18-2 with syntaxin 3 controls the association of apical SNAREs in epithelial cells". J. Cell Sci. 111 (17): 2681–8. PMID 9701566.
Riento K, Kauppi M, Keranen S, Olkkonen VM (2000). "Munc18-2, a functional partner of syntaxin 3, controls apical membrane trafficking in epithelial cells". J. Biol. Chem. 275 (18): 13476–83. doi:10.1074/jbc.275.18.13476. PMID 10788461.
Pellizzoni L, Baccon J, Rappsilber J, et al. (2002). "Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component". J. Biol. Chem. 277 (9): 7540–5. doi:10.1074/jbc.M110141200. PMID 11748230.
Baccon J, Pellizzoni L, Rappsilber J, et al. (2002). "Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex". J. Biol. Chem. 277 (35): 31957–62. doi:10.1074/jbc.M203478200. PMID 12065586.
Kauppi M, Wohlfahrt G, Olkkonen VM (2003). "Analysis of the Munc18b-syntaxin binding interface. Use of a mutant Munc18b to dissect the functions of syntaxins 2 and 3". J. Biol. Chem. 277 (46): 43973–9. doi:10.1074/jbc.M208315200. PMID 12198139.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Martin-Verdeaux S, Pombo I, Iannascoli B, et al. (2003). "Evidence of a role for Munc18-2 and microtubules in mast cell granule exocytosis". J. Cell Sci. 116 (Pt 2): 325–34. doi:10.1242/jcs.00216. PMID 12482918.
Houng A, Polgar J, Reed GL (2003). "Munc18-syntaxin complexes and exocytosis in human platelets". J. Biol. Chem. 278 (22): 19627–33. doi:10.1074/jbc.M212465200. PMID 12649283.
Schraw TD, Lemons PP, Dean WL, Whiteheart SW (2003). "A role for Sec1/Munc18 proteins in platelet exocytosis". Biochem. J. 374 (Pt 1): 207–17. doi:10.1042/BJ20030610. PMC 1223584. PMID 12773094.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

[pmid8921365-1] Ziegler SF, Mortrud MT, Swartz AR, Baker E, Sutherland GR, Burmeister M, Mulligan JT (Feb 1997). "Molecular characterization of a nonneuronal human UNC18 homolog". Genomics. 37 (1): 19–23. doi:10.1006/geno.1996.0515. PMID 8921365.

[entrez-2] "Entrez Gene: STXBP2 syntaxin binding protein 2".

[1]

[2]

