Syndrome of inappropriate antidiuretic hormone causes: Difference between revisions

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Revision as of 18:00, 14 August 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]

Overview

SIADH is caused by excess of renal water reabsorption through inappropriate antidiuretic hormone secretion, there are various causes attributed to SIADH ranging from malignancies, drugs, central nervous system causes, infectious.Some of the most common causes are : malignancies like small cell lung cancer, drugs like selective serotonin reuptake inhibitors, and carbamazapine

Syndrome of inappropriate antidiuretic hormone causes

Common causes

Head injury

Subarachnoid hemorrhage
Cancers
- Lung cancer (especially small cell lung cancer, as well as other small-cell malignancies of other organs)
Infections
Drugs
- Chlorpropamide
- Cyclophosphamide
- Carbamazepine
- Selective serotonin reuptake inhibitors
- Methylenedioxymethamphetamine (MDMA, commonly called Ecstasy)

Causes by Organ System

Cardiovascular	No underlying causes
Chemical / poisoning	Mesothelioma
Cardiovascular	No underlying causes
Chemical / poisoning	Mesothelioma
Dermatologic	No underlying causes
Drug Side Effect	Carbamazepine, Chlorpropamide, Cyclophosphamide, Desmopressin, Mono Amine Oxidase Inhibitors, Nicotine, Oxytocin, Pergolide, Phenothiazines, SSRIs, Tricyclic antidepressants, Tolbutamide, Vasopressin, Vinblastine, Vincristine, Bromocriptine,Clofibrate,Prostaglandins,Melphalan,Interferon-alpha,Tacrolimus, Diclofenac, Ibuprofen, Fentanyl, Amiodarone, Hydrochlorthiazide, Clonidine,Levodopa,Rituximab, Methylene dioxy methamphetamine, Leveteiracetam, Quinolones.
Ear Nose Throat	No underlying causes
Endocrine	Carcinoid,Hypopituitarism,Hypothyroidism
Environmental	Mesothelioma
Gastroenterologic	Carcinoid, Duodenal carcinoma, Pancreatic cancer
Genetic	Agenesis corpus collosum, Amyotropic lateral sclerosis, Hydrocephalus, Midline defects, Multiple sclerosis
Hematologic	Thymoma, Acute intermittent porphyria
Iatrogenic	No underlying causes
Infectious Disease	AIDS, Bacterial pneumonia, Brain abscess, Encephalitis, Lung abscess, Lung cavitation, Meningitis, Tuberculosis
Musculoskeletal / Ortho	Amyotropic lateral sclerosis, Ewing's sarcoma, Polyradiculitis
Neurologic	Agenesis corpus collosum, Amyotropic lateral sclerosis, Brain abscess, Carcinoid, Cavernous sinus thrombosis, Delirium tremens, Encephalitis, Hydrocephalus, Meningitis, Multiple sclerosis, Peripheral neuropathy, Polyradiculitis, Stroke,Subarachnoid hemorrhage, Subdural hemorrhage,Guillian barre syndrome, Traumatic brain injury
Nutritional / Metabolic	No underlying causes
Obstetric/Gynecologic	Ovarian cancer
Oncologic	Bronchial adenoma, Carcinoid, Duodenal carcinoma, Ewing's sarcoma, Lung carcinoma, Mesothelioma, Ovarian cancer, Pancreatic cancer, Thymoma
Opthalmologic	No underlying causes
Overdose / Toxicity	Delirium tremens
Psychiatric	Phenothiazines, Psychosis
Pulmonary	Asthma, Bacterial pneumonia, Bronchial adenoma, Carcinoid, Lung abscess, Lung carcinoma, Lung cavitation, Mesothelioma, Pneumothorax, Tuberculosis
Renal / Electrolyte	No underlying causes
Rheum / Immune / Allergy	Asthma
Sexual	No underlying causes
Trauma	Pneumothorax
Urologic	No underlying causes
Miscellaneous	Positive pressure ventilation, transsphenoidal surgery , Poly-arteritis nodosa

Causes in Alphabetical Order

References

Template:WikiDoc Sources

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-| bgcolor="Beige" | [[AIDS]], Bacterial [[pneumonia]], [[Brain abscess]], [[Encephalitis]], [[Lung abscess]], Lung cavitation, [[Meningitis]], [[Tuberculosis]]
+| bgcolor="Beige" | [[AIDS]], Bacterial [[pneumonia]], [[Brain abscess]], [[Encephalitis]], [[Lung abscess]], [[Lung cavitation]], [[Meningitis]], [[Tuberculosis]]
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