GNA11: Difference between revisions
Jump to navigation
Jump to search
m Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}) |
m Bot: HTTP→HTTPS |
||
Line 1: | Line 1: | ||
{{Infobox_gene}} | |||
{{ | '''Guanine nucleotide-binding protein subunit alpha-11''' is a [[protein]] that in humans is encoded by the ''GNA11'' [[gene]].<ref name="pmid1302014">{{cite journal |vauthors=Wilkie TM, Gilbert DJ, Olsen AS, Chen XN, Amatruda TT, Korenberg JR, Trask BJ, de Jong P, Reed RR, Simon MI | title = Evolution of the mammalian G protein alpha subunit multigene family | journal = Nat Genet | volume = 1 | issue = 2 | pages = 85–91 |date=Jun 1993 | pmid = 1302014 | pmc = | doi = 10.1038/ng0592-85 |display-authors=etal}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2767| accessdate = }}</ref> Together with [[GNAQ]] (its [[paralogue]]), it functions as a [[Gq alpha subunit]].<ref>[http://www.omim.org/entry/139313 139313 GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-11; GNA11] at [[OMIM]]. Retrieved January 1, 2015.</ref> | ||
}} | |||
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. --> | <!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. --> | ||
Line 62: | Line 12: | ||
==References== | ==References== | ||
{{reflist | {{reflist}} | ||
==Further reading== | ==Further reading== | ||
{{refbegin | 2}} | {{refbegin | 2}} | ||
{{PBB_Further_reading | {{PBB_Further_reading | ||
| citations = | | citations = | ||
*{{cite journal | | *{{cite journal |vauthors=Raymond JR, Mukhin YV, Gelasco A |title=Multiplicity of mechanisms of serotonin receptor signal transduction. |journal=Pharmacol. Ther. |volume=92 |issue= 2–3 |pages= 179–212 |year= 2002 |pmid= 11916537 |doi=10.1016/S0163-7258(01)00169-3 |display-authors=etal}} | ||
*{{cite journal |vauthors=Jiang M, Pandey S, Tran VT, Fong HK |title=Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 9 |pages= 3907–11 |year= 1991 |pmid= 1902575 |doi=10.1073/pnas.88.9.3907 | pmc=51562 }} | |||
*{{cite journal | | *{{cite journal |vauthors=Thomas CP, Dunn MJ, Mattera R |title=Ca2+ signalling in K562 human erythroleukaemia cells: effect of dimethyl sulphoxide and role of G-proteins in thrombin- and thromboxane A2-activated pathways |journal=Biochem. J. |volume=312 |issue= 1|pages= 151–8 |year= 1996 |pmid= 7492305 |doi= | pmc=1136238 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Offermanns S, Simon MI |title=G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C |journal=J. Biol. Chem. |volume=270 |issue= 25 |pages= 15175–80 |year= 1995 |pmid= 7797501 |doi=10.1074/jbc.270.25.15175 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Stanners J, Kabouridis PS, McGuire KL, Tsoukas CD |title=Interaction between G proteins and tyrosine kinases upon T cell receptor.CD3-mediated signaling |journal=J. Biol. Chem. |volume=270 |issue= 51 |pages= 30635–42 |year= 1996 |pmid= 8530500 |doi=10.1074/jbc.270.51.30635 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Laugwitz KL, Allgeier A, Offermanns S |title=The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 1 |pages= 116–20 |year= 1996 |pmid= 8552586 |doi=10.1073/pnas.93.1.116 | pmc=40189 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal |vauthors=Launay JM, Birraux G, Bondoux D |title=Ras involvement in signal transduction by the serotonin 5-HT2B receptor |journal=J. Biol. Chem. |volume=271 |issue= 6 |pages= 3141–7 |year= 1996 |pmid= 8621713 |doi=10.1074/jbc.271.6.3141 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal |vauthors=Johnson GJ, Leis LA, Dunlop PC |title=Specificity of G alpha q and G alpha 11 gene expression in platelets and erythrocytes. Expressions of cellular differentiation and species differences |journal=Biochem. J. |volume=318 |issue= 3|pages= 1023–31 |year= 1996 |pmid= 8836152 |doi= | pmc=1217719 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Kinsella BT, O'Mahony DJ, Fitzgerald GA |title=The human thromboxane A2 receptor alpha isoform (TP alpha) functionally couples to the G proteins Gq and G11 in vivo and is activated by the isoprostane 8-epi prostaglandin F2 alpha |journal=J. Pharmacol. Exp. Ther. |volume=281 |issue= 2 |pages= 957–64 |year= 1997 |pmid= 9152406 |doi= }} | ||
