Peutz-Jeghers syndrome pathophysiology: Difference between revisions
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{{Peutz-Jeghers syndrome}} | {{Peutz-Jeghers syndrome}} | ||
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==Overview== | ==Overview== | ||
Revision as of 16:05, 18 August 2015
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Peutz-Jeghers syndrome Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Genetics
In 1998, a gene was found to be associated with the mutation. On chromosome 19, the gene known as STK11 (LKB1)[1] is a possible tumor suppressor gene. It is inherited in an Autosomal Dominant pattern (see Mendelian inheritance) which means that anyone who has PJS has a 50% chance of passing it onto their children.
References
- ↑ "UniProtKB/Swiss-Prot entry Q15831 [STK11_HUMAN] Serine/threonine-protein kinase 11". Retrieved 2007-07-21.
Template:Digestive system neoplasia
de:Peutz-Jeghers-Syndrom
it:Sindrome di Peutz-Jeghers
nl:Syndroom van Peutz-Jeghers