@@ Line 1: / Line 1: @@
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- | image =
- | image_source =
- | PDB =
- | Name = Syntaxin binding protein 2
- | HGNCid = 11445
- | Symbol = STXBP2
- | AltSymbols =; Hunc18b; MUNC18-2; UNC18-2; UNC18B; pp10122
- | OMIM = 601717
- | ECnumber =
- | Homologene = 55530
- | MGIid = 107370
- | Function = {{GNF_GO|id=GO:0030347 |text = syntaxin-2 binding}} {{GNF_GO|id=GO:0030348 |text = syntaxin-3 binding}}
- | Component = {{GNF_GO|id=GO:0005575 |text = cellular_component}}
- | Process = {{GNF_GO|id=GO:0006886 |text = intracellular protein transport}} {{GNF_GO|id=GO:0006904 |text = vesicle docking during exocytosis}} {{GNF_GO|id=GO:0016192 |text = vesicle-mediated transport}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 6813
-    | Hs_Ensembl = ENSG00000076944
-    | Hs_RefseqProtein = NP_008880
-    | Hs_RefseqmRNA = NM_006949
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 19
-    | Hs_GenLoc_start = 7608010
-    | Hs_GenLoc_end = 7618758
-    | Hs_Uniprot = Q15833
-    | Mm_EntrezGene = 20911
-    | Mm_Ensembl = ENSMUSG00000004626
-    | Mm_RefseqmRNA = NM_011503
-    | Mm_RefseqProtein = NP_035633
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 8
-    | Mm_GenLoc_start = 3631139
-    | Mm_GenLoc_end = 3642794
-    | Mm_Uniprot = Q548T0
-  }}
-}}
-'''Syntaxin binding protein 2''', also known as '''STXBP2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: STXBP2 syntaxin binding protein 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6813| accessdate = }}</ref>
+{{Infobox_gene}}
+'''Syntaxin-binding protein 2''' is a [[protein]] that in humans is encoded by the ''STXBP2'' [[gene]].<ref name="pmid8921365">{{cite journal |vauthors=Ziegler SF, Mortrud MT, Swartz AR, Baker E, Sutherland GR, Burmeister M, Mulligan JT | title = Molecular characterization of a nonneuronal human UNC18 homolog | journal = Genomics | volume = 37 | issue = 1 | pages = 19–23 |date=Feb 1997 | pmid = 8921365 | pmc =  | doi = 10.1006/geno.1996.0515 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: STXBP2 syntaxin binding protein 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6813| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
 {{PBB_Summary
@@ Line 54: / Line 9: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Ibaraki K, Horikawa HP, Morita T, ''et al.'' |title=Identification of four different forms of syntaxin 3. |journal=Biochem. Biophys. Res. Commun. |volume=211 |issue= 3 |pages= 997-1005 |year= 1995 |pmid= 7598732 |doi= 10.1006/bbrc.1995.1910 }}
+*{{cite journal   |vauthors=Ibaraki K, Horikawa HP, Morita T, etal |title=Identification of four different forms of syntaxin 3. |journal=Biochem. Biophys. Res. Commun. |volume=211 |issue= 3 |pages= 997–1005 |year= 1995 |pmid= 7598732 |doi= 10.1006/bbrc.1995.1910 }}
-*{{cite journal  | author=Hata Y, Südhof TC |title=A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic. |journal=J. Biol. Chem. |volume=270 |issue= 22 |pages= 13022-8 |year= 1995 |pmid= 7768895 |doi=  }}
+*{{cite journal  |vauthors=Hata Y, Südhof TC |title=A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic. |journal=J. Biol. Chem. |volume=270 |issue= 22 |pages= 13022–8 |year= 1995 |pmid= 7768895 |doi=  10.1074/jbc.270.22.13022}}
-*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
+*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
-*{{cite journal  | author=Ziegler SF, Mortrud MT, Swartz AR, ''et al.'' |title=Molecular characterization of a nonneuronal human UNC18 homolog. |journal=Genomics |volume=37 |issue= 1 |pages= 19-23 |year= 1997 |pmid= 8921365 |doi= 10.1006/geno.1996.0515 }}
+*{{cite journal   |vauthors=Tellam JT, Macaulay SL, McIntosh S, etal |title=Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4. |journal=J. Biol. Chem. |volume=272 |issue= 10 |pages= 6179–86 |year= 1997 |pmid= 9045631 |doi=10.1074/jbc.272.10.6179  }}
-*{{cite journal  | author=Tellam JT, Macaulay SL, McIntosh S, ''et al.'' |title=Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4. |journal=J. Biol. Chem. |volume=272 |issue= 10 |pages= 6179-86 |year= 1997 |pmid= 9045631 |doi=  }}
+*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  }}
-*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
+*{{cite journal   |vauthors=Riento K, Galli T, Jansson S, etal |title=Interaction of Munc-18-2 with syntaxin 3 controls the association of apical SNAREs in epithelial cells. |journal=J. Cell Sci. |volume=111 |issue=  17|pages= 2681–8 |year= 1999 |pmid= 9701566 |doi=  }}
