Stomatitis laboratory findings: Difference between revisions
Jump to navigation
Jump to search
Usama Talib (talk | contribs) No edit summary |
Usama Talib (talk | contribs) No edit summary |
||
| Line 4: | Line 4: | ||
==Overview== | ==Overview== | ||
History and physical examination are the mainstay of diagnosing stomatitis. Laboratory findings can play an important role in diagnosing and differentiating the particular type of stomatitis. | [[History and Physical examination|History and physical examination]] are the mainstay of diagnosing stomatitis. Laboratory findings can play an important role in diagnosing and differentiating the particular type of stomatitis. | ||
==Laboratory findings== | ==Laboratory findings== | ||
History and physical examination are the mainstay of diagnosing stomatitis. If required laboratory findings can play an important role in diagnosing and differentiating the particular type of stomatitis. | [[History and Physical examination|History and physical examination]] are the mainstay of diagnosing stomatitis. If required laboratory findings can play an important role in diagnosing and differentiating the particular type of stomatitis. | ||
===Herpetic Stomatitis=== | ===[[Herpetic stomatitis|Herpetic Stomatitis]]=== | ||
*Viral culture | *[[Viral culture]] | ||
*Tzank smear for active lesions | *Tzank smear for active [[lesions]] | ||
**It can not differentiate between the various types of viruses that can cause stomatitis i.e [[ | **It can not differentiate between the various types of viruses that can cause stomatitis i.e [[HSV-1]], [[HSV-2]] or [[VZV]] | ||
*Serology | *[[Serology]] | ||
*Studies using immunofluorescent techniques | *Studies using [[Immunofluorescence|immunofluorescent techniques]] | ||
*[[PCR]] | *[[PCR]] | ||
===Noma or Gangrenous stomatitis=== | ===[[Noma]] or [[Gangrenous stomatitis]]=== | ||
The diagnosis of Noma or gangrenous stomatitis is made by:<ref name="Gangrenous stomatitis">{{cite book |last1=Mandell |firs1t=Gerald |last2=Gouglas |first2=Gordon |last3=Bennett |first3=John |date= |title=Principles and Practice of Infectious Diseases |location= Harvard Medical School |publisher=WILEY MEDICAL |page=383 |isbn=0-471-87643-7}}</ref> | The [[diagnosis]] of Noma or gangrenous stomatitis is made by:<ref name="Gangrenous stomatitis">{{cite book |last1=Mandell |firs1t=Gerald |last2=Gouglas |first2=Gordon |last3=Bennett |first3=John |date= |title=Principles and Practice of Infectious Diseases |location= Harvard Medical School |publisher=WILEY MEDICAL |page=383 |isbn=0-471-87643-7}}</ref> | ||
*Culture of organisms | *Culture of organisms | ||
*Biopsy showing deep tissue involvement | *Biopsy showing deep tissue involvement | ||
===Pyostomatitis vegetans=== | ===Pyostomatitis vegetans=== | ||
*Immunofluorescence testing<ref name="pmid28153136">Magliocca KR, Fitzpatrick SG (2017) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=28153136 Autoimmune Disease Manifestations in the Oral Cavity.] ''Surg Pathol Clin'' 10 (1):57-88. [http://dx.doi.org/10.1016/j.path.2016.11.001 DOI:10.1016/j.path.2016.11.001] PMID: [https://pubmed.gov/28153136 28153136]</ref> | *[[Immunofluorescence|Immunofluorescence testing]]<ref name="pmid28153136">Magliocca KR, Fitzpatrick SG (2017) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=28153136 Autoimmune Disease Manifestations in the Oral Cavity.] ''Surg Pathol Clin'' 10 (1):57-88. [http://dx.doi.org/10.1016/j.path.2016.11.001 DOI:10.1016/j.path.2016.11.001] PMID: [https://pubmed.gov/28153136 28153136]</ref> | ||
