Peutz-Jeghers syndrome physical examination: Difference between revisions
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==Physical Examination== | ==Physical Examination== | ||
The physical exam findings are as follows:<ref name="KopacovaTacheci2009">{{cite journal|last1=Kopacova|first1=Marcela|last2=Tacheci|first2=Ilja|last3=Rejchrt|first3=Stanislav|last4=Bures|first4=Jan|title=Peutz-Jeghers syndrome: Diagnostic and therapeuticapproach|journal=World Journal of Gastroenterology|volume=15|issue=43|year=2009|pages=5397|issn=1007-9327|doi=10.3748/wjg.15.5397}}</ref><ref name="KopacovaTacheci2009">{{cite journal|last1=Kopacova|first1=Marcela|last2=Tacheci|first2=Ilja|last3=Rejchrt|first3=Stanislav|last4=Bures|first4=Jan|title=Peutz-Jeghers syndrome: Diagnostic and therapeuticapproach|journal=World Journal of Gastroenterology|volume=15|issue=43|year=2009|pages=5397|issn=1007-9327|doi=10.3748/wjg.15.5397}}</ref><ref name="pmid25460448">{{cite journal| author=Hofmann S, Barth TF, Kornmann M, Henne-Bruns D| title=Appendix carcinoid associated with the Peutz-Jeghers syndrome. | journal=Int J Surg Case Rep | year= 2014 | volume= 5 | issue= 12 | pages= 964-7 | pmid=25460448 | doi=10.1016/j.ijscr.2014.06.024 | pmc=PMC4276270 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25460448 }} </ref><ref name="pmid25460448">{{cite journal| author=Hofmann S, Barth TF, Kornmann M, Henne-Bruns D| title=Appendix carcinoid associated with the Peutz-Jeghers syndrome. | journal=Int J Surg Case Rep | year= 2014 | volume= 5 | issue= 12 | pages= 964-7 | pmid=25460448 | doi=10.1016/j.ijscr.2014.06.024 | pmc=PMC4276270 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25460448 }} </ref> | |||
===Appearance of the Patient=== | ===Appearance of the Patient=== | ||
*[[Cachexia]] may be suggestive of [[cancer]]. | *[[Cachexia]] may be suggestive of [[cancer]]. | ||
===Vitals=== | ===Vitals=== | ||
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===Skin=== | ===Skin=== | ||
*Patches of [[hyperpigmentation]] on the hands and feet | *Patches of [[hyperpigmentation]] on the hands and feet | ||
*[[Jaundice]] may be suggestive of [[pancreatic cancer]] | *[[Jaundice]] may be suggestive of [[pancreatic cancer]] | ||
| Line 24: | Line 25: | ||
===Throat=== | ===Throat=== | ||
*Oral mucosa | *Oral mucosa | ||
:*[[Mucocutaneous]] [[pigmentation]] causing patches of hyperpigmentation in the oral mucosa ([[gingiva]], [[hard palate]], [[buccal mucosa]], and labial mucosa) | :*[[Mucocutaneous]] [[pigmentation]] causing patches of hyperpigmentation in the oral mucosa ([[gingiva]], [[hard palate]], [[buccal mucosa]], and labial mucosa) | ||
===Neck=== | ===Neck=== | ||
| Line 47: | Line 48: | ||
===Extremities=== | ===Extremities=== | ||
*Patches of [[hyperpigmentation]] on the hands and feet | *Patches of [[hyperpigmentation]] on the hands and feet | ||
*[[Clubbing]] may be suggestive of lung cancer | *[[Clubbing]] may be suggestive of lung cancer | ||
*[[Cyanosis]] may be suggestive of lung cancer | *[[Cyanosis]] may be suggestive of lung cancer | ||
Revision as of 17:12, 20 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]
Overview
Common physical examination findings of Peutz-Jeghers syndrome include mucocutaneous hyperpigmentation, abdominal tenderness due to intussusception, bowel obstruction, and pallor due to anemia.
Physical Examination
The physical exam findings are as follows:[1][1][2][2]
Appearance of the Patient
Vitals
Skin
- Patches of hyperpigmentation on the hands and feet
- Jaundice may be suggestive of pancreatic cancer
Eyes
- Icteric sclera
Throat
- Oral mucosa
- Mucocutaneous pigmentation causing patches of hyperpigmentation in the oral mucosa (gingiva, hard palate, buccal mucosa, and labial mucosa)
Neck
Lungs
- If lung cancer develops, the patient may present with the following:
- Wheezing
- Consolidation with reduced breath sounds on auscultation
- Rales
- Egophony
- Chest movement may be asymmetric
Abdomen
- Abdominal distention
- Abdominal tenderness
- Rebound tenderness
- An acute abdomen may be suggestive of intussusception
- An abdominal mass may be suggestive of hepatic or pancreatic cancer
- Guarding
- Hepatomegaly may be suggestive of hepatic cancer
Extremities
- Patches of hyperpigmentation on the hands and feet
- Clubbing may be suggestive of lung cancer
- Cyanosis may be suggestive of lung cancer
References
- ↑ 1.0 1.1 Kopacova, Marcela; Tacheci, Ilja; Rejchrt, Stanislav; Bures, Jan (2009). "Peutz-Jeghers syndrome: Diagnostic and therapeuticapproach". World Journal of Gastroenterology. 15 (43): 5397. doi:10.3748/wjg.15.5397. ISSN 1007-9327.
- ↑ 2.0 2.1 Hofmann S, Barth TF, Kornmann M, Henne-Bruns D (2014). "Appendix carcinoid associated with the Peutz-Jeghers syndrome". Int J Surg Case Rep. 5 (12): 964–7. doi:10.1016/j.ijscr.2014.06.024. PMC 4276270. PMID 25460448.