Chondrosarcoma natural history

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Overview

Complications that can develop as a result of chondrosarcoma are metastasis and recurrence. The prognosis of chondrosarcoma is good with treatment.

Complications

• Chondrosarcoma may cause metastasis to other organs.
• Lung is the most common location for metastatic disease.
• Chondrosarcoma may return and may need treatment with surgery, chemotherapy or radiation. Unlike other cancers, chondrosarcoma can return many years later.

Prognosis

• Generally, chondrosarcoma carries a good prognosis.
• Chondrosarcoma is associated with a 5 year survival rate of 75%.
• Depending upon the subtype, prognosis vary substantially:
  • Chondrosarcoma NOS: 70% 5 year survival.
  • Myxoid chondrosarcoma: 70% 5 year survival.
  • Mesenchymal chondrosarcoma: 50% 5 year survival.
  • Dedifferentiated chondrosarcoma: 10% 5 year survival.
• Prognosis varies with grade:
  • Grade 1: 90% 5 year survival.
  • Grade 3: 29% 5 year survival
• Prognosis varies with location:
  • long bones have a better prognosis than axial skeleton.

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