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'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
{{Syndrome of inappropriate antidiuretic hormone}}
{{Syndrome of inappropriate antidiuretic hormone}}
{{CMG}}
{{CMG}}; {{Vbe}}


'''''Synonyms and Keywords:''''' SIADH; syndrome of inappropriate antidiuretic hormone secretion; inappropriate ADH syndrome; Schwartz-Bartter syndrome.
'''''Synonyms and Keywords:''''' SIADH; syndrome of inappropriate antidiuretic hormone secretion; inappropriate ADH syndrome; Schwartz-Bartter syndrome.
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==[[Syndrome of inappropriate antidiuretic hormone differential diagnosis|Differentiating Syndrome of inappropriate antidiuretic hormone from other Diseases]]==
==[[Syndrome of inappropriate antidiuretic hormone differential diagnosis|Differentiating Syndrome of inappropriate antidiuretic hormone from other Diseases]]==


Syndrome of inappropriate antidiuretic hormone secretion (SIADH) was initially described by Leaf and Mamby. [1] SIADH consists of hyponatremia, inappropriately elevated urine osmolality, excessive urine sodium and decreased serum osmolality in a euvolemic patient without edema. These findings should occur in the absence of diuretic treatment with normal cardiac, renal, adrenal, hepatic and thyroid function. Hyponatremia occurs in about 30% of hospitalized patients [2] and SIADH is the most frequent cause of hyponatremia


==[[Syndrome of inappropriate antidiuretic hormone epidemiology and demographics|Epidemiology and Demographics]]==
==[[Syndrome of inappropriate antidiuretic hormone epidemiology and demographics|Epidemiology and Demographics]]==

Revision as of 15:59, 1 August 2017

Syndrome of inappropriate antidiuretic hormone
ICD-10 E22.2
ICD-9 253.6
DiseasesDB 12050
MedlinePlus 003702
MeSH D007177

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Vindhya BellamKonda, M.B.B.S [2]

Synonyms and Keywords: SIADH; syndrome of inappropriate antidiuretic hormone secretion; inappropriate ADH syndrome; Schwartz-Bartter syndrome.

Overview

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) was initially described by Leaf and Mamby. SIADH consists of hyponatremia, inappropriately elevated urine osmolality, excessive urine sodium and decreased serum osmolality in a euvolemic patient without edema. These findings should occur in the absence of diuretic treatment with normal cardiac, renal, adrenal, hepatic and thyroid function. Hyponatremia occurs in about 30% of hospitalized patients and SIADH is the most frequent cause of hyponatremia. Differentiating hyponatremia due to SIADH from other causes of hyponatremia becomes essential to evaluate the treatment plan.

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Syndrome of inappropriate antidiuretic hormone from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

it:Sindrome da inappropriata secrezione di ADH nl:Syndroom van inadequate secretie van antidiuretisch hormoon


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