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Nearly all chondrosarcoma patients appear to be in good health. Since it is not like other cancers, it doesn't affect the whole system. Many patients are not aware that there is a tumor growing inside them until there is a noticeable lump or pain. Sometimes a patient has no symptoms and no awareness of any lump and perhaps, by having a test for something else gets diagnosed accidentally. Sometimes an unexpected fracture will be the first indication of a bone tumor.[http://www.caringmedical.com/conditions/Chondrosarcoma.htm] | Nearly all chondrosarcoma patients appear to be in good health. Since it is not like other cancers, it doesn't affect the whole system. Many patients are not aware that there is a tumor growing inside them until there is a noticeable lump or pain. Sometimes a patient has no symptoms and no awareness of any lump and perhaps, by having a test for something else gets diagnosed accidentally. Sometimes an unexpected fracture will be the first indication of a bone tumor.[http://www.caringmedical.com/conditions/Chondrosarcoma.htm] | ||
==Classification== | |||
Chondrosarcoma may be classified into six subtypes based on topographical location of tumor, histological characteristics, makeup of surrounding matrix material. | |||
==Pathophysiology== | |||
On gross pathology, Greyish-white lobulated mass, [[necrosis]], [[calcification]], mucoid degeneration are characteristic findings of chondrosarcoma. On microscopic histopathological analysis abnormal [[cartilage]], increased cellularity, nuclear atypia are characteristic findings of chondrosarcoma. Chondrosarcoma may be divided into three grades based on cancer cells morphology under microscope and growth rate of [[tumor]]. | |||
==Differential Diagnosis== | |||
Chondrosarcoma must be differentiated from other diseases such as [[chondroma]], [[enchondroma]], [[synovial chondromatosis]], [[osteosarcoma]]. | |||
==References== | ==References== | ||
Revision as of 18:40, 31 August 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
A chondrosarcoma is a particular cancer of the bone. Chondrosarcoma is a cartilage based tumor and is in a category of cancers called sarcomas. Chondrosarcoma is a rare cancer that can affect people (and animals) of any age. The aggressiveness of chondrosarcoma is graded based on how fast it grows and its likelihood to metastasize or spread to other parts of the body. Grade 1 is a low grade (slow growing) cancer, and grades 2 and 3 are higher grades (fast growing) cancers. Depending on the grading system used by your medical facility, it's also possible to have grade 4 which would be even more aggressive than lower grade tumors. The most common bones for chondrosarcoma to grow are the pelvic and shoulder bones along with the superior regions of the arms and legs. [2] But they can also be found in any bones of the body, even in the base of the skull.
Nearly all chondrosarcoma patients appear to be in good health. Since it is not like other cancers, it doesn't affect the whole system. Many patients are not aware that there is a tumor growing inside them until there is a noticeable lump or pain. Sometimes a patient has no symptoms and no awareness of any lump and perhaps, by having a test for something else gets diagnosed accidentally. Sometimes an unexpected fracture will be the first indication of a bone tumor.[3]
Classification
Chondrosarcoma may be classified into six subtypes based on topographical location of tumor, histological characteristics, makeup of surrounding matrix material.
Pathophysiology
On gross pathology, Greyish-white lobulated mass, necrosis, calcification, mucoid degeneration are characteristic findings of chondrosarcoma. On microscopic histopathological analysis abnormal cartilage, increased cellularity, nuclear atypia are characteristic findings of chondrosarcoma. Chondrosarcoma may be divided into three grades based on cancer cells morphology under microscope and growth rate of tumor.
Differential Diagnosis
Chondrosarcoma must be differentiated from other diseases such as chondroma, enchondroma, synovial chondromatosis, osteosarcoma.