Transitional cell carcinoma epidemiology and demographics: Difference between revisions
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There is a strong male predilection (M:F = | There is a strong male predilection (M:F = 2:1), at least in part due to many tumors (especially historically) having been due to industrial exposure. | ||
==References== | ==References== | ||
Revision as of 16:25, 18 February 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Epidemiology and Demographics
- Transitional cell carcinoma of the renal pelvis, accounts for only 7% of all kidney tumors.[1]
- Transitional cell cancer of the ureter, accounts for only 1 of every 25 upper tract tumors.
- They are curable in more than 90% of patients if they are superficial and confined to the renal pelvis or ureter.
- Patients with deeply invasive tumors that are still confined to the renal pelvis or ureter have a 10% to 15% likelihood of cure.
- Patients with tumors with penetration through the urothelial wall or with distant metastases usually cannot be cured with currently available forms of treatment.
Age
- Transitional cell carcinoma is typically a tumor of older patients, with the average age of presentation being 65, and the majority of patients being over the age of 60.
- Transitional cell carcinoma of the urinary bladder is rare in young adults, as less than 1% of such tumors present in the first 4 decades of life.[2]
Gender
There is a strong male predilection (M:F = 2:1), at least in part due to many tumors (especially historically) having been due to industrial exposure.
References
- ↑ Transitional cell cancer. National cancer institute. http://www.cancer.gov/types/kidney/hp/transitional-cell-treatment-pdq#section/_1
- ↑ Nomikos, Michael; Pappas, Athanasios; Kopaka, Maria-Emmanouela; Tzoulakis, Stavros; Volonakis, Ioannis; Stavrakakis, Georgios; Avgenakis, Georgios; Anezinis, Ploutarchos (2011). "Urothelial Carcinoma of the Urinary Bladder in Young Adults: Presentation, Clinical behavior and Outcome". Advances in Urology. 2011: 1–4. doi:10.1155/2011/480738. ISSN 1687-6369.