Follicular lymphoma natural history, complications and prognosis: Difference between revisions
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Prognosis is generally poor and the 5 year survival rate of patients with follicular lymphoma is approximately 72-77%. | Prognosis is generally poor and the 5 year survival rate of patients with follicular lymphoma is approximately 72-77%. | ||
==Prognosis== | ==Prognosis== | ||
*Follicular lymphoma is regarded as incurable (although allogenic [[stem cell transplantation]] may be curative, the mortality from the procedure is too high to be a first line option). The [[median]] survival is around 10 years, but the range is wide, from less than one year, to more than 20 years. Some patients may never need treatment. The overall survival rate at 5 years is 72-77%<ref>{{EMedicine|article|203268|Lymphoma, Follicular}}</ref> | *Follicular lymphoma is regarded as incurable (although allogenic [[stem cell transplantation]] may be curative, the mortality from the procedure is too high to be a first line option). The [[median]] survival is around 10 years, but the range is wide, from less than one year, to more than 20 years. Some patients may never need treatment. The overall survival rate at 5 years is 72-77%.<ref>{{EMedicine|article|203268|Lymphoma, Follicular}}</ref> | ||
* | *The following factors are associated with poor prognosis:<ref name="seer">National Cancer Institute. Surveillance, Epidemiology, and End Results Program 2015. http://seer.cancer.gov</ref>. | ||
* | :*Grade 3 histopathologic grading | ||
* | :*Presence of cytogenic abnormalities of ''BCL-6'' gene | ||
==References== | ==References== |
Revision as of 13:55, 2 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Prognosis is generally poor and the 5 year survival rate of patients with follicular lymphoma is approximately 72-77%.
Prognosis
- Follicular lymphoma is regarded as incurable (although allogenic stem cell transplantation may be curative, the mortality from the procedure is too high to be a first line option). The median survival is around 10 years, but the range is wide, from less than one year, to more than 20 years. Some patients may never need treatment. The overall survival rate at 5 years is 72-77%.[1]
- The following factors are associated with poor prognosis:[2].
- Grade 3 histopathologic grading
- Presence of cytogenic abnormalities of BCL-6 gene
References
- ↑ Lymphoma, Follicular at eMedicine
- ↑ National Cancer Institute. Surveillance, Epidemiology, and End Results Program 2015. http://seer.cancer.gov