*{{cite journal | | *{{cite journal |vauthors=Wise A, Parenti M, Milligan G |title=Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association |journal=FEBS Lett. |volume=407 |issue= 3 |pages= 257–60 |year= 1997 |pmid= 9175863 |doi=10.1016/S0014-5793(97)00300-1 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Carrasco MP, Asbóth G, Phaneuf S, López Bernal A |title=Activation of the prostaglandin FP receptor in human granulosa cells |journal=J. Reprod. Fertil. |volume=111 |issue= 2 |pages= 309–17 |year= 1998 |pmid= 9462300 |doi= 10.1530/jrf.0.1110309}} | ||
*{{cite journal | | *{{cite journal |vauthors=Qian A, Wang W, Sanborn BM |title=Evidence for the involvement of several intracellular domains in the coupling of oxytocin receptor to G alpha(q/11) |journal=Cell. Signal. |volume=10 |issue= 2 |pages= 101–5 |year= 1998 |pmid= 9481484 |doi=10.1016/S0898-6568(97)00097-1 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Dulin NO, Sorokin A, Reed E |title=RGS3 inhibits G protein-mediated signaling via translocation to the membrane and binding to Galpha11 |journal=Mol. Cell. Biol. |volume=19 |issue= 1 |pages= 714–23 |year= 1999 |pmid= 9858594 |doi= | pmc=83928 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal |vauthors=Hayes JS, Lawler OA, Walsh MT, Kinsella BT |title=The prostacyclin receptor is isoprenylated. Isoprenylation is required for efficient receptor-effector coupling |journal=J. Biol. Chem. |volume=274 |issue= 34 |pages= 23707–18 |year= 1999 |pmid= 10446129 |doi=10.1074/jbc.274.34.23707 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Brydon L, Roka F, Petit L |title=Dual signaling of human Mel1a melatonin receptors via G(i2), G(i3), and G(q/11) proteins |journal=Mol. Endocrinol. |volume=13 |issue= 12 |pages= 2025–38 |year= 2000 |pmid= 10598579 |doi=10.1210/me.13.12.2025 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal |vauthors=Corbetta S, Mantovani G, Lania A |title=Calcium-sensing receptor expression and signalling in human parathyroid adenomas and primary hyperplasia |journal=Clin. Endocrinol. |volume=52 |issue= 3 |pages= 339–48 |year= 2000 |pmid= 10718832 |doi=10.1046/j.1365-2265.2000.00933.x |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal |vauthors=Shraga-Levine Z, Sokolovsky M |title=Functional coupling of G proteins to endothelin receptors is ligand and receptor subtype specific |journal=Cell. Mol. Neurobiol. |volume=20 |issue= 3 |pages= 305–17 |year= 2000 |pmid= 10789830 |doi=10.1023/A:1007010125316 }} | ||
*{{cite journal | | *{{cite journal |vauthors=AbdAlla S, Lother H, Abdel-tawab AM, Quitterer U |title=The angiotensin II AT2 receptor is an AT1 receptor antagonist |journal=J. Biol. Chem. |volume=276 |issue= 43 |pages= 39721–6 |year= 2001 |pmid= 11507095 |doi= 10.1074/jbc.M105253200 }} | ||
*{{cite journal | | |||
}} | }} | ||
{{refend}} | {{refend}} | ||
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. --> | |||
{{PBB_Controls | |||
| update_page = yes | |||
| require_manual_inspection = no | |||
| update_protein_box = yes | |||
| update_summary = yes | |||
| update_citations = yes | |||
}} | |||
{{Intracellular signaling peptides and proteins}} | |||
{{GTPases}} | |||
{{gene-19-stub}} | {{gene-19-stub}} | ||
Revision as of 08:50, 31 August 2017
VALUE_ERROR (nil) | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Aliases | |||||||
External IDs | GeneCards: [1] | ||||||
Orthologs | |||||||
Species | Human | Mouse | |||||
Entrez |
|
| |||||
Ensembl |
|
| |||||
UniProt |
|
| |||||
RefSeq (mRNA) |
|
| |||||
RefSeq (protein) |
|
| |||||
Location (UCSC) | n/a | n/a | |||||
PubMed search | n/a | n/a | |||||
Wikidata | |||||||
|
Guanine nucleotide-binding protein subunit alpha-11 is a protein that in humans is encoded by the GNA11 gene.[1][2] Together with GNAQ (its paralogue), it functions as a Gq alpha subunit.[3]
See also
References
- ↑ Wilkie TM, Gilbert DJ, Olsen AS, Chen XN, Amatruda TT, Korenberg JR, Trask BJ, de Jong P, Reed RR, Simon MI, et al. (Jun 1993). "Evolution of the mammalian G protein alpha subunit multigene family". Nat Genet. 1 (2): 85–91. doi:10.1038/ng0592-85. PMID 1302014.
- ↑ "Entrez Gene: GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)".
- ↑ 139313 GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-11; GNA11 at OMIM. Retrieved January 1, 2015.
Further reading
- Raymond JR, Mukhin YV, Gelasco A, et al. (2002). "Multiplicity of mechanisms of serotonin receptor signal transduction". Pharmacol. Ther. 92 (2–3): 179–212. doi:10.1016/S0163-7258(01)00169-3. PMID 11916537.
