Transitional cell carcinoma classification: Difference between revisions
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:*Urothelial papilloma | :*Urothelial papilloma | ||
:*Inverted urothelial papilloma | :*Inverted urothelial papilloma | ||
===Grading=== | |||
According to the WHO grading criteria, there are three grades of transitional cell carcinoma based on the degree of cellular differentiation:<ref name="Grignon2009">{{cite journal|last1=Grignon|first1=David J|title=The current classification of urothelial neoplasms|journal=Modern Pathology|volume=22|year=2009|pages=S60–S69|issn=0893-3952|doi=10.1038/modpathol.2008.235}}</ref> | |||
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! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|'''Grade'''}} | |||
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|'''Description'''}} | |||
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Grade 1 | |||
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*Tumors with the least degree of cellular anaplasia compatible with a diagnosis of malignancy | |||
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Grade 2 | |||
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*Histologic features between grades 1 and 3 | |||
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Grade 3 | |||
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*Tumors with the most severe degrees of cellular anaplasia | |||
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==References== | ==References== |
Revision as of 20:53, 11 February 2016
Transitional cell carcinoma Microchapters |
Differentiating Transitional cell carcinoma from other Diseases |
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Directions to Hospitals Treating Transitional cell carcinoma |
Risk calculators and risk factors for Transitional cell carcinoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Classification
In the United States, bladder cancers usually start from the cells lining the bladder (called transitional cells).
These tumors are classified based on the way they grow:
- Papillary tumors have a wart-like appearance and are attached to a stalk.
- Nonpapillary (sessile) tumors are much less common. However, they are more invasive and have a worse outcome.
- Infiltrating urothelial carcinoma
- with squamous differentiation
- with glandular differentiation
- with trophoblastic differentiation
- Nested
- Microcystic
- Micropapillary
- Lymphoepithelioma-like
- Lymphoma-like
- Plasmacytoid
- Sarcomatoid
- Giant cell
- Undifferentiated
- Non-invasive urothelial neoplasias
- Urothelial carcinoma in situ
- Non-invasive papillary urothelial carcinoma, high grade
- Non-invasive papillary urothelial carcinoma, low grade
- Non-invasive papillary urothelial neoplasm of low
- Malignant potential
- Urothelial papilloma
- Inverted urothelial papilloma
Grading
According to the WHO grading criteria, there are three grades of transitional cell carcinoma based on the degree of cellular differentiation:[1]
Grade | Description |
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Grade 1 |
|
Grade 2 |
|
Grade 3 |
|
References
- ↑ Grignon, David J (2009). "The current classification of urothelial neoplasms". Modern Pathology. 22: S60–S69. doi:10.1038/modpathol.2008.235. ISSN 0893-3952.