Transitional cell carcinoma epidemiology and demographics: Difference between revisions
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==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
Transitional cell carcinomas of upper urinary tract are rare cancers accounting for 5-7% of transitional cell cancers.<ref name="KirkaliTuzel2003">{{cite journal|last1=Kirkali|first1=Ziya|last2=Tuzel|first2=Emre|title=Transitional cell carcinoma of the ureter and renal pelvis|journal=Critical Reviews in Oncology/Hematology|volume=47|issue=2|year=2003|pages=155–169|issn=10408428|doi=10.1016/S1040-8428(03)00079-9}}</ref> | Transitional cell carcinomas of upper urinary tract are rare cancers accounting for 5-7% of transitional cell cancers.<ref name="KirkaliTuzel2003">{{cite journal|last1=Kirkali|first1=Ziya|last2=Tuzel|first2=Emre|title=Transitional cell carcinoma of the ureter and renal pelvis|journal=Critical Reviews in Oncology/Hematology|volume=47|issue=2|year=2003|pages=155–169|issn=10408428|doi=10.1016/S1040-8428(03)00079-9}}</ref> | ||
*Transitional cell carcinoma of the renal pelvis, accounts for only 7% of all kidney tumors.<ref name= NIH>Transitional cell cancer. National cancer institute. http://www.cancer.gov/types/kidney/hp/transitional-cell-treatment-pdq#section/_1</ref> | *Transitional cell carcinoma of the renal pelvis, accounts for only 7% of all kidney tumors.<ref name= NIH>Transitional cell cancer. National cancer institute. http://www.cancer.gov/types/kidney/hp/transitional-cell-treatment-pdq#section/_1</ref> | ||
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*Patients with deeply invasive tumors that are still confined to the renal pelvis or ureter have a 10% to 15% likelihood of cure. | *Patients with deeply invasive tumors that are still confined to the renal pelvis or ureter have a 10% to 15% likelihood of cure. | ||
*Patients with tumors with penetration through the urothelial wall or with distant metastases usually cannot be cured with currently available forms of treatment. | *Patients with tumors with penetration through the urothelial wall or with distant metastases usually cannot be cured with currently available forms of treatment. | ||
===Incidence=== | |||
*The incidence of upper urinary tract transitional cell carcinoma was estimated to be 0.6-1.1 cases per 100,000 individuals worldwide.<ref name="KirkaliTuzel2003">{{cite journal|last1=Kirkali|first1=Ziya|last2=Tuzel|first2=Emre|title=Transitional cell carcinoma of the ureter and renal pelvis|journal=Critical Reviews in Oncology/Hematology|volume=47|issue=2|year=2003|pages=155–169|issn=10408428|doi=10.1016/S1040-8428(03)00079-9}}</ref> | |||
===Age=== | ===Age=== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Epidemiology and Demographics
Transitional cell carcinomas of upper urinary tract are rare cancers accounting for 5-7% of transitional cell cancers.[1]
- Transitional cell carcinoma of the renal pelvis, accounts for only 7% of all kidney tumors.[2]
- Transitional cell cancer of the ureter, accounts for only 1 of every 25 upper tract tumors.
- They are curable in more than 90% of patients if they are superficial and confined to the renal pelvis or ureter.
- Patients with deeply invasive tumors that are still confined to the renal pelvis or ureter have a 10% to 15% likelihood of cure.
- Patients with tumors with penetration through the urothelial wall or with distant metastases usually cannot be cured with currently available forms of treatment.
Incidence
- The incidence of upper urinary tract transitional cell carcinoma was estimated to be 0.6-1.1 cases per 100,000 individuals worldwide.[1]
Age
- Transitional cell carcinoma commonly affects individuals older than 60 years of age with the average age of presentation being 65.
- Transitional cell carcinoma of the urinary bladder is rare in young adults, as less than 1% of such tumors present in the first 4 decades of life.[3]
Gender
There is a strong male predilection (M:F = 2:1), at least in part due to many tumors (especially historically) having been due to industrial exposure.
References
- ↑ 1.0 1.1 Kirkali, Ziya; Tuzel, Emre (2003). "Transitional cell carcinoma of the ureter and renal pelvis". Critical Reviews in Oncology/Hematology. 47 (2): 155–169. doi:10.1016/S1040-8428(03)00079-9. ISSN 1040-8428.
- ↑ Transitional cell cancer. National cancer institute. http://www.cancer.gov/types/kidney/hp/transitional-cell-treatment-pdq#section/_1
- ↑ Nomikos, Michael; Pappas, Athanasios; Kopaka, Maria-Emmanouela; Tzoulakis, Stavros; Volonakis, Ioannis; Stavrakakis, Georgios; Avgenakis, Georgios; Anezinis, Ploutarchos (2011). "Urothelial Carcinoma of the Urinary Bladder in Young Adults: Presentation, Clinical behavior and Outcome". Advances in Urology. 2011: 1–4. doi:10.1155/2011/480738. ISSN 1687-6369.