-*{{cite journal  | author=Riento K, Galli T, Jansson S, ''et al.'' |title=Interaction of Munc-18-2 with syntaxin 3 controls the association of apical SNAREs in epithelial cells. |journal=J. Cell. Sci. |volume=111 ( Pt 17) |issue=  |pages= 2681-8 |year= 1999 |pmid= 9701566 |doi=  }}
+*{{cite journal  |vauthors=Riento K, Kauppi M, Keranen S, Olkkonen VM |title=Munc18-2, a functional partner of syntaxin 3, controls apical membrane trafficking in epithelial cells. |journal=J. Biol. Chem. |volume=275 |issue= 18 |pages= 13476–83 |year= 2000 |pmid= 10788461 |doi=10.1074/jbc.275.18.13476  }}
-*{{cite journal  | author=Riento K, Kauppi M, Keranen S, Olkkonen VM |title=Munc18-2, a functional partner of syntaxin 3, controls apical membrane trafficking in epithelial cells. |journal=J. Biol. Chem. |volume=275 |issue= 18 |pages= 13476-83 |year= 2000 |pmid= 10788461 |doi=  }}
+*{{cite journal   |vauthors=Pellizzoni L, Baccon J, Rappsilber J, etal |title=Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component. |journal=J. Biol. Chem. |volume=277 |issue= 9 |pages= 7540–5 |year= 2002 |pmid= 11748230 |doi= 10.1074/jbc.M110141200 }}
-*{{cite journal  | author=Pellizzoni L, Baccon J, Rappsilber J, ''et al.'' |title=Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component. |journal=J. Biol. Chem. |volume=277 |issue= 9 |pages= 7540-5 |year= 2002 |pmid= 11748230 |doi= 10.1074/jbc.M110141200 }}
+*{{cite journal   |vauthors=Baccon J, Pellizzoni L, Rappsilber J, etal |title=Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex. |journal=J. Biol. Chem. |volume=277 |issue= 35 |pages= 31957–62 |year= 2002 |pmid= 12065586 |doi= 10.1074/jbc.M203478200 }}
-*{{cite journal  | author=Baccon J, Pellizzoni L, Rappsilber J, ''et al.'' |title=Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex. |journal=J. Biol. Chem. |volume=277 |issue= 35 |pages= 31957-62 |year= 2002 |pmid= 12065586 |doi= 10.1074/jbc.M203478200 }}
+*{{cite journal  |vauthors=Kauppi M, Wohlfahrt G, Olkkonen VM |title=Analysis of the Munc18b-syntaxin binding interface. Use of a mutant Munc18b to dissect the functions of syntaxins 2 and 3. |journal=J. Biol. Chem. |volume=277 |issue= 46 |pages= 43973–9 |year= 2003 |pmid= 12198139 |doi= 10.1074/jbc.M208315200 }}
-*{{cite journal  | author=Kauppi M, Wohlfahrt G, Olkkonen VM |title=Analysis of the Munc18b-syntaxin binding interface. Use of a mutant Munc18b to dissect the functions of syntaxins 2 and 3. |journal=J. Biol. Chem. |volume=277 |issue= 46 |pages= 43973-9 |year= 2003 |pmid= 12198139 |doi= 10.1074/jbc.M208315200 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Martin-Verdeaux S, Pombo I, Iannascoli B, etal |title=Evidence of a role for Munc18-2 and microtubules in mast cell granule exocytosis. |journal=J. Cell Sci. |volume=116 |issue= Pt 2 |pages= 325–34 |year= 2003 |pmid= 12482918 |doi=10.1242/jcs.00216  }}
-*{{cite journal  | author=Martin-Verdeaux S, Pombo I, Iannascoli B, ''et al.'' |title=Evidence of a role for Munc18-2 and microtubules in mast cell granule exocytosis. |journal=J. Cell. Sci. |volume=116 |issue= Pt 2 |pages= 325-34 |year= 2003 |pmid= 12482918 |doi=  }}
+*{{cite journal  |vauthors=Houng A, Polgar J, Reed GL |title=Munc18-syntaxin complexes and exocytosis in human platelets. |journal=J. Biol. Chem. |volume=278 |issue= 22 |pages= 19627–33 |year= 2003 |pmid= 12649283 |doi= 10.1074/jbc.M212465200 }}
-*{{cite journal  | author=Houng A, Polgar J, Reed GL |title=Munc18-syntaxin complexes and exocytosis in human platelets. |journal=J. Biol. Chem. |volume=278 |issue= 22 |pages= 19627-33 |year= 2003 |pmid= 12649283 |doi= 10.1074/jbc.M212465200 }}
+*{{cite journal  |vauthors=Schraw TD, Lemons PP, Dean WL, Whiteheart SW |title=A role for Sec1/Munc18 proteins in platelet exocytosis. |journal=Biochem. J. |volume=374 |issue= Pt 1 |pages= 207–17 |year= 2003 |pmid= 12773094 |doi= 10.1042/BJ20030610  | pmc=1223584 }}
-*{{cite journal  | author=Schraw TD, Lemons PP, Dean WL, Whiteheart SW |title=A role for Sec1/Munc18 proteins in platelet exocytosis. |journal=Biochem. J. |volume=374 |issue= Pt 1 |pages= 207-17 |year= 2003 |pmid= 12773094 |doi= 10.1042/BJ20030610 }}
+*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
-*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
 }}
 {{refend}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
+{{Vesicular transport proteins}}
 {{gene-19-stub}}

Syntaxin binding protein 2: Difference between revisions

Latest revision as of 20:24, 13 May 2018

References

Further reading

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