Syndrome of inappropriate antidiuretic hormone overview: Difference between revisions
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The '''syndrome of inappropriate antidiuretic hormone''' (SIADH) is a condition commonly found in the hospital population, especially in patients being hospitalized for [[central nervous system]] (CNS) injury. This is a syndrome characterized by excessive release of [[Vasopressin|antidiuretic hormone]] (ADH or vasopressin) from the [[posterior pituitary]] gland or another source. The result is [[hyponatremia]], and sometimes fluid overload. | The '''syndrome of inappropriate antidiuretic hormone''' (SIADH) is a condition commonly found in the hospital population, especially in patients being hospitalized for [[central nervous system]] (CNS) injury. This is a syndrome characterized by excessive release of [[Vasopressin|antidiuretic hormone]] (ADH or vasopressin) from the [[posterior pituitary]] gland or another source. The result is [[hyponatremia]], and sometimes fluid overload. | ||
Syndrome of inappropriate antidiuretic hormone production (SIADH) is a condition in which the body develops an excess of water and a decrease in [[sodium]] concentration. It may be caused by central nervous system diseases, [[cancer]]s, [[pulmonary disease]]s and some drugs. Signs and aymptoms vary widely. Some patients with SIADH may become severely ill, or may have no symptoms at all. Usual symptoms include [[nausea]], [[vomiting]], [[loss of appetite]], [[fatigue]], [[weakness]],even [[consciousness disorder]]s. Blood tests of [[hyponatremia]] ([[sodium]] <135 mEq/L) and low serum [[osmolality]] (<280 mOsm/kg) may prompt the diagnosis of SIADH. Treatment depends on the causes. Sharp restriction of water intake and addition of a high concentration of sodium may get immediate improvement. Prognosis of SIADH varies widely, depending on the causes. | |||
==References== | ==References== | ||
Revision as of 11:27, 20 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The syndrome of inappropriate antidiuretic hormone (SIADH) is a condition commonly found in the hospital population, especially in patients being hospitalized for central nervous system (CNS) injury. This is a syndrome characterized by excessive release of antidiuretic hormone (ADH or vasopressin) from the posterior pituitary gland or another source. The result is hyponatremia, and sometimes fluid overload.
Syndrome of inappropriate antidiuretic hormone production (SIADH) is a condition in which the body develops an excess of water and a decrease in sodium concentration. It may be caused by central nervous system diseases, cancers, pulmonary diseases and some drugs. Signs and aymptoms vary widely. Some patients with SIADH may become severely ill, or may have no symptoms at all. Usual symptoms include nausea, vomiting, loss of appetite, fatigue, weakness,even consciousness disorders. Blood tests of hyponatremia (sodium <135 mEq/L) and low serum osmolality (<280 mOsm/kg) may prompt the diagnosis of SIADH. Treatment depends on the causes. Sharp restriction of water intake and addition of a high concentration of sodium may get immediate improvement. Prognosis of SIADH varies widely, depending on the causes.