Peutz-Jeghers syndrome diagnostic study of choice: Difference between revisions
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==Overview== | ==Overview== | ||
Peutz-Jeghers syndrome is | The diagnosis of Peutz-Jeghers syndrome is made when at least 2 of the following 3 diagnostic criteria are met: positive [[family history]], mucocutaneous pigmentation, and presence of [[hamartomatous]] [[polyps]] | ||
==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
Peutz-Jeghers syndrome is | The diagnosis of Peutz-Jeghers syndrome is made when at least 2 of the following 3 diagnostic criteria are met: | ||
*[[ | *Positive [[family history]] | ||
*[[Mucocutaneous]] [[pigmentation]] causing patches of hyperpigmentation in the oral mucosa ([[gingiva]], [[hard palate]], [[buccal mucosa]], and labial mucosa) and on the hands and feet. The oral pigmentations are the first on the body to appear, and thus play an important part in early diagnosis | *[[Mucocutaneous]] [[pigmentation]] causing patches of hyperpigmentation in the oral mucosa ([[gingiva]], [[hard palate]], [[buccal mucosa]], and labial mucosa) and on the hands and feet. The oral pigmentations are the first on the body to appear, and thus play an important part in early diagnosis | ||
*[[ | *Presence of [[hamartomatous]] [[polyps]] in the [[gastrointestinal tract]] | ||
Revision as of 14:57, 18 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
The diagnosis of Peutz-Jeghers syndrome is made when at least 2 of the following 3 diagnostic criteria are met: positive family history, mucocutaneous pigmentation, and presence of hamartomatous polyps
Diagnostic Criteria
The diagnosis of Peutz-Jeghers syndrome is made when at least 2 of the following 3 diagnostic criteria are met:
- Positive family history
- Mucocutaneous pigmentation causing patches of hyperpigmentation in the oral mucosa (gingiva, hard palate, buccal mucosa, and labial mucosa) and on the hands and feet. The oral pigmentations are the first on the body to appear, and thus play an important part in early diagnosis
- Presence of hamartomatous polyps in the gastrointestinal tract