Syndrome of inappropriate antidiuretic hormone screening: Difference between revisions
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Diagnosis of SIADH:<ref name="Verbalis-2013">{{Cite journal | last1 = Verbalis | first1 = JG. | last2 = Goldsmith | first2 = SR. | last3 = Greenberg | first3 = A. | last4 = Korzelius | first4 = C. | last5 = Schrier | first5 = RW. | last6 = Sterns | first6 = RH. | last7 = Thompson | first7 = CJ. | title = Diagnosis, evaluation, and treatment of hyponatremia: expert panel recommendations. | journal = Am J Med | volume = 126 | issue = 10 Suppl 1 | pages = S1-42 | month = Oct | year = 2013 | doi = 10.1016/j.amjmed.2013.07.006 | PMID = 24074529 }}</ref> | |||
:* Decreased effective osmolality of the extracellular fluid (Posm <275 mOsmol/kg H2O). | |||
:* Inappropriate urinary concentration (Uosm >100 mOsmol/kg H2O with normal renal function) at some level of plasma hypo-osmolality. | |||
:* Clinical euvolemic hyponatremia (hyponatremia plus normal extra cellular fluid volume) | |||
:* Spot sodium levels ≥ 20-30 mmol/L. | |||
:* Absence of other potential causes of euvolemic hyponatremia: severe hypothyroidism, hypocortisolism. | |||
:* Normal renal function and absence of diuretic use, particularly thiazide diuretics. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} |
Revision as of 17:42, 30 January 2014
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Diagnosis of SIADH:[1]
- Decreased effective osmolality of the extracellular fluid (Posm <275 mOsmol/kg H2O).
- Inappropriate urinary concentration (Uosm >100 mOsmol/kg H2O with normal renal function) at some level of plasma hypo-osmolality.
- Clinical euvolemic hyponatremia (hyponatremia plus normal extra cellular fluid volume)
- Spot sodium levels ≥ 20-30 mmol/L.
- Absence of other potential causes of euvolemic hyponatremia: severe hypothyroidism, hypocortisolism.
- Normal renal function and absence of diuretic use, particularly thiazide diuretics.
References
- ↑ Verbalis, JG.; Goldsmith, SR.; Greenberg, A.; Korzelius, C.; Schrier, RW.; Sterns, RH.; Thompson, CJ. (2013). "Diagnosis, evaluation, and treatment of hyponatremia: expert panel recommendations". Am J Med. 126 (10 Suppl 1): S1–42. doi:10.1016/j.amjmed.2013.07.006. PMID 24074529. Unknown parameter
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