TPM4: Difference between revisions

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Latest revision as of 05:21, 16 March 2018

Tropomyosin alpha-4 chain is a protein that in humans is encoded by the TPM4 gene.^[1]^[2]

References

↑ Wilton SD, Lim L, Dorosz SD, Gunn HC, Eyre HJ, Callen DF, Laing NG (Jul 1996). "Assignment of the human alpha-tropomyosin gene TPM4 to band 19p13.1 by fluorescence in situ hybridization". Cytogenet Cell Genet. 72 (4): 294–6. doi:10.1159/000134206. PMID 8641132.
↑ "Entrez Gene: TPM4 tropomyosin 4".

Rasmussen HH, van Damme J, Puype M, et al. (1993). "Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes". Electrophoresis. 13 (12): 960–9. doi:10.1002/elps.11501301199. PMID 1286667.
MacLeod AR, Talbot K, Smillie LB, Houlker C (1987). "Characterization of a cDNA defining a gene family encoding TM30p1, a human fibroblast tropomyosin". J. Mol. Biol. 194 (1): 1–10. doi:10.1016/0022-2836(87)90710-8. PMID 3612796.
MacLeod AR, Houlker C, Reinach FC, et al. (1986). "A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism". Proc. Natl. Acad. Sci. U.S.A. 82 (23): 7835–9. doi:10.1073/pnas.82.23.7835. PMC 390864. PMID 3865200.
Lawrence B, Perez-Atayde A, Hibbard MK, et al. (2000). "TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors". Am. J. Pathol. 157 (2): 377–84. doi:10.1016/S0002-9440(10)64550-6. PMC 1850130. PMID 10934142.
Meech SJ, McGavran L, Odom LF, et al. (2001). "Unusual childhood extramedullary hematologic malignancy with natural killer cell properties that contains tropomyosin 4--anaplastic lymphoma kinase gene fusion". Blood. 98 (4): 1209–16. doi:10.1182/blood.V98.4.1209. PMID 11493472.
Yi J, Kloeker S, Jensen CC, et al. (2002). "Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers". J. Biol. Chem. 277 (11): 9580–9. doi:10.1074/jbc.M106922200. PMID 11782456.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Lin KT, Lu RM, Tarn WY (2004). "The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo". Mol. Cell. Biol. 24 (20): 9176–85. doi:10.1128/MCB.24.20.9176-9185.2004. PMC 517884. PMID 15456888.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Bruneel A, Labas V, Mailloux A, et al. (2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876–84. doi:10.1002/pmic.200401239. PMID 16130169.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

[pmid8641132-1] Wilton SD, Lim L, Dorosz SD, Gunn HC, Eyre HJ, Callen DF, Laing NG (Jul 1996). "Assignment of the human alpha-tropomyosin gene TPM4 to band 19p13.1 by fluorescence in situ hybridization". Cytogenet Cell Genet. 72 (4): 294–6. doi:10.1159/000134206. PMID 8641132.

[entrez-2] "Entrez Gene: TPM4 tropomyosin 4".

[1]

[2]

