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==Overview==
==Overview==
Biopsy for lung mass may be classified into 2 categories: non-surgical biopsy and surgical biopsy. Biopsy findings associated with lung mass will depend on tumor [[histology]]. Common types of lung tissue biopsy for pulmonary mass, include: conventional bronchoscopic-guided transbronchial biopsy, bronchoscopic-transbronchial needle aspiration, endobronchial ultrasound-guided sheath transbronchial biopsy, and endobronchial ultrasound-guided transbronchial needle aspiration. Common indications for biopsy in lung mass, include: suspected lung cancer, malignant features (lymph node involvement).<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>


==Other Imaging Findings==
==Other Diagnostic Studies==
===Biopsy===
Biopsy for lung mass may be classified into 2 categories:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
:*Bronchoscopy
:*Transthoracic needle biopsy
:*Needle core biopsy
*'''Surgical'''
:* Wedge resection
* The preferred biopsy technique for lung mass is wedge resection.
 
*Indications for biopsy in lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
:*Suspected lung cancer
:*Determination of tumor histologic subtype
:*Characterization of genetic mutations
 
*Contraindications for biopsy in lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
:*Emphysema
:*Bullous disease
:*Chronic respiratory failure
 
*Complications for for biopsy in lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
:*Pneumothorax
:*Hemothorax
==Non-Surgical Biopsy==
 
'''Bronchoscopy'''
 
*Common bronchoscopy biopsy techniques for lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
:*Conventional bronchoscopic-guided transbronchial biopsy
:*Bronchoscopic-transbronchial needle aspiration
:*Endobronchial ultrasound-guided sheath transbronchial biopsy
:*Endobronchial ultrasound-guided transbronchial needle aspiration
 
*Indications for bronchoscopy in lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
:*Central nodules
:*Large lesions
:*No fitness for surgery
:*Nodules close to the patent airways
:*Patients were the risk of complications from any other biopsy is high
 
'''Transthoracic needle biopsy'''
*Usually followed by CT guidance
*Indications for transthoracic needle biopsy in pulmonary nodule, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
:*Peripheral nodules
:*Nodules close to the chest wall
:*No fitness for surgery
 
==Surgical Biopsy==
*Surgical excision is the mainstay therapy for malignant lung mass
*Surgical excision is also the primary choice for the definitive diagnosis of malignant lung mass
*In lung mass, surgical procedure selection will depend on the size, margins, and size of the tumor.
*Common surgical procedures for the treatment of lung mass, include:
:*Wedge resection
:*Lobectomy
:*Segmentectomy
:*Lung volume reduction surgery


==References==
==References==

Revision as of 18:52, 23 February 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief:

Overview

Biopsy for lung mass may be classified into 2 categories: non-surgical biopsy and surgical biopsy. Biopsy findings associated with lung mass will depend on tumor histology. Common types of lung tissue biopsy for pulmonary mass, include: conventional bronchoscopic-guided transbronchial biopsy, bronchoscopic-transbronchial needle aspiration, endobronchial ultrasound-guided sheath transbronchial biopsy, and endobronchial ultrasound-guided transbronchial needle aspiration. Common indications for biopsy in lung mass, include: suspected lung cancer, malignant features (lymph node involvement).[1]

Other Diagnostic Studies

Biopsy

Biopsy for lung mass may be classified into 2 categories:[1]

  • Bronchoscopy
  • Transthoracic needle biopsy
  • Needle core biopsy
  • Surgical
  • Wedge resection
  • The preferred biopsy technique for lung mass is wedge resection.
  • Indications for biopsy in lung mass, include:[1]
  • Suspected lung cancer
  • Determination of tumor histologic subtype
  • Characterization of genetic mutations
  • Contraindications for biopsy in lung mass, include:[1]
  • Emphysema
  • Bullous disease
  • Chronic respiratory failure
  • Complications for for biopsy in lung mass, include:[1]
  • Pneumothorax
  • Hemothorax

Non-Surgical Biopsy

Bronchoscopy

  • Common bronchoscopy biopsy techniques for lung mass, include:[1]
  • Conventional bronchoscopic-guided transbronchial biopsy
  • Bronchoscopic-transbronchial needle aspiration
  • Endobronchial ultrasound-guided sheath transbronchial biopsy
  • Endobronchial ultrasound-guided transbronchial needle aspiration
  • Indications for bronchoscopy in lung mass, include:[1]
  • Central nodules
  • Large lesions
  • No fitness for surgery
  • Nodules close to the patent airways
  • Patients were the risk of complications from any other biopsy is high

Transthoracic needle biopsy

  • Usually followed by CT guidance
  • Indications for transthoracic needle biopsy in pulmonary nodule, include:[1]
  • Peripheral nodules
  • Nodules close to the chest wall
  • No fitness for surgery

Surgical Biopsy

  • Surgical excision is the mainstay therapy for malignant lung mass
  • Surgical excision is also the primary choice for the definitive diagnosis of malignant lung mass
  • In lung mass, surgical procedure selection will depend on the size, margins, and size of the tumor.
  • Common surgical procedures for the treatment of lung mass, include:
  • Wedge resection
  • Lobectomy
  • Segmentectomy
  • Lung volume reduction surgery

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM (2004). "Percutaneous biopsy in evaluation of lung nodules". JSLS. 8 (3): 213–6. PMC 3016799. PMID 15347106.
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