Syndrome of inappropriate antidiuretic hormone epidemiology and demographics: Difference between revisions
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==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
=== Incidence === | |||
* SIADH is the most common cause of [[hyponatremia]].<ref name="pmid19881931">{{cite journal |vauthors=O'Donoghue D, Trehan A |title=SIADH and hyponatraemia: foreword |journal=NDT Plus |volume=2 |issue=Suppl_3 |pages=iii1–iii4 |year=2009 |pmid=19881931 |pmc=2762825 |doi=10.1093/ndtplus/sfp152 |url=}}</ref> | |||
* [[Incidence]] of moderate and severe [[hyponatraemia]] in the United States ranges from a low of 1000 to 7000 per 100,000 among hospitalized patients.<ref name="pmid198819312">{{cite journal |vauthors=O'Donoghue D, Trehan A |title=SIADH and hyponatraemia: foreword |journal=NDT Plus |volume=2 |issue=Suppl_3 |pages=iii1–iii4 |year=2009 |pmid=19881931 |pmc=2762825 |doi=10.1093/ndtplus/sfp152 |url=}}</ref> | |||
===Prevalence=== | ===Prevalence=== | ||
*[[Prevalence]] of [[SIADH]] was estimated to be 2500-3000 cases per 100,000 individuals. | *[[Prevalence]] of [[SIADH]] was estimated to be 2500-3000 cases per 100,000 individuals. | ||
*Prevalence of [[hyponatremia]] in the United States has been estimated to be 1720 per 100,000 individuals.<ref name="pmid24262726">{{cite journal |vauthors=Mohan S, Gu S, Parikh A, Radhakrishnan J |title=Prevalence of hyponatremia and association with mortality: results from NHANES |journal=Am. J. Med. |volume=126 |issue=12 |pages=1127–37.e1 |year=2013 |pmid=24262726 |pmc=3933395 |doi=10.1016/j.amjmed.2013.07.021 |url=}}</ref> | *Prevalence of [[hyponatremia]] in the United States has been estimated to be 1720 per 100,000 individuals.<ref name="pmid24262726">{{cite journal |vauthors=Mohan S, Gu S, Parikh A, Radhakrishnan J |title=Prevalence of hyponatremia and association with mortality: results from NHANES |journal=Am. J. Med. |volume=126 |issue=12 |pages=1127–37.e1 |year=2013 |pmid=24262726 |pmc=3933395 |doi=10.1016/j.amjmed.2013.07.021 |url=}}</ref> | ||
=== | === Mortality === | ||
* | * Hospitalized patients with plasma [[sodium]] concentration <125 mmol/l show an overall mortality of 28000 per 100,000 patients.<ref name="GillHuda2006">{{cite journal|last1=Gill|first1=Geoffrey|last2=Huda|first2=Bobby|last3=Boyd|first3=Alice|last4=Skagen|first4=Karolina|last5=Wile|first5=David|last6=Watson|first6=Ian|last7=van Heyningen|first7=Charles|title=Characteristics and mortality of severe hyponatraemia ? a hospital-based study|journal=Clinical Endocrinology|volume=65|issue=2|year=2006|pages=246–249|issn=0300-0664|doi=10.1111/j.1365-2265.2006.02583.x}}</ref> | ||
===Age=== | ===Age=== | ||
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===Race=== | ===Race=== | ||
*There is no racial predilection to [[SIADH]]. | *There is no racial predilection to [[SIADH]]. | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Medicine]] | |||
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[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
[[Category:Nephrology]] | |||
[[Category:Neurology]] | [[Category:Neurology]] | ||
[[Category: | [[Category:Up-To-Date]] | ||
[[Category:Primary care]] | |||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]
Overview
Syndrome of inappropriate antidiuretic hormone (SIADH) can occur at any age. Its incidence depends upon various possible etiologies. Prevalence of SIADH was estimated to be 2500-3000 cases per 100,000 individuals. The incidence and prevalence of SIADH in particular is less thoroughly studied in the literature.
Epidemiology and Demographics
Incidence
- SIADH is the most common cause of hyponatremia.[1]
- Incidence of moderate and severe hyponatraemia in the United States ranges from a low of 1000 to 7000 per 100,000 among hospitalized patients.[2]
Prevalence
- Prevalence of SIADH was estimated to be 2500-3000 cases per 100,000 individuals.
- Prevalence of hyponatremia in the United States has been estimated to be 1720 per 100,000 individuals.[3]
Mortality
- Hospitalized patients with plasma sodium concentration <125 mmol/l show an overall mortality of 28000 per 100,000 patients.[4]
Age
Gender
- The prevalence and incidence of SIADH does not vary by gender.
- The prevalence of hyponatremia is higher in females than males.[7]
Race
- There is no racial predilection to SIADH.
References
- ↑ O'Donoghue D, Trehan A (2009). "SIADH and hyponatraemia: foreword". NDT Plus. 2 (Suppl_3): iii1–iii4. doi:10.1093/ndtplus/sfp152. PMC 2762825. PMID 19881931.
- ↑ O'Donoghue D, Trehan A (2009). "SIADH and hyponatraemia: foreword". NDT Plus. 2 (Suppl_3): iii1–iii4. doi:10.1093/ndtplus/sfp152. PMC 2762825. PMID 19881931.
- ↑ Mohan S, Gu S, Parikh A, Radhakrishnan J (2013). "Prevalence of hyponatremia and association with mortality: results from NHANES". Am. J. Med. 126 (12): 1127–37.e1. doi:10.1016/j.amjmed.2013.07.021. PMC 3933395. PMID 24262726.
- ↑ Gill, Geoffrey; Huda, Bobby; Boyd, Alice; Skagen, Karolina; Wile, David; Watson, Ian; van Heyningen, Charles (2006). "Characteristics and mortality of severe hyponatraemia ? a hospital-based study". Clinical Endocrinology. 65 (2): 246–249. doi:10.1111/j.1365-2265.2006.02583.x. ISSN 0300-0664.
- ↑ Tarif N, Sabir O, Niaz A, Akhtar R, Rafique K, Rizvi N (2016). "Hyponatraemia: Epidemiology and aetiology in a tertiary care centre in Pakistan". J Pak Med Assoc. 66 (11): 1436–1439. PMID 27812063.
- ↑ Flear CT, Gill GV, Burn J (1981). "Hyponatraemia: mechanisms and management". Lancet. 2 (8236): 26–31. PMID 6113402.
- ↑ Lien YH, Shapiro JI (2007). "Hyponatremia: clinical diagnosis and management". Am. J. Med. 120 (8): 653–8. doi:10.1016/j.amjmed.2006.09.031. PMID 17679119.