*Biopsy (showing hyperplasia of the stratified | *[[Biopsy]] (showing [[hyperplasia]] of the [[stratified squamous epithelium]])<ref name="pmid23138121">{{cite journal| author=Wang H, Qiao S, Zhang X, Liu C| title=A case of pyodermatitis-pyostomatitis vegetans. | journal=Am J Med Sci | year= 2013 | volume= 345 | issue= 2 | pages= 168-71 | pmid=23138121 | doi=10.1097/MAJ.0b013e31826c5a82 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23138121 }} </ref> | ||
*[[Eosinophils]], [[neutrophils]], [[plasma cells]] and [[lymphocytes]] in the connective tissue. Spongiotic changes may also be noticed.<ref name="pmid20689401">{{cite journal| author=Abellaneda C, Mascaró JM, Vázquez MG, Pablo IM, Iranzo P| title=All that glitters is not pemphigus: Pyodermatitis-pyostomatitis vegetans misdiagnosed as IgA pemphigus for 8 years. | journal=Am J Dermatopathol | year= 2011 | volume= 33 | issue= 1 | pages= e1-6 | pmid=20689401 | doi=10.1097/DAD.0b013e3181d81ecb | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20689401 }} </ref> | *[[Eosinophils]], [[neutrophils]], [[plasma cells]] and [[lymphocytes]] in the connective tissue. Spongiotic changes may also be noticed.<ref name="pmid20689401">{{cite journal| author=Abellaneda C, Mascaró JM, Vázquez MG, Pablo IM, Iranzo P| title=All that glitters is not pemphigus: Pyodermatitis-pyostomatitis vegetans misdiagnosed as IgA pemphigus for 8 years. | journal=Am J Dermatopathol | year= 2011 | volume= 33 | issue= 1 | pages= e1-6 | pmid=20689401 | doi=10.1097/DAD.0b013e3181d81ecb | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20689401 }} </ref> | ||
Revision as of 17:51, 20 March 2017
|
Stomatitis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Stomatitis laboratory findings On the Web |
|
American Roentgen Ray Society Images of Stomatitis laboratory findings |
|
Risk calculators and risk factors for Stomatitis laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mehrsefat, M.D. [2], Usama Talib, BSc, MD [3]
Overview
History and physical examination are the mainstay of diagnosing stomatitis. Laboratory findings can play an important role in diagnosing and differentiating the particular type of stomatitis.
Laboratory findings
History and physical examination are the mainstay of diagnosing stomatitis. If required laboratory findings can play an important role in diagnosing and differentiating the particular type of stomatitis.
Herpetic Stomatitis
- Viral culture
- Tzank smear for active lesions
- Serology
- Studies using immunofluorescent techniques
- PCR
Noma or Gangrenous stomatitis
The diagnosis of Noma or gangrenous stomatitis is made by:[1]
- Culture of organisms
- Biopsy showing deep tissue involvement
Pyostomatitis vegetans
- Immunofluorescence testing[2]
- Biopsy (showing hyperplasia of the stratified squamous epithelium)[3]
- Eosinophils, neutrophils, plasma cells and lymphocytes in the connective tissue. Spongiotic changes may also be noticed.[4]
References
- ↑ Mandell; Gouglas, Gordon; Bennett, John. Principles and Practice of Infectious Diseases. Harvard Medical School: WILEY MEDICAL. p. 383. ISBN 0-471-87643-7. Unknown parameter
|firs1t=ignored (help) - ↑ Magliocca KR, Fitzpatrick SG (2017) Autoimmune Disease Manifestations in the Oral Cavity. Surg Pathol Clin 10 (1):57-88. DOI:10.1016/j.path.2016.11.001 PMID: 28153136
- ↑ Wang H, Qiao S, Zhang X, Liu C (2013). "A case of pyodermatitis-pyostomatitis vegetans". Am J Med Sci. 345 (2): 168–71. doi:10.1097/MAJ.0b013e31826c5a82. PMID 23138121.
- ↑ Abellaneda C, Mascaró JM, Vázquez MG, Pablo IM, Iranzo P (2011). "All that glitters is not pemphigus: Pyodermatitis-pyostomatitis vegetans misdiagnosed as IgA pemphigus for 8 years". Am J Dermatopathol. 33 (1): e1–6. doi:10.1097/DAD.0b013e3181d81ecb. PMID 20689401.