Follicular lymphoma laboratory findings: Difference between revisions

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{{Follicular lymphoma}}
{{Follicular lymphoma}}
{{CMG}}; {{AE}} {{AS}}
 
==Overview==
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Laboratory tests in the diagnosis of follicular lymphoma include histological confirmation, immunophenotyping, immunohistochemistry, molecular genetic analysis and cytogenetics.
==Laboratory Findings==
Laboratory findings consistent with the diagnosis of follicular lymphoma includes<ref>{{cite web | title = Non-Hodgkin's Lymphomas (NCCN.org) | url = http://www.nccn.org/professionals/physician_gls/PDF/nhl.pdf }}</ref>
* Histological confirmation by centroblasts and centrocytes
* Immunophenotyping using flow cytometry to detect immunophenotypes like CD20+, CD10+, BCL2+, CD23+/-, CD43-, CD5-, CCND1-, CD10-, BCL2- and BCL6+
* Immunohistochemistry for Ki-67,Aggressive clinical behavior is in association with low-grade follicular lymphoma with a high proliferation index. ( determined by Ki-67 immunostaining)
* Molecular genetic analysis for BCL2 rearrangement
* Cytogenetics or FISH for t(14;18)


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


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[[Category:Hematology]]
[[Category:Hematology]]
[[Category:Types of cancer]]
[[Category:Types of cancer]]

Revision as of 14:23, 26 August 2015