Transitional cell carcinoma differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Differential Diagnosis

Transitional cell carcinoma of bladder must be differentiated from:

• Squamous cell carcinoma of the bladder
• Adenocarcinoma of the bladder
• Renal cancer
• Renal stones
• Cystitis
• Glomerulonephritis
• Pyelonephritis
• Benign prostatic hyperplasia
• Prostate cancer
• Prostatitis

Transitional cell carcinoma of renal pelvis must be differentiated from: Filling defect within renal pelvis/dilated calyx

• Renal stone:

• Usually significantly higher attenuating
• Non-enhancing

• Blood clot:

• May be similar in attenuation (blood clot is usually a little higher)
• Does not enhance
• Changes configuration on short term follow up

• Pyelitis cystica
• Renal tuberculosis
• Papillary necrosis