- Jiang M, Pandey S, Tran VT, Fong HK (1991). "Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells". Proc. Natl. Acad. Sci. U.S.A. 88 (9): 3907–11. doi:10.1073/pnas.88.9.3907. PMC 51562. PMID 1902575.
- Thomas CP, Dunn MJ, Mattera R (1996). "Ca2+ signalling in K562 human erythroleukaemia cells: effect of dimethyl sulphoxide and role of G-proteins in thrombin- and thromboxane A2-activated pathways". Biochem. J. 312 (1): 151–8. PMC 1136238. PMID 7492305.
- Offermanns S, Simon MI (1995). "G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C". J. Biol. Chem. 270 (25): 15175–80. doi:10.1074/jbc.270.25.15175. PMID 7797501.
- Stanners J, Kabouridis PS, McGuire KL, Tsoukas CD (1996). "Interaction between G proteins and tyrosine kinases upon T cell receptor.CD3-mediated signaling". J. Biol. Chem. 270 (51): 30635–42. doi:10.1074/jbc.270.51.30635. PMID 8530500.
- Laugwitz KL, Allgeier A, Offermanns S, et al. (1996). "The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families". Proc. Natl. Acad. Sci. U.S.A. 93 (1): 116–20. doi:10.1073/pnas.93.1.116. PMC 40189. PMID 8552586.
- Launay JM, Birraux G, Bondoux D, et al. (1996). "Ras involvement in signal transduction by the serotonin 5-HT2B receptor". J. Biol. Chem. 271 (6): 3141–7. doi:10.1074/jbc.271.6.3141. PMID 8621713.
- Johnson GJ, Leis LA, Dunlop PC (1996). "Specificity of G alpha q and G alpha 11 gene expression in platelets and erythrocytes. Expressions of cellular differentiation and species differences". Biochem. J. 318 (3): 1023–31. PMC 1217719. PMID 8836152.
- Kinsella BT, O'Mahony DJ, Fitzgerald GA (1997). "The human thromboxane A2 receptor alpha isoform (TP alpha) functionally couples to the G proteins Gq and G11 in vivo and is activated by the isoprostane 8-epi prostaglandin F2 alpha". J. Pharmacol. Exp. Ther. 281 (2): 957–64. PMID 9152406.
- Wise A, Parenti M, Milligan G (1997). "Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association". FEBS Lett. 407 (3): 257–60. doi:10.1016/S0014-5793(97)00300-1. PMID 9175863.
- Carrasco MP, Asbóth G, Phaneuf S, López Bernal A (1998). "Activation of the prostaglandin FP receptor in human granulosa cells". J. Reprod. Fertil. 111 (2): 309–17. doi:10.1530/jrf.0.1110309. PMID 9462300.
- Qian A, Wang W, Sanborn BM (1998). "Evidence for the involvement of several intracellular domains in the coupling of oxytocin receptor to G alpha(q/11)". Cell. Signal. 10 (2): 101–5. doi:10.1016/S0898-6568(97)00097-1. PMID 9481484.
- Dulin NO, Sorokin A, Reed E, et al. (1999). "RGS3 inhibits G protein-mediated signaling via translocation to the membrane and binding to Galpha11". Mol. Cell. Biol. 19 (1): 714–23. PMC 83928. PMID 9858594.
- Hayes JS, Lawler OA, Walsh MT, Kinsella BT (1999). "The prostacyclin receptor is isoprenylated. Isoprenylation is required for efficient receptor-effector coupling". J. Biol. Chem. 274 (34): 23707–18. doi:10.1074/jbc.274.34.23707. PMID 10446129.
- Brydon L, Roka F, Petit L, et al. (2000). "Dual signaling of human Mel1a melatonin receptors via G(i2), G(i3), and G(q/11) proteins". Mol. Endocrinol. 13 (12): 2025–38. doi:10.1210/me.13.12.2025. PMID 10598579.
- Corbetta S, Mantovani G, Lania A, et al. (2000). "Calcium-sensing receptor expression and signalling in human parathyroid adenomas and primary hyperplasia". Clin. Endocrinol. 52 (3): 339–48. doi:10.1046/j.1365-2265.2000.00933.x. PMID 10718832.
- Shraga-Levine Z, Sokolovsky M (2000). "Functional coupling of G proteins to endothelin receptors is ligand and receptor subtype specific". Cell. Mol. Neurobiol. 20 (3): 305–17. doi:10.1023/A:1007010125316. PMID 10789830.
- AbdAlla S, Lother H, Abdel-tawab AM, Quitterer U (2001). "The angiotensin II AT2 receptor is an AT1 receptor antagonist". J. Biol. Chem. 276 (43): 39721–6. doi:10.1074/jbc.M105253200. PMID 11507095.
This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it. |