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+'''[[Tropomyosin]] alpha-4 chain''' is a [[protein]] that in humans is encoded by the ''TPM4'' [[gene]].<ref name="pmid8641132">{{cite journal | vauthors = Wilton SD, Lim L, Dorosz SD, Gunn HC, Eyre HJ, Callen DF, Laing NG | title = Assignment of the human alpha-tropomyosin gene TPM4 to band 19p13.1 by fluorescence in situ hybridization | journal = Cytogenet Cell Genet | volume = 72 | issue = 4 | pages = 294–6 |date=Jul 1996 | pmid = 8641132 | pmc =  | doi =10.1159/000134206  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TPM4 tropomyosin 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7171| accessdate = }}</ref>
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- | image =
- | image_source =
- | PDB =
- | Name = Tropomyosin 4
- | HGNCid = 12013
- | Symbol = TPM4
- | AltSymbols =;
- | OMIM = 600317
- | ECnumber =
- | Homologene = 74286
- | MGIid = 2449202
- | GeneAtlas_image1 = PBB_GE_TPM4_212481_s_at_tn.png
- | GeneAtlas_image2 = PBB_GE_TPM4_209344_at_tn.png
- | Function = {{GNF_GO|id=GO:0003779 |text = actin binding}} {{GNF_GO|id=GO:0008307 |text = structural constituent of muscle}}
- | Component = {{GNF_GO|id=GO:0005856 |text = cytoskeleton}} {{GNF_GO|id=GO:0005862 |text = muscle thin filament tropomyosin}}
- | Process = {{GNF_GO|id=GO:0006928 |text = cell motility}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 7171
-    | Hs_Ensembl = ENSG00000167460
-    | Hs_RefseqProtein = NP_003281
-    | Hs_RefseqmRNA = NM_003290
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 19
-    | Hs_GenLoc_start = 16039348
-    | Hs_GenLoc_end = 16074813
-    | Hs_Uniprot = P67936
-    | Mm_EntrezGene = 326618
-    | Mm_Ensembl = ENSMUSG00000031799
-    | Mm_RefseqmRNA = NM_001001491
-    | Mm_RefseqProtein = NP_001001491
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 8
-    | Mm_GenLoc_start = 75064275
-    | Mm_GenLoc_end = 75082123
-    | Mm_Uniprot = Q6IRU2
-  }}
-}}
-'''Tropomyosin 4''', also known as '''TPM4''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TPM4 tropomyosin 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7171| accessdate = }}</ref>
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@@ Line 56: / Line 10: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Rasmussen HH, van Damme J, Puype M, ''et al.'' |title=Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. |journal=Electrophoresis |volume=13 |issue= 12 |pages= 960-9 |year= 1993 |pmid= 1286667 |doi=  }}
+*{{cite journal   |vauthors=Rasmussen HH, van Damme J, Puype M, etal |title=Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. |journal=Electrophoresis |volume=13 |issue= 12 |pages= 960–9 |year= 1993 |pmid= 1286667 |doi=10.1002/elps.11501301199  }}
-*{{cite journal  | author=MacLeod AR, Talbot K, Smillie LB, Houlker C |title=Characterization of a cDNA defining a gene family encoding TM30p1, a human fibroblast tropomyosin. |journal=J. Mol. Biol. |volume=194 |issue= 1 |pages= 1-10 |year= 1987 |pmid= 3612796 |doi=  }}
+*{{cite journal  | vauthors=MacLeod AR, Talbot K, Smillie LB, Houlker C |title=Characterization of a cDNA defining a gene family encoding TM30p1, a human fibroblast tropomyosin. |journal=J. Mol. Biol. |volume=194 |issue= 1 |pages= 1–10 |year= 1987 |pmid= 3612796 |doi=10.1016/0022-2836(87)90710-8  }}
-*{{cite journal  | author=MacLeod AR, Houlker C, Reinach FC, ''et al.'' |title=A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=82 |issue= 23 |pages= 7835-9 |year= 1986 |pmid= 3865200 |doi=  }}
+*{{cite journal   |vauthors=MacLeod AR, Houlker C, Reinach FC, etal |title=A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=82 |issue= 23 |pages= 7835–9 |year= 1986 |pmid= 3865200 |doi=10.1073/pnas.82.23.7835  | pmc=390864  }}
-*{{cite journal  | author=Wilton SD, Lim L, Dorosz SD, ''et al.'' |title=Assignment of the human alpha-tropomyosin gene TPM4 to band 19p13.1 by fluorescence in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=72 |issue= 4 |pages= 294-6 |year= 1996 |pmid= 8641132 |doi=  }}
+*{{cite journal   |vauthors=Lawrence B, Perez-Atayde A, Hibbard MK, etal |title=TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors. |journal=Am. J. Pathol. |volume=157 |issue= 2 |pages= 377–84 |year= 2000 |pmid= 10934142 |doi=  10.1016/S0002-9440(10)64550-6| pmc=1850130  }}
-*{{cite journal  | author=Lawrence B, Perez-Atayde A, Hibbard MK, ''et al.'' |title=TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors. |journal=Am. J. Pathol. |volume=157 |issue= 2 |pages= 377-84 |year= 2000 |pmid= 10934142 |doi=  }}
+*{{cite journal   |vauthors=Meech SJ, McGavran L, Odom LF, etal |title=Unusual childhood extramedullary hematologic malignancy with natural killer cell properties that contains tropomyosin 4--anaplastic lymphoma kinase gene fusion |journal=Blood |volume=98 |issue= 4 |pages= 1209–16 |year= 2001 |pmid= 11493472 |doi=10.1182/blood.V98.4.1209  }}
-*{{cite journal  | author=Meech SJ, McGavran L, Odom LF, ''et al.'' |title=Unusual childhood extramedullary hematologic malignancy with natural killer cell properties that contains tropomyosin 4--anaplastic lymphoma kinase gene fusion. |journal=Blood |volume=98 |issue= 4 |pages= 1209-16 |year= 2001 |pmid= 11493472 |doi=  }}
+*{{cite journal   |vauthors=Yi J, Kloeker S, Jensen CC, etal |title=Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers |journal=J. Biol. Chem. |volume=277 |issue= 11 |pages= 9580–9 |year= 2002 |pmid= 11782456 |doi= 10.1074/jbc.M106922200 }}
-*{{cite journal  | author=Yi J, Kloeker S, Jensen CC, ''et al.'' |title=Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers. |journal=J. Biol. Chem. |volume=277 |issue= 11 |pages= 9580-9 |year= 2002 |pmid= 11782456 |doi= 10.1074/jbc.M106922200 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Gevaert K, Goethals M, Martens L, etal |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810 }}
-*{{cite journal  | author=Gevaert K, Goethals M, Martens L, ''et al.'' |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566-9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810 }}
+*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal  | vauthors=Lin KT, Lu RM, Tarn WY |title=The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo |journal=Mol. Cell. Biol. |volume=24 |issue= 20 |pages= 9176–85 |year= 2004 |pmid= 15456888 |doi= 10.1128/MCB.24.20.9176-9185.2004  | pmc=517884 }}
-*{{cite journal  | author=Lin KT, Lu RM, Tarn WY |title=The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo. |journal=Mol. Cell. Biol. |volume=24 |issue= 20 |pages= 9176-85 |year= 2004 |pmid= 15456888 |doi= 10.1128/MCB.24.20.9176-9185.2004 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Bruneel A, Labas V, Mailloux A, etal |title=Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis |journal=Proteomics |volume=5 |issue= 15 |pages= 3876–84 |year= 2006 |pmid= 16130169 |doi= 10.1002/pmic.200401239 }}
-*{{cite journal  | author=Bruneel A, Labas V, Mailloux A, ''et al.'' |title=Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis. |journal=Proteomics |volume=5 |issue= 15 |pages= 3876-84 |year= 2006 |pmid= 16130169 |doi= 10.1002/pmic.200401239 }}
+*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
-*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
 }}
 {{refend}}
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+{{Cytoskeletal Proteins}}
+{{gene-19-stub}}

TPM4: Difference between revisions

Latest revision as of 05:21, 16 March 2018

References

